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ChemicalBook >> CAS DataBase List >> MCH (human, mouse, rat) (trifluoroacetate salt)

MCH (human, mouse, rat) (trifluoroacetate salt)

MCH (human, mouse, rat) (trifluoroacetate salt) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 1mg
  • ManufacturerCayman Chemical
  • Product number24462
  • Product descriptionMCH (human, mouse, rat) (trifluoroacetate salt) ≥95%
  • Packaging1mg
  • Price$416
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 24462 MCH (human, mouse, rat) (trifluoroacetate salt) ≥95% 1mg $416 2026-04-30 Buy

Properties

solubility :Water: 1 mg/ml

Safety Information

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Description

Melanin-concentrating hormone (MCH) is an endogenous hypothalamic neuropeptide hormone that is an agonist at MCH receptors.1 It binds to MCH1 and MCH2 receptors (IC50s = 0.17 and 2.9 nM, respectively, for the human receptors) and stimulates calcium accumulation with EC50 values of 28 and 50 nM, respectively, in an aequorin bioluminescence functional assay. MCH also binds to the rat MCH1 receptor (Ki = 0.16 nM in CHO cells), stimulates calcium accumulation (EC50 = 1.79 nM), and inhibits intracellular cAMP accumulation induced by forskolin (Item No. 11018; EC50 = 0.46 nM).2 It binds to mouse MCH receptors on melanoma B16 cells (Ki = 33 nM) and dose-dependently activates the mitogen-activated protein kinase (MAPK) signaling pathway.3 MCH (5 nmol/kg, i.c.v.) increases cumulative food intake in rats.2WARNING This product is not for human or veterinary use.

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