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ChemicalBook >> CAS DataBase List >> PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)

PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 500μg
  • ManufacturerCayman Chemical
  • Product number24771
  • Product descriptionPACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) ≥95%
  • Packaging500μg
  • Price$196
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 24771 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) ≥95% 500μg $196 2026-04-30 Buy

Properties

solubility :Water: 1 mg/ml

Safety Information

Symbol(GHS):
Signal word:
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells.1 It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, SK-N-MC, and T47D cells).2 In vivo, in newborn pigs, PACAP (6-27) (10 μM) inhibits vasodilation of pial arterioles induced by PACAP (1-27) (Item No. 24769) and PACAP (1-38) (Item No. 24770).3 It also inhibits PACAP (1-27)-stimulated increases in plasma insulin and glucagon levels and pancreatic venous blood flow in dogs when administered locally to the pancreas at a dose of 500 μg.4WARNING This product is not for human or veterinary use.

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