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ChemicalBook >> CAS DataBase List >> CID5721353

CID5721353

CID5721353 price.
  • $19 - $1800
  • Product name: CID5721353
  • CAS: 301356-95-6
  • MF: C15H9BrN2O6S2
  • MW: 457.28
  • EINECS:
  • MDL Number:MFCD31729277
  • Synonyms:CID5721353;CID5721353, BCL6 inhibitor;BCL6 inhibitor(CID5721353);CID5721353 BDL6 inhribitor;CID-5721353;CID 5721353;79-6 (CID5721353, BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid
44 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 2mg
  • 5mg
  • 1mL(10mMinDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging10mg
  • Price$61
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging25mg
  • Price$98
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging50mg
  • Price$164
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging100mg
  • Price$247
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging5mg
  • Price$41
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging2mg
  • Price$23
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01ENT9
  • Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
  • Packaging1mg
  • Price$19
  • Updated2026-05-30
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  • ManufacturerACHEMBLOCK
  • Product numberQ70219
  • Product descriptionCID5721353 98%
  • Packaging100MG
  • Price$245
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ70219
  • Product descriptionCID5721353 98%
  • Packaging1G
  • Price$1225
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number6486CL
  • Product description2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
  • Packaging5mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6486CL
  • Product description2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberBA3075
  • Product descriptionCID5721353
  • Packaging10mg
  • Price$135
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3075
  • Product descriptionCID5721353
  • Packaging1mL(10mMinDMSO)
  • Price$81
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3075
  • Product descriptionCID5721353
  • Packaging5mg
  • Price$81
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3075
  • Product descriptionCID5721353
  • Packaging25mg
  • Price$261
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3075
  • Product descriptionCID5721353
  • Packaging50mg
  • Price$441
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 10mg $61 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 25mg $98 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 50mg $164 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 100mg $247 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 5mg $41 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 2mg $23 2026-05-30 Buy
aablocks AA01ENT9 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% 1mg $19 2026-05-30 Buy
ACHEMBLOCK Q70219 CID5721353 98% 100MG $245 2026-05-27 Buy
ACHEMBLOCK Q70219 CID5721353 98% 1G $1225 2026-05-27 Buy
AK Scientific 6486CL 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid 5mg $313 2021-12-16 Buy
AK Scientific 6486CL 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid 1mg $147 2021-12-16 Buy
ApexBio Technology BA3075 CID5721353 10mg $135 2026-05-06 Buy
ApexBio Technology BA3075 CID5721353 1mL(10mMinDMSO) $81 2026-05-06 Buy
ApexBio Technology BA3075 CID5721353 5mg $81 2026-05-06 Buy
ApexBio Technology BA3075 CID5721353 25mg $261 2026-05-06 Buy
ApexBio Technology BA3075 CID5721353 50mg $441 2026-05-06 Buy

Properties

Density :2.06±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Solid
pka :3.02±0.23(Predicted)
color :Light brown to brown

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; Ki = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI50s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI50 = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.