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ChemicalBook >> CAS DataBase List >> Bosutinib

Bosutinib

Bosutinib price.
  • $10 - $2200
  • Product name: Bosutinib
  • CAS: 380843-75-4
  • MF: C26H29Cl2N5O3
  • MW: 530.45
  • EINECS:700-455-1
  • MDL Number:MFCD07367846
  • Synonyms:Bosutinib ( SKI-606 );Bosutinib for research;3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-Methoxyphenyl)aMino]-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-;Bosutinib(TINIBS );WAY-173606;Bosulif(bosutinib);4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Bosutinib (SKI-606);BOSUTINIB (SKI-606);SKI-606
Price125 Properties Safety Information Description
125 prices
Selected condition：
Brand
  • A2B
  • aablocks
  • AccelPharmtech
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  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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  • Tocris
  • Usbiological
Package
  • 5mg
  • 10mM(in 1mL DMSO)
  • 25mg
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  • 1g
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  • 25g
  • 10mM(in1mLDMSO)
  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging1mg
  • Price$10
  • Updated2026-05-25
  • Buy
  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging10mg
  • Price$20
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging100mg
  • Price$31
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging250mg
  • Price$40
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging1g
  • Price$105
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging25g
  • Price$1038
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging10g
  • Price$523
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAF56672
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging5g
  • Price$344
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging10g
  • Price$552
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging5g
  • Price$363
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging25g
  • Price$1096
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging1g
  • Price$124
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97%
  • Packaging250mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 98%(HPLC)
  • Packaging100mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 99%
  • Packaging10mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BXLW
  • Product description4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 99%
  • Packaging1mg
  • Price$11
  • Updated2026-05-28
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 1mg $10 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 10mg $20 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 100mg $31 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 250mg $40 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 1g $105 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 25g $1038 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 10g $523 2026-05-25 Buy
A2B AF56672 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 5g $344 2026-05-25 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 10g $552 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 5g $363 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 25g $1096 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 1g $124 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 97% 250mg $52 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 98%(HPLC) 100mg $32 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 99% 10mg $23 2026-05-28 Buy
aablocks AA00BXLW 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile 99% 1mg $11 2026-05-28 Buy
Next Last

Properties

Melting point :116-120 ºC
Boiling point :649.7±55.0 °C(Predicted)
Density :1.36
vapor pressure :0-0Pa at 20℃
storage temp. :room temp
solubility :DMSO: ≥15mg/mL
pka :7.63±0.10(Predicted)
form :powder
color :off-white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PICKMQXYAMDEPF-UHFFFAOYSA-N
SMILES :N1C2C(=CC(OC)=C(OCCCN3CCN(C)CC3)C=2)C(NC2=CC(OC)=C(Cl)C=C2Cl)=C(C#N)C=1
LogP :3.3-4.3 at pH9.5
Surface tension :72.4mN/m at 3.6mg/L and 20℃
CAS DataBase Reference :380843-75-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The non-receptor tyrosine kinases c-Src and Abl have important roles in cell signaling and cancer. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib is best known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively). Consistent with this action, bosutinib can be effective in regulating tumor growth and differentiation. Bosutinib also inhibits, at nanomolar concentrations, other members of the Src family (e.g., Yes, Fgr, Lck, Fyn), as well as members of the TEC family, and certain other kinases. These actions extend the usefulness of this compound to cancers beyond those involving Src and Abl.

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Suppliers and manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
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Wuhan JiyunZen Tech Co., Ltd.
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career henan chemical co
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AFINE CHEMICALS LIMITED
Capot Chemical Co.,Ltd.
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ATK CHEMICAL COMPANY LIMITED
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