Bosutinib
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- $44 - $1167
- Product name: Bosutinib
- CAS: 380843-75-4
- MF: C26H29Cl2N5O3
- MW: 530.45
- EINECS:700-455-1
- MDL Number:MFCD07367846
- Synonyms:4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;Bosutinib ( SKI-606 );Bosutinib for research;3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-Methoxyphenyl)aMino]-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-;Bosutinib(TINIBS );WAY-173606;Bosulif(bosutinib);4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Bosutinib (SKI-606)
35 prices
Selected condition：
Brand
- AccelPharmtech
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemcia Scientific
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 20mg
- 25mg
- 10
- 5mg
- 10mg
- 50mg
- 2x25mg
- 100mg
- 200mg
- 250mg
- 500mg
- 5g
- 50
- 1g
- 10mM(in 1mL DMSO)
- 10G
- ManufacturerAccelPharmtech
- Product numberAT821010G
- Product descriptionBosutinib 99.00%
- Packaging10G
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberA820
- Product descriptionBosutinib
- Packaging250mg
- Price$326
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2149
- Product descriptionBosutinib(SKI-606)
- Packaging10mM(in 1mL DMSO)
- Price$64
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60155
- Product descriptionBosutinib(SKI-606) ≥98%
- Packaging20mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2435
- Product descriptionBosutinib
- Packaging100mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2435
- Product descriptionBosutinib
- Packaging1g
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1407
- Product descriptionSKI606-Bosutinib 99%
- Packaging2x25mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1407
- Product descriptionSKI606-Bosutinib 99%
- Packaging25mg
- Price$247.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1407
- Product descriptionSKI606-Bosutinib 99%
- Packaging5mg
- Price$82.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146277
- Product descriptionBosutinib (SKI-606) >98%
- Packaging250mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146277
- Product descriptionBosutinib (SKI-606) >98%
- Packaging1g
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19002
- Product descriptionBosutinib
- Packaging25mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19002
- Product descriptionBosutinib
- Packaging50mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19002
- Product descriptionBosutinib
- Packaging100mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19002
- Product descriptionBosutinib
- Packaging250mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19002
- Product descriptionBosutinib
- Packaging500mg
- Price$350
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | AT821010G | Bosutinib 99.00% | 10G | $1000 | 2021-12-16 | Buy |
| AK Scientific | A820 | Bosutinib | 250mg | $326 | 2021-12-16 | Buy |
| ApexBio Technology | A2149 | Bosutinib(SKI-606) | 10mM(in 1mL DMSO) | $64 | 2021-12-16 | Buy |
| Arctom | CFN60155 | Bosutinib(SKI-606) ≥98% | 20mg | $168 | 2021-12-16 | Buy |
| AvaChem | 2435 | Bosutinib | 100mg | $65 | 2021-12-16 | Buy |
| AvaChem | 2435 | Bosutinib | 1g | $375 | 2021-12-16 | Buy |
| Axon Medchem | Axon1407 | SKI606-Bosutinib 99% | 2x25mg | $330 | 2021-12-16 | Buy |
| Axon Medchem | Axon1407 | SKI606-Bosutinib 99% | 25mg | $247.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon1407 | SKI606-Bosutinib 99% | 5mg | $82.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146277 | Bosutinib (SKI-606) >98% | 250mg | $510 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146277 | Bosutinib (SKI-606) >98% | 1g | $765 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19002 | Bosutinib | 25mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19002 | Bosutinib | 50mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19002 | Bosutinib | 100mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19002 | Bosutinib | 250mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB19002 | Bosutinib | 500mg | $350 | 2021-12-16 | Buy |
Properties
Melting point :116-120 ºC
Boiling point :649.7±55.0 °C(Predicted)
Density :1.36
vapor pressure :0-0Pa at 20℃
storage temp. :room temp
solubility :DMSO: ≥15mg/mL
pka :7.63±0.10(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PICKMQXYAMDEPF-UHFFFAOYSA-N
LogP :3.3-4.3 at pH9.5
Surface tension :72.4mN/m at 3.6mg/L and 20℃
CAS DataBase Reference :380843-75-4(CAS DataBase Reference)
Boiling point :649.7±55.0 °C(Predicted)
Density :1.36
vapor pressure :0-0Pa at 20℃
storage temp. :room temp
solubility :DMSO: ≥15mg/mL
pka :7.63±0.10(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PICKMQXYAMDEPF-UHFFFAOYSA-N
LogP :3.3-4.3 at pH9.5
Surface tension :72.4mN/m at 3.6mg/L and 20℃
CAS DataBase Reference :380843-75-4(CAS DataBase Reference)
Safety Information
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Description
The non-receptor tyrosine kinases c-Src and Abl have important roles in cell signaling and cancer. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib also inhibits, at nanomolar concentrations, other members of the Src family (e.g., Yes, Fgr, Lck, Fyn), as well as members of the TEC family, and certain other kinases. These actions extend the usefulness of this compound to cancers beyond those involving Src and Abl.More related product prices
(Trifluoromethoxy)benzene Dichlorodiphenylsilane Acetonitrile 4-Methoxyphenylacetone 149-74-6 Methanol Methyl acrylate Paraquat dichloride Kresoxim-methyl Methylparaben Nimesulide 2-Methoxyethanol 387867-13-2 3-ACETAMIDOPHENOL N,N'-Diisopropylcarbodiimide 3,4-Dimethoxynitrobenzene BosutinibRelated product price
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