CBR-5884
- $32 - $1504.5
- Product name: CBR-5884
- CAS: 681159-27-3
- MF: C14H12N2O4S2
- MW: 336.39
- EINECS:
- MDL Number:MFCD04451442
- Synonyms:CBR-5884;Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate;CBR 5884;CBR5884;ethyl 4-(cyanosulfanyl)-5-(furan-2-amido)-3-methylthiophene-2-carboxylate;2-Thiophenecarboxylic acid, 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-, ethyl ester;CBR 5884,inhibit,CBR-5884,Inhibitor,CBR5884;Ethyl 5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
28 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number0874CN
- Product descriptionEthyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0874CN
- Product descriptionEthyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8721
- Product descriptionCBR-5884
- Packaging5mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8721
- Product descriptionCBR-5884
- Packaging10mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8721
- Product descriptionCBR-5884
- Packaging25mg
- Price$221
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8721
- Product descriptionCBR-5884
- Packaging50mg
- Price$389
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8721
- Product descriptionCBR-5884
- Packaging100mg
- Price$693
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2585
- Product descriptionCBR5884 99%
- Packaging10mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545924
- Product descriptionCbR-5884 >98%
- Packaging5mg
- Price$190.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611634
- Product descriptionCBR-5884
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545924
- Product descriptionCbR-5884 >98%
- Packaging25mg
- Price$521.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611634
- Product descriptionCBR-5884
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611634
- Product descriptionCBR-5884
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19236
- Product descriptionCBR-5884 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19236
- Product descriptionCBR-5884 ≥98%
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19236
- Product descriptionCBR-5884 ≥98%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 0874CN | Ethyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate | 1mg | $133 | 2021-12-16 | Buy |
AK Scientific | 0874CN | Ethyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate | 10mg | $268 | 2021-12-16 | Buy |
ApexBio Technology | A8721 | CBR-5884 | 5mg | $63 | 2021-12-16 | Buy |
ApexBio Technology | A8721 | CBR-5884 | 10mg | $105 | 2021-12-16 | Buy |
ApexBio Technology | A8721 | CBR-5884 | 25mg | $221 | 2021-12-16 | Buy |
ApexBio Technology | A8721 | CBR-5884 | 50mg | $389 | 2021-12-16 | Buy |
ApexBio Technology | A8721 | CBR-5884 | 100mg | $693 | 2021-12-16 | Buy |
Axon Medchem | Axon2585 | CBR5884 99% | 10mg | $99 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545924 | CbR-5884 >98% | 5mg | $190.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611634 | CBR-5884 | 100mg | $510 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545924 | CbR-5884 >98% | 25mg | $521.9 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611634 | CBR-5884 | 250mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611634 | CBR-5884 | 1g | $1504.5 | 2021-12-16 | Buy |
Cayman Chemical | 19236 | CBR-5884 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 19236 | CBR-5884 ≥98% | 5mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 19236 | CBR-5884 ≥98% | 10mg | $153 | 2024-03-01 | Buy |
Properties
Boiling point :378.1±42.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.25±0.70(Predicted)
form :paste
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.25±0.70(Predicted)
form :paste
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 μM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of cancer cells by blocking de novo serine synthesis and is selectively cytotoxic for cells with high serine biosynthetic activity.Related product price
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Suppliers and manufacturers
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Sigma-Aldrich
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