CITCO
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- $20 - $2200
- Product name: CITCO
- CAS: 338404-52-7
- MF: C19H12Cl3N3OS
- MW: 436.74
- EINECS:
- MDL Number:MFCD00139608
- Synonyms:Imidazo[2,1-b]thiazole-5-carboxaldehyde, 6-(4-chlorophenyl)-, O-[(3,4-dichlorophenyl)methyl]oxime;6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime;CITCO,Inhibitor,inhibit,Apoptosis;CITCO, 10 mM in DMSO
48 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5mg
- 1mlx10mM(inDMSO)
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime ≥98%(HPLC)
- Packaging5mg
- Price$20
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime ≥98%(HPLC)
- Packaging10mg
- Price$35
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98%
- Packaging25mg
- Price$61
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98%
- Packaging50mg
- Price$103
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98%
- Packaging100mg
- Price$174
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00CN7O
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98%
- Packaging250mg
- Price$348
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203421
- Product descriptionCITCO 98.00%
- Packaging100MG
- Price$225
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203421
- Product descriptionCITCO 98.00%
- Packaging250MG
- Price$545
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203421
- Product descriptionCITCO 98.00%
- Packaging1G
- Price$1635
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3614BB
- Product descriptionCitco
- Packaging10mg
- Price$248
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1167756
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1167756
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
- Packaging25mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1167756
- Product description6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98%
- Packaging100mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008469
- Product descriptionCITCO 95.00%
- Packaging10MG
- Price$660.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008469
- Product descriptionCITCO 95.00%
- Packaging50MG
- Price$1041.76
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008469
- Product descriptionCITCO 95.00%
- Packaging5MG
- Price$184.8
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime ≥98%(HPLC) | 5mg | $20 | 2026-05-28 | Buy |
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime ≥98%(HPLC) | 10mg | $35 | 2026-05-28 | Buy |
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98% | 25mg | $61 | 2026-05-28 | Buy |
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98% | 50mg | $103 | 2026-05-28 | Buy |
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98% | 100mg | $174 | 2026-05-28 | Buy |
| aablocks | AA00CN7O | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime 98% | 250mg | $348 | 2026-05-28 | Buy |
| ACHEMBLOCK | X203421 | CITCO 98.00% | 100MG | $225 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203421 | CITCO 98.00% | 250MG | $545 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203421 | CITCO 98.00% | 1G | $1635 | 2026-05-27 | Buy |
| AK Scientific | 3614BB | Citco | 10mg | $248 | 2021-12-16 | Buy |
| Ambeed | A1167756 | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% | 50mg | $200 | 2021-12-16 | Buy |
| Ambeed | A1167756 | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% | 25mg | $122 | 2021-12-16 | Buy |
| Ambeed | A1167756 | 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehydeO-(3,4-dichlorobenzyl)oxime 98% | 100mg | $280 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008469 | CITCO 95.00% | 10MG | $660.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008469 | CITCO 95.00% | 50MG | $1041.76 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008469 | CITCO 95.00% | 5MG | $184.8 | 2021-12-16 | Buy |
Properties
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 28 mg/mL, soluble
form :solid
pka :4.05±0.40(Predicted)
color :Light yellow to yellow
InChI :1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2/b23-10+
InChIKey :ZQWBOKJVVYNKTL-AUEPDCJTSA-N
SMILES :Clc1ccc(cc1)-c2nc3sccn3c2\C=N\OCc4ccc(Cl)c(Cl)c4
storage temp. :-20°C
solubility :DMSO: 28 mg/mL, soluble
form :solid
pka :4.05±0.40(Predicted)
color :Light yellow to yellow
InChI :1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2/b23-10+
InChIKey :ZQWBOKJVVYNKTL-AUEPDCJTSA-N
SMILES :Clc1ccc(cc1)-c2nc3sccn3c2\C=N\OCc4ccc(Cl)c(Cl)c4
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
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Description
The constitutive androstane receptor (CAR) is a nuclear receptor that functions as a sensor of toxic compounds and enhances their elimination. CITCO is an agonist of human CAR (EC50 = 49 nM). It induces nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. CITCO less potently activates human pregnane X receptor (EC50 = 3 μM) and has no detectable activity on other nuclear receptors at 10 μM. It is selective for human CAR, whereas TCPOBOP is selective for mouse CAR. CITCO does activate alternative splice variants of human CAR that are also found in liver cells. It is commonly used to study the action of human CAR in hepatocytes.Related product price
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