Bosutinib
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- $10 - $2200
- Product name: Bosutinib
- CAS: 380843-75-4
- MF: C26H29Cl2N5O3
- MW: 530.45
- EINECS:700-455-1
- MDL Number:MFCD07367846
- Synonyms:4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;Bosutinib ( SKI-606 );Bosutinib for research;3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-Methoxyphenyl)aMino]-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-;Bosutinib(TINIBS );WAY-173606;Bosulif(bosutinib);4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Bosutinib (SKI-606)
84 prices
Selected condition：
Brand
- A2B
- AccelPharmtech
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemcia Scientific
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- Usbiological
Package
- 20mg
- 25mg
- 10mM(in 1mL DMSO)
- 50mg
- 10
- 2x25mg
- 50
- 200mg
- 500mg
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- 25g
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging10mg
- Price$20
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging1mg
- Price$10
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging100mg
- Price$31
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging250mg
- Price$40
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging1g
- Price$105
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging5g
- Price$344
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging10g
- Price$523
- Updated2026-05-25
- Buy
- ManufacturerA2B
- Product numberAF56672
- Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
- Packaging25g
- Price$1038
- Updated2026-05-25
- Buy
- ManufacturerAccelPharmtech
- Product numberAT821010G
- Product descriptionBosutinib 99.00%
- Packaging
- Price$1000
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT821010G
- Product descriptionBosutinib 99.00%
- Packaging10G
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8210
- Product descriptionBosutinib 99.00%
- Packaging5G
- Price$540
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT8210
- Product descriptionBosutinib 99.00%
- Packaging1G
- Price$190
- Updated2026-05-21
- Buy
- ManufacturerAK Scientific
- Product numberA820
- Product descriptionBosutinib
- Packaging250mg
- Price$326
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2149
- Product descriptionBosutinib (SKI-606)
- Packaging100mg
- Price$129
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2149
- Product descriptionBosutinib (SKI-606)
- Packaging5mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2149
- Product descriptionBosutinib (SKI-606)
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 10mg | $20 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 1mg | $10 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 100mg | $31 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 250mg | $40 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 1g | $105 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 5g | $344 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 10g | $523 | 2026-05-25 | Buy |
| A2B | AF56672 | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% | 25g | $1038 | 2026-05-25 | Buy |
| AccelPharmtech | AT821010G | Bosutinib 99.00% | $1000 | 2026-05-21 | Buy | |
| AccelPharmtech | AT821010G | Bosutinib 99.00% | 10G | $1000 | 2021-12-16 | Buy |
| AccelPharmtech | AT8210 | Bosutinib 99.00% | 5G | $540 | 2026-05-21 | Buy |
| AccelPharmtech | AT8210 | Bosutinib 99.00% | 1G | $190 | 2026-05-21 | Buy |
| AK Scientific | A820 | Bosutinib | 250mg | $326 | 2021-12-16 | Buy |
| ApexBio Technology | A2149 | Bosutinib (SKI-606) | 100mg | $129 | 2026-05-06 | Buy |
| ApexBio Technology | A2149 | Bosutinib (SKI-606) | 5mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | A2149 | Bosutinib (SKI-606) | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
Properties
Melting point :116-120 ºC
Boiling point :649.7±55.0 °C(Predicted)
Density :1.36
vapor pressure :0-0Pa at 20℃
storage temp. :room temp
solubility :DMSO: ≥15mg/mL
pka :7.63±0.10(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PICKMQXYAMDEPF-UHFFFAOYSA-N
SMILES :N1C2C(=CC(OC)=C(OCCCN3CCN(C)CC3)C=2)C(NC2=CC(OC)=C(Cl)C=C2Cl)=C(C#N)C=1
LogP :3.3-4.3 at pH9.5
Surface tension :72.4mN/m at 3.6mg/L and 20℃
CAS DataBase Reference :380843-75-4(CAS DataBase Reference)
Boiling point :649.7±55.0 °C(Predicted)
Density :1.36
vapor pressure :0-0Pa at 20℃
storage temp. :room temp
solubility :DMSO: ≥15mg/mL
pka :7.63±0.10(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PICKMQXYAMDEPF-UHFFFAOYSA-N
SMILES :N1C2C(=CC(OC)=C(OCCCN3CCN(C)CC3)C=2)C(NC2=CC(OC)=C(Cl)C=C2Cl)=C(C#N)C=1
LogP :3.3-4.3 at pH9.5
Surface tension :72.4mN/m at 3.6mg/L and 20℃
CAS DataBase Reference :380843-75-4(CAS DataBase Reference)
Safety Information
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Description
The non-receptor tyrosine kinases c-Src and Abl have important roles in cell signaling and cancer. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib also inhibits, at nanomolar concentrations, other members of the Src family (e.g., Yes, Fgr, Lck, Fyn), as well as members of the TEC family, and certain other kinases. These actions extend the usefulness of this compound to cancers beyond those involving Src and Abl.More related product prices
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