Welcome to chemicalbook!
010-86108875
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> CBL0137 (hydrochloride)

CBL0137 (hydrochloride)

CBL0137 (hydrochloride) price.
  • $45 - $990
  • Product name: CBL0137 (hydrochloride)
  • CAS: 1197397-89-9
  • MF: C21H25ClN2O2
  • MW: 372.89
  • EINECS:
  • MDL Number:
  • Synonyms:CBL0137 (hydrochloride);CBL0137 HCl;CBL0137(CBL-0137);Curaxin-137 hydrochloride;CBL-C137 hydrochloride;1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone,hydrochloride;CBL0137 hydrochloride,Curaxin-137,Nuclear factor-κB,inhibit,Inhibitor,Curaxin137,CBL-C137,Nuclear factor-kappaB,NF-κB,CBL 0137,MDM-2/p53,CBL-0137,CBL-0137 hydrochloride;1,1'-(9-(2-(Isopropylamino)ethyl)-9H-carbazole-3,6-diyl)diethanone hydrochloride
18 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number3371DF
  • Product descriptionCBL0137hydrochloride
  • Packaging5mg
  • Price$634
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3192
  • Product descriptionCBL0137(hydrochloride)
  • Packaging2mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3192
  • Product descriptionCBL0137(hydrochloride)
  • Packaging5mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3192
  • Product descriptionCBL0137(hydrochloride)
  • Packaging10mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19373
  • Product descriptionCBL0137 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19373
  • Product descriptionCBL0137 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$481
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19373
  • Product descriptionCBL0137 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$908
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033711
  • Product descriptionCBL0137hydrochloride 98.67%
  • Packaging2mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033711
  • Product descriptionCBL0137hydrochloride 98.67%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033711
  • Product descriptionCBL0137hydrochloride 98.67%
  • Packaging10mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033711
  • Product descriptionCBL0137hydrochloride 98.67%
  • Packaging25mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033711
  • Product descriptionCBL0137hydrochloride 98.67%
  • Packaging50mg
  • Price$990
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004964
  • Product descriptionCBL0137hydrochloride 99%
  • Packaging2mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004964
  • Product descriptionCBL0137hydrochloride 99%
  • Packaging5mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004964
  • Product descriptionCBL0137hydrochloride 99%
  • Packaging10mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004964
  • Product descriptionCBL0137hydrochloride 99%
  • Packaging25mg
  • Price$447
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3371DF CBL0137hydrochloride 5mg $634 2021-12-16 Buy
ApexBio Technology C3192 CBL0137(hydrochloride) 2mg $70 2021-12-16 Buy
ApexBio Technology C3192 CBL0137(hydrochloride) 5mg $155 2021-12-16 Buy
ApexBio Technology C3192 CBL0137(hydrochloride) 10mg $255 2021-12-16 Buy
Cayman Chemical 19373 CBL0137 (hydrochloride) ≥98% 1mg $109 2024-03-01 Buy
Cayman Chemical 19373 CBL0137 (hydrochloride) ≥98% 5mg $481 2024-03-01 Buy
Cayman Chemical 19373 CBL0137 (hydrochloride) ≥98% 10mg $908 2024-03-01 Buy
ChemScene CS-0033711 CBL0137hydrochloride 98.67% 2mg $70 2021-12-16 Buy
ChemScene CS-0033711 CBL0137hydrochloride 98.67% 5mg $150 2021-12-16 Buy
ChemScene CS-0033711 CBL0137hydrochloride 98.67% 10mg $260 2021-12-16 Buy
ChemScene CS-0033711 CBL0137hydrochloride 98.67% 25mg $560 2021-12-16 Buy
ChemScene CS-0033711 CBL0137hydrochloride 98.67% 50mg $990 2021-12-16 Buy
Crysdot CD31004964 CBL0137hydrochloride 99% 2mg $56 2021-12-16 Buy
Crysdot CD31004964 CBL0137hydrochloride 99% 5mg $121 2021-12-16 Buy
Crysdot CD31004964 CBL0137hydrochloride 99% 10mg $208 2021-12-16 Buy
Crysdot CD31004964 CBL0137hydrochloride 99% 25mg $447 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :insoluble in EtOH; ≥15.47 mg/mL in H2O; ≥19.95 mg/mL in DMSO
form :crystalline solid
color :Off-white to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Curaxins are small molecules that simultaneously activate p53 and inhibit NF-κB without causing detectable genotoxicity. CBL0137 is a water soluble and metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 value of 0.47 μM. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death. CBL0137 has broad anticancer activity in mice when administered orally, eradicates drug-resistant cancer stem cells, and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer.