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ChemicalBook >> CAS DataBase List >> Birinapant

Birinapant

Birinapant price.
  • $57 - $4023.9
  • Product name: Birinapant
  • CAS: 1260251-31-7
  • MF: C42H56F2N8O6
  • MW: 806.94
  • EINECS:
  • MDL Number:MFCD25976869
  • Synonyms:Birinapant;Birinapant (TL32711);TL 32711;Birinapant(TL32711)/TL-32711/TL32711/TL-32711;(2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide;Propanamide, N,N'-[(6,6'-difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-, (2S,2'S)-;(2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide Birinapant TL 32711;Birinapant (2S,2'S)-N,N'-[(6,6'-Difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-propanamide
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5734
  • Product descriptionBirinapant
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4219
  • Product descriptionBirinapant(TL32711)
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60279
  • Product descriptionBirinapant ≥98%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146223
  • Product descriptionBirinapant (TL32711) >98%
  • Packaging100mg
  • Price$986
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146223
  • Product descriptionBirinapant (TL32711) >98%
  • Packaging250mg
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146223
  • Product descriptionBirinapant (TL32711) >98%
  • Packaging1g
  • Price$4023.9
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19699
  • Product descriptionBirinapant ≥95%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19699
  • Product descriptionBirinapant ≥95%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19699
  • Product descriptionBirinapant ≥95%
  • Packaging10mg
  • Price$330
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19699
  • Product descriptionBirinapant ≥95%
  • Packaging25mg
  • Price$616
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004061
  • Product descriptionBirinapant 98+%
  • Packaging5mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004061
  • Product descriptionBirinapant 98+%
  • Packaging10mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004061
  • Product descriptionBirinapant 98+%
  • Packaging50mg
  • Price$595
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004061
  • Product descriptionBirinapant 98+%
  • Packaging100mg
  • Price$945
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC5023
  • Product descriptionBirinapant(TL32711) >98%
  • Packaging1g
  • Price$2700
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB399730
  • Product descriptionBirinapant
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5734 Birinapant 10mg $170 2021-12-16 Buy
ApexBio Technology A4219 Birinapant(TL32711) 5mg $90 2021-12-16 Buy
Arctom CFN60279 Birinapant ≥98% 10mg $288 2021-12-16 Buy
Biorbyt Ltd orb146223 Birinapant (TL32711) >98% 100mg $986 2021-12-16 Buy
Biorbyt Ltd orb146223 Birinapant (TL32711) >98% 250mg $1949.9 2021-12-16 Buy
Biorbyt Ltd orb146223 Birinapant (TL32711) >98% 1g $4023.9 2021-12-16 Buy
Cayman Chemical 19699 Birinapant ≥95% 1mg $57 2024-03-01 Buy
Cayman Chemical 19699 Birinapant ≥95% 5mg $193 2024-03-01 Buy
Cayman Chemical 19699 Birinapant ≥95% 10mg $330 2024-03-01 Buy
Cayman Chemical 19699 Birinapant ≥95% 25mg $616 2024-03-01 Buy
Crysdot CD31004061 Birinapant 98+% 5mg $126 2021-12-16 Buy
Crysdot CD31004061 Birinapant 98+% 10mg $196 2021-12-16 Buy
Crysdot CD31004061 Birinapant 98+% 50mg $595 2021-12-16 Buy
Crysdot CD31004061 Birinapant 98+% 100mg $945 2021-12-16 Buy
DC Chemicals DC5023 Birinapant(TL32711) >98% 1g $2700 2021-12-16 Buy
TRC B399730 Birinapant 5mg $140 2021-12-16 Buy

Properties

Melting point :>245oC (dec.)
Boiling point :1090.5±65.0 °C(Predicted)
Density :1.320±0.06(20.0000℃)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :13.99±0.46(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Birinapant is a bivalent mimetic of the Diablo homolog known as second mitochondria-derived activator of caspase (Smac). It is an antagonist of cellular inhibitor of apoptosis 1 (cIAP1, or BIRC2), cIAP2 (BIRC3), and XIAP (BIRC4), binding each at nanomolar concentrations. Birinapant causes rapid cIAP1 degradation, caspase activation, PARP cleavage, and NF-κB activation in breast cancer cells. It shows in vivo antitumor activity, inducing apoptosis in several types of cancer xenografts in mice.

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