(-)-COTININE
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- $27.7 - $2083
- Product name: (-)-COTININE
- CAS: 486-56-6
- MF: C10H12N2O
- MW: 176.22
- EINECS:207-634-9
- MDL Number:MFCD00077696
- Synonyms:L-COTININE;(-)-COTININE;(S)-(-)-1-METHYL-5-(3-PYRIDIYL)-2-PYRROLIDINONE;[S]-1-METHYL-5-[3-PYRIDYL]-2-PYRROLIDINONE;S(-)-1-METHYL-5-(3-PYRIDYL)-2-PYRROLIDONE;(s)-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone ;(s)-2-pyrrolidinon ;1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
36 prices
Selected condition：
Brand
- ACHEMBLOCK
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- Matrix Scientific
- Sigma-Aldrich
- SynQuest Laboratories
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500ul
- 500mg
- 1g
- 1mL
- 10mM(in 1mL DMSO)
- 2g
- 5G
- ManufacturerACHEMBLOCK
- Product numberG-5334
- Product description(-)-Cotinine 97%
- Packaging5G
- Price$2083
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberL11873
- Product description(-)-Cotinine, 98%
- Packaging250mg
- Price$78.4
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberL11873
- Product description(-)-Cotinine, 98%
- Packaging1g
- Price$186
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging50mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging100mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA431146
- Product description(S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+%
- Packaging250mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7277
- Product description(-)-Cotinine
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7277
- Product description(-)-Cotinine
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20565
- Product descriptionS-(-)-Cotinine
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20565
- Product descriptionS-(-)-Cotinine
- Packaging250mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20565
- Product descriptionS-(-)-Cotinine
- Packaging500mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20565
- Product descriptionS-(-)-Cotinine
- Packaging1g
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC20565
- Product descriptionS-(-)-Cotinine
- Packaging2g
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15314
- Product description(-)-Cotinine ≥98%
- Packaging50mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15314
- Product description(-)-Cotinine ≥98%
- Packaging100mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15314
- Product description(-)-Cotinine ≥98%
- Packaging250mg
- Price$92
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | G-5334 | (-)-Cotinine 97% | 5G | $2083 | 2021-12-16 | Buy |
| Alfa Aesar | L11873 | (-)-Cotinine, 98% | 250mg | $78.4 | 2024-03-01 | Buy |
| Alfa Aesar | L11873 | (-)-Cotinine, 98% | 1g | $186 | 2024-03-01 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 50mg | $42 | 2021-12-16 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 100mg | $76 | 2021-12-16 | Buy |
| Ambeed | A431146 | (S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one 98+% | 250mg | $114 | 2021-12-16 | Buy |
| ApexBio Technology | B7277 | (-)-Cotinine | 50mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B7277 | (-)-Cotinine | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20565 | S-(-)-Cotinine | 100mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20565 | S-(-)-Cotinine | 250mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20565 | S-(-)-Cotinine | 500mg | $160 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20565 | S-(-)-Cotinine | 1g | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20565 | S-(-)-Cotinine | 2g | $450 | 2021-12-16 | Buy |
| Cayman Chemical | 15314 | (-)-Cotinine ≥98% | 50mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 15314 | (-)-Cotinine ≥98% | 100mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 15314 | (-)-Cotinine ≥98% | 250mg | $92 | 2024-03-01 | Buy |
Properties
Melting point :40-42 °C(lit.)
Boiling point :250 °C150 mm Hg(lit.)
alpha :[α]D20 -18～-22° (c=1, C2H5OH)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
EPA Substance Registry System :Cotinine (486-56-6)
Boiling point :250 °C150 mm Hg(lit.)
alpha :[α]D20 -18～-22° (c=1, C2H5OH)
Density :1.1102 (rough estimate)
refractive index :1.7110 (estimate)
Flash point :>230 °F
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
form :Solid
pka :4.72±0.12(Predicted)
color :Colourless to Very Dark Orange Oil
optical activity :[α]/D -21±2°, c = 1 in ethanol
Water Solubility :Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.
Merck :14,2553
BRN :83099
Stability :Stable. Incompatible with strong oxidizing agents. May be heat sensitive - store cold.
EPA Substance Registry System :Cotinine (486-56-6)
Safety Information
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Description
Cotinine is a minor alkaloid found in tobacco plants and is a major metabolite of nicotine. It has a long pharmacological half-life (15-19 hours) compared to that of nicotine (2-3 hours) and is often used as a biomarker to detect tobacco use. Cotinine binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.Related product price
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