CEP-40783
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- $29 - $3450
- Product name: CEP-40783
- CAS: 1437321-24-8
- MF: C31H26F2N4O6
- MW: 588.56
- EINECS:
- MDL Number:MFCD28502441
- Synonyms:CEP-40783;CEP-40783(RXDX-106);3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid [4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluorophenyl]amide;CEP 40783; CEP40783; RXDX-106;RXDX-106(CEP-40783);CS-2528;5-Pyrimidinecarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-3-fluorophenyl]-3-(4-fluorophenyl)-1,2,3,4-tetrahydro-1-(1-methylethyl)-2,4-dioxo-;N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
39 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98%
- Packaging2mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98
- Packaging5mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98
- Packaging10mg
- Price$61
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98%
- Packaging1mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98
- Packaging25mg
- Price$117
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98
- Packaging50mg
- Price$144
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001I7L
- Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98
- Packaging100mg
- Price$199
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22064
- Product descriptionCEP-40783 98%
- Packaging25MG
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22064
- Product descriptionCEP-40783 98%
- Packaging100MG
- Price$685
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22064
- Product descriptionCEP-40783 98%
- Packaging1G
- Price$3450
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9397DU
- Product descriptionN-[4-(6,7-Dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
- Packaging25mg
- Price$785
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-100946
- Product descriptionCEP-40783 99.61%
- Packaging1g
- Price$2518
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100946
- Product descriptionCEP-40783 99.61%
- Packaging100mg
- Price$618
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100946
- Product descriptionCEP-40783 99.61%
- Packaging50mg
- Price$428
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8570
- Product descriptionRXDX-106 (CEP-40783) 99.57%
- Packaging25mg
- Price$492
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100946
- Product descriptionCEP-40783 99.61%
- Packaging200mg
- Price$903
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98% | 2mg | $44 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98 | 5mg | $44 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98 | 10mg | $61 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98% | 1mg | $29 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98 | 25mg | $117 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98 | 50mg | $144 | 2026-05-28 | Buy |
| aablocks | AA001I7L | N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide 98 | 100mg | $199 | 2026-05-28 | Buy |
| ACHEMBLOCK | L22064 | CEP-40783 98% | 25MG | $245 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22064 | CEP-40783 98% | 100MG | $685 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22064 | CEP-40783 98% | 1G | $3450 | 2026-05-27 | Buy |
| AK Scientific | 9397DU | N-[4-(6,7-Dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide | 25mg | $785 | 2021-12-16 | Buy |
| Arctom | HY-100946 | CEP-40783 99.61% | 1g | $2518 | 2026-05-26 | Buy |
| Arctom | HY-100946 | CEP-40783 99.61% | 100mg | $618 | 2026-05-26 | Buy |
| Arctom | HY-100946 | CEP-40783 99.61% | 50mg | $428 | 2026-05-26 | Buy |
| Arctom | SLK-S8570 | RXDX-106 (CEP-40783) 99.57% | 25mg | $492 | 2026-05-26 | Buy |
| Arctom | HY-100946 | CEP-40783 99.61% | 200mg | $903 | 2026-05-26 | Buy |
Properties
Density :1.394±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);33.89(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.51(Max Conc. mM)
DMSO:6.04(Max Conc. mg/mL);10.26(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);3.4(Max Conc. mM) form :A crystalline solid
pka :10.42±0.70(Predicted)
color :White to off-white
InChIKey :FKCWHHYUMFGOPY-UHFFFAOYSA-N
SMILES :C1(=O)N(C(C)C)C=C(C(NC2=CC=C(OC3C4C(N=CC=3)=CC(OC)=C(OC)C=4)C(F)=C2)=O)C(=O)N1C1=CC=C(F)C=C1
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);33.89(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.51(Max Conc. mM)
DMSO:6.04(Max Conc. mg/mL);10.26(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);3.4(Max Conc. mM) form :A crystalline solid
pka :10.42±0.70(Predicted)
color :White to off-white
InChIKey :FKCWHHYUMFGOPY-UHFFFAOYSA-N
SMILES :C1(=O)N(C(C)C)C=C(C(NC2=CC=C(OC3C4C(N=CC=3)=CC(OC)=C(OC)C=4)C(F)=C2)=O)C(=O)N1C1=CC=C(F)C=C1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
CEP-40783 is a potent, selective and orally potent inhibitor of axl and c-Met with IC50 values of 7nM and 12nM, respectively.Related product price
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