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ChemicalBook >> CAS DataBase List >> Amylin (rat, mouse) (trifluoroacetate salt)

Amylin (rat, mouse) (trifluoroacetate salt)

Amylin (rat, mouse) (trifluoroacetate salt) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 500μg
  • ManufacturerCayman Chemical
  • Product number24275
  • Product descriptionAmylin (rat, mouse) (trifluoroacetate salt) ≥95%
  • Packaging500μg
  • Price$321
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 24275 Amylin (rat, mouse) (trifluoroacetate salt) ≥95% 500μg $321 2026-04-30 Buy

Properties

solubility :Water: 1 mg/ml

Safety Information

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Description

Amylin is a 37-residue peptide hormone secreted by pancreatic β-cells that reduces food intake, modifies glycogen synthesis, slows gastric emptying, and increases satiety.1,2,3,4 It binds to heteromeric complexes of human calcitonin receptor 2 (CTR2) with receptor activity-modifying protein (RAMP) 1 or 3 (IC50s = 7.86 and 6.35 nM, respectively).5 It also binds to mouse α-thyroid-stimulating hormone thyrotroph (α-TSH) cells (IC50 = 10.5 nM) and rat nucleus accumbens membrane preparations (Ki = 0.024 nM).4,5 In vitro, amylin (100 nM) inhibits insulin-induced, but not basal, glycogen synthesis in hepatocytes isolated from fasted rats.3 It also inhibits insulin-induced glycogen synthesis ex vivo in isolated soleus muscle from fasted rats.4 In vivo, amylin delays gastric emptying in rats (ED50 = 69 pmol) and decreases food intake in fasted mice (ED50 = 110 μg/kg).2,4 Unlike human amylin (Item No. 24274), rat amylin does not form fibrils and is not cytotoxic.6WARNING This product is not for human or veterinary use.

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