Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt)
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- $202 - $717
- Product name: Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt)
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- MW: 0
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- Synonyms:Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt)
2 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 250μg
- 1mg
- ManufacturerCayman Chemical
- Product number27767
- Product descriptionHistone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt) ≥95%
- Packaging250μg
- Price$202
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27767
- Product descriptionHistone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt) ≥95%
- Packaging1mg
- Price$717
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 27767 | Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt) ≥95% | 250μg | $202 | 2026-04-30 | Buy |
| Cayman Chemical | 27767 | Histone H3K27Me3 (21-44)-GK-biotin (trifluoroacetate salt) ≥95% | 1mg | $717 | 2026-04-30 | Buy |
Properties
solubility :Water: 1 mg/ml
Safety Information
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Description
Histone H3K27Me3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. It is trimethylated at lysine 27 and biotinylated via a C-terminal GK linker. Trimethylation of histone H3 at lysine 27 is associated with gene silencing.1 It is involved in tumor progression through its regulation by enhancer of zeste homolog 2 (EZH2) and transcriptional repression of tumor suppressor genes.2,3 Levels of H3K27Me3 are reduced in 293 T-REx cells containing EEDR236T and SUZ12G610V mutations and in lymphoblastoid cells isolated from patients with Weaver syndrome, a rare overgrowth disorder characterized by EZH2, EED, or SUZ12 mutations, cancer susceptibility, and various distinctive physical features.4 Histone H3K27Me3 (21-44)-GK-biotin has been used as a substrate for histone lysine demethylases (KDMs) to determine substrate specificity.5WARNING This product is not for human or veterinary use.More related product prices