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ChemicalBook >> CAS DataBase List >> PLX4032

PLX4032

PLX4032 price.
  • $29 - $3960
  • Product name: PLX4032
  • CAS: 918504-65-1
  • MF: C23H18ClF2N3O3S
  • MW: 489.92
  • EINECS:
  • MDL Number:MFCD18074504
  • Synonyms:N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide;PLX4032 (VeMurafenib);PLX4032, RG7204, ZELBORAF, RO5185426;R7204;N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaM;PLX4032, R7204, RG7204, RO5185426;VeMurafenib (PLX4032, RG7204);N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Vemurafenib PLX 4032
32 prices
Selected condition:
Brand
  • Abosyn
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 5mg
  • 10mg
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  • 25MG
  • 50mg
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  • 200mg
  • 250mg
  • 0.25g
  • 500mg
  • 1g
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  • 5g
  • 10g
  • ManufacturerAbosyn
  • Product number61-5714
  • Product descriptionN-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 97+%
  • Packaging0.25g
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1161-M005
  • Product descriptionPLX4032 ≥95%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0473
  • Product descriptionVemurafenib
  • Packaging1g
  • Price$929
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045862
  • Product descriptionVEMURAFENIB 95.00%
  • Packaging5MG
  • Price$911.72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045862
  • Product descriptionVEMURAFENIB 95.00%
  • Packaging25MG
  • Price$1450
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045862
  • Product descriptionVEMURAFENIB 95.00%
  • Packaging100MG
  • Price$1950
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3004
  • Product descriptionVemurafenib(PLX4032,RG7204)
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60058
  • Product descriptionVemurafenib(PLX4032) ≥98%
  • Packaging20mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3087
  • Product descriptionVemurafenib
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3087
  • Product descriptionVemurafenib
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3087
  • Product descriptionVemurafenib
  • Packaging100mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3087
  • Product descriptionVemurafenib
  • Packaging1g
  • Price$229
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1624
  • Product descriptionPLX4032-RG7204|Vemurafenib|RO5185426 98%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10618
  • Product descriptionPLX4032 ≥98%
  • Packaging5mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10618
  • Product descriptionPLX4032 ≥98%
  • Packaging10mg
  • Price$70
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10618
  • Product descriptionPLX4032 ≥98%
  • Packaging25mg
  • Price$161
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-5714 N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 97+% 0.25g $520 2021-12-16 Buy
Adipogen Life Sciences SYN-1161-M005 PLX4032 ≥95% 5mg $70 2021-12-16 Buy
AK Scientific Y0473 Vemurafenib 1g $929 2021-12-16 Buy
American Custom Chemicals Corporation API0045862 VEMURAFENIB 95.00% 5MG $911.72 2021-12-16 Buy
American Custom Chemicals Corporation API0045862 VEMURAFENIB 95.00% 25MG $1450 2021-12-16 Buy
American Custom Chemicals Corporation API0045862 VEMURAFENIB 95.00% 100MG $1950 2021-12-16 Buy
ApexBio Technology A3004 Vemurafenib(PLX4032,RG7204) 50mg $120 2021-12-16 Buy
Arctom CFN60058 Vemurafenib(PLX4032) ≥98% 20mg $148 2021-12-16 Buy
AvaChem 3087 Vemurafenib 10mg $29 2021-12-16 Buy
AvaChem 3087 Vemurafenib 25mg $49 2021-12-16 Buy
AvaChem 3087 Vemurafenib 100mg $89 2021-12-16 Buy
AvaChem 3087 Vemurafenib 1g $229 2021-12-16 Buy
Axon Medchem Axon1624 PLX4032-RG7204|Vemurafenib|RO5185426 98% 5mg $66 2021-12-16 Buy
Cayman Chemical 10618 PLX4032 ≥98% 5mg $44 2024-03-01 Buy
Cayman Chemical 10618 PLX4032 ≥98% 10mg $70 2024-03-01 Buy
Cayman Chemical 10618 PLX4032 ≥98% 25mg $161 2024-03-01 Buy

Properties

Density :1.46
storage temp. :-20°C
solubility :Soluble in DMSO (up to 100 mg/ml)
form :White powder.
pka :6.26±0.10(Predicted)
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :918504-65-1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the proliferation of B-RafV600E transformed cancer cells. PLX4032 is effective against the growth of tumors bearing the B-Raf V600E mutation.

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