C-DIM12
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- $50 - $900
- Product name: C-DIM12
- CAS: 178946-89-9
- MF: C23H17ClN2
- MW: 356.85
- EINECS:-0
- MDL Number:MFCD05625919
- Synonyms:C-DIM12;C-DIM12(1,1-bis (3'-indolyl)-1-(p-chlorophenyl) methane);C-DIMI2;3,3'-[(4-chlorophenyl)methylene]bis-1H-Indole;C-DIM12, 178946-89-9;C-DIM12 (C-DIM-12;CS-2311;C-DIM12, >98%
18 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number8964CN
- Product description3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole
- Packaging5mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8964CN
- Product description3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole
- Packaging10mg
- Price$202
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8964CN
- Product description3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole
- Packaging25mg
- Price$329
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCBL0015789
- Product descriptionC-DIM12 95.00%
- Packaging5MG
- Price$496.67
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546165
- Product descriptionC-DIM 12 >98%
- Packaging5mg
- Price$163.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546165
- Product descriptionC-DIM 12 >98%
- Packaging25mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22951
- Product descriptionC-DIM12 ≥98%
- Packaging5mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22951
- Product descriptionC-DIM12 ≥98%
- Packaging10mg
- Price$94
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22951
- Product descriptionC-DIM12 ≥98%
- Packaging25mg
- Price$209
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22951
- Product descriptionC-DIM12 ≥98%
- Packaging100mg
- Price$583
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31002934
- Product descriptionC-DIM12 98+%
- Packaging50mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002934
- Product descriptionC-DIM12 98+%
- Packaging100mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002934
- Product descriptionC-DIM12 98+%
- Packaging250mg
- Price$672
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9277
- Product descriptionC-DIM12 >98%
- Packaging100mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9277
- Product descriptionC-DIM12 >98%
- Packaging1g
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5821
- Product descriptionC-DIM12 ≥98%(HPLC)
- Packaging10
- Price$138
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8964CN | 3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole | 5mg | $154 | 2021-12-16 | Buy |
| AK Scientific | 8964CN | 3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole | 10mg | $202 | 2021-12-16 | Buy |
| AK Scientific | 8964CN | 3-[(4-Chlorophenyl)-(1H-indol-3-yl)methyl]-1H-indole | 25mg | $329 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CBL0015789 | C-DIM12 95.00% | 5MG | $496.67 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546165 | C-DIM 12 >98% | 5mg | $163.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546165 | C-DIM 12 >98% | 25mg | $357 | 2021-12-16 | Buy |
| Cayman Chemical | 22951 | C-DIM12 ≥98% | 5mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 22951 | C-DIM12 ≥98% | 10mg | $94 | 2024-03-01 | Buy |
| Cayman Chemical | 22951 | C-DIM12 ≥98% | 25mg | $209 | 2024-03-01 | Buy |
| Cayman Chemical | 22951 | C-DIM12 ≥98% | 100mg | $583 | 2024-03-01 | Buy |
| Crysdot | CD31002934 | C-DIM12 98+% | 50mg | $251 | 2021-12-16 | Buy |
| Crysdot | CD31002934 | C-DIM12 98+% | 100mg | $430 | 2021-12-16 | Buy |
| Crysdot | CD31002934 | C-DIM12 98+% | 250mg | $672 | 2021-12-16 | Buy |
| DC Chemicals | DC9277 | C-DIM12 >98% | 100mg | $250 | 2021-12-16 | Buy |
| DC Chemicals | DC9277 | C-DIM12 >98% | 1g | $900 | 2021-12-16 | Buy |
| Tocris | 5821 | C-DIM12 ≥98%(HPLC) | 10 | $138 | 2021-12-16 | Buy |
Properties
Melting point :76-77 °C
Boiling point :585.6±45.0 °C(Predicted)
Density :1.324±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml)
form :solid
pka :16.40±0.30(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Boiling point :585.6±45.0 °C(Predicted)
Density :1.324±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml)
form :solid
pka :16.40±0.30(Predicted)
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Safety Information
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Description
C-DIM12 is a para-phenyl-substituted diindolylmethane (C-DIM) that is an orally bioavailable activator of nuclear receptor-related protein 1 (Nurr1/NR4A2). It is selective for Nurr1, not activating Nur77, neuron-derived orphan receptor 1 (Nor1), or the retinoid X receptor (RXR) in parallel luciferase assays. C-DIM12 (2.5-10 μM) inhibits proliferation of Ku7 and 253J B-V bladder cancer cells in a dose-dependent manner and induces apoptosis of KU7 cells in a Nurr1-dependent manner. In an orthotopic nude mouse model, C-DIM12 suppresses bladder cancer cell growth by 44 and 59% at doses of 12.5 and 25 mg/kg, respectively. C-DIM12 has neuroprotective properties, preventing dopaminergic cell loss and reducing the expression of NF-κB in the substantia nigra pars compacta in an MPTP mouse model of Parkinson’s disease. It also has analgesic and anti-inflammatory activity in the tail immersion and carrageenan paw edema assays at a dose of 100 mg/kg, without causing ulcers in rats.Related product price
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Suppliers and manufacturers
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