CID5721353
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- $19 - $1800
- Product name: CID5721353
- CAS: 301356-95-6
- MF: C15H9BrN2O6S2
- MW: 457.28
- EINECS:
- MDL Number:MFCD31729277
- Synonyms:CID5721353;CID5721353, BCL6 inhibitor;BCL6 inhibitor(CID5721353);CID5721353 BDL6 inhribitor;CID-5721353;CID 5721353;79-6 (CID5721353, BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid
44 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 2mg
- 5mg
- 1mL(10mMinDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging10mg
- Price$61
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging25mg
- Price$98
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging50mg
- Price$164
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging100mg
- Price$247
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging5mg
- Price$41
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging2mg
- Price$23
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01ENT9
- Product description2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98%
- Packaging1mg
- Price$19
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70219
- Product descriptionCID5721353 98%
- Packaging100MG
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70219
- Product descriptionCID5721353 98%
- Packaging1G
- Price$1225
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number6486CL
- Product description2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
- Packaging5mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6486CL
- Product description2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA3075
- Product descriptionCID5721353
- Packaging10mg
- Price$135
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3075
- Product descriptionCID5721353
- Packaging1mL(10mMinDMSO)
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3075
- Product descriptionCID5721353
- Packaging5mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3075
- Product descriptionCID5721353
- Packaging25mg
- Price$261
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA3075
- Product descriptionCID5721353
- Packaging50mg
- Price$441
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 10mg | $61 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 25mg | $98 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 50mg | $164 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 100mg | $247 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 5mg | $41 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 2mg | $23 | 2026-05-30 | Buy |
| aablocks | AA01ENT9 | 2-[5-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]butanedioic acid 98% | 1mg | $19 | 2026-05-30 | Buy |
| ACHEMBLOCK | Q70219 | CID5721353 98% | 100MG | $245 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70219 | CID5721353 98% | 1G | $1225 | 2026-05-27 | Buy |
| AK Scientific | 6486CL | 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid | 5mg | $313 | 2021-12-16 | Buy |
| AK Scientific | 6486CL | 2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid | 1mg | $147 | 2021-12-16 | Buy |
| ApexBio Technology | BA3075 | CID5721353 | 10mg | $135 | 2026-05-06 | Buy |
| ApexBio Technology | BA3075 | CID5721353 | 1mL(10mMinDMSO) | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA3075 | CID5721353 | 5mg | $81 | 2026-05-06 | Buy |
| ApexBio Technology | BA3075 | CID5721353 | 25mg | $261 | 2026-05-06 | Buy |
| ApexBio Technology | BA3075 | CID5721353 | 50mg | $441 | 2026-05-06 | Buy |
Properties
Density :2.06±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Solid
pka :3.02±0.23(Predicted)
color :Light brown to brown
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Solid
pka :3.02±0.23(Predicted)
color :Light brown to brown
Safety Information
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Description
CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; Ki = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI50s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI50 = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.More related product prices
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