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ChemicalBook >> CAS DataBase List >> CBR-5884

CBR-5884

CBR-5884 price.
  • $32 - $1504.5
  • Product name: CBR-5884
  • CAS: 681159-27-3
  • MF: C14H12N2O4S2
  • MW: 336.39
  • EINECS:
  • MDL Number:MFCD04451442
  • Synonyms:CBR-5884;Ethyl 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylate;CBR 5884;CBR5884;ethyl 4-(cyanosulfanyl)-5-(furan-2-amido)-3-methylthiophene-2-carboxylate;2-Thiophenecarboxylic acid, 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-, ethyl ester;CBR 5884,inhibit,CBR-5884,Inhibitor,CBR5884;Ethyl 5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
28 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0874CN
  • Product descriptionEthyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0874CN
  • Product descriptionEthyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8721
  • Product descriptionCBR-5884
  • Packaging5mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8721
  • Product descriptionCBR-5884
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8721
  • Product descriptionCBR-5884
  • Packaging25mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8721
  • Product descriptionCBR-5884
  • Packaging50mg
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8721
  • Product descriptionCBR-5884
  • Packaging100mg
  • Price$693
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2585
  • Product descriptionCBR5884 99%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545924
  • Product descriptionCbR-5884 >98%
  • Packaging5mg
  • Price$190.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611634
  • Product descriptionCBR-5884
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545924
  • Product descriptionCbR-5884 >98%
  • Packaging25mg
  • Price$521.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611634
  • Product descriptionCBR-5884
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611634
  • Product descriptionCBR-5884
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19236
  • Product descriptionCBR-5884 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19236
  • Product descriptionCBR-5884 ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19236
  • Product descriptionCBR-5884 ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0874CN Ethyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate 1mg $133 2021-12-16 Buy
AK Scientific 0874CN Ethyl5-(furan-2-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate 10mg $268 2021-12-16 Buy
ApexBio Technology A8721 CBR-5884 5mg $63 2021-12-16 Buy
ApexBio Technology A8721 CBR-5884 10mg $105 2021-12-16 Buy
ApexBio Technology A8721 CBR-5884 25mg $221 2021-12-16 Buy
ApexBio Technology A8721 CBR-5884 50mg $389 2021-12-16 Buy
ApexBio Technology A8721 CBR-5884 100mg $693 2021-12-16 Buy
Axon Medchem Axon2585 CBR5884 99% 10mg $99 2021-12-16 Buy
Biorbyt Ltd orb545924 CbR-5884 >98% 5mg $190.4 2021-12-16 Buy
Biorbyt Ltd orb611634 CBR-5884 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb545924 CbR-5884 >98% 25mg $521.9 2021-12-16 Buy
Biorbyt Ltd orb611634 CBR-5884 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb611634 CBR-5884 1g $1504.5 2021-12-16 Buy
Cayman Chemical 19236 CBR-5884 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 19236 CBR-5884 ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 19236 CBR-5884 ≥98% 10mg $153 2024-03-01 Buy

Properties

Boiling point :378.1±42.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in DMF (up to 50 mg/ml).
pka :11.25±0.70(Predicted)
form :paste
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 μM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of cancer cells by blocking de novo serine synthesis and is selectively cytotoxic for cells with high serine biosynthetic activity.

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