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ChemicalBook >> CAS DataBase List >> CP-547632

CP-547632

CP-547632 price.
  • $27 - $6683
  • Product name: CP-547632
  • CAS: 252003-65-9
  • MF: C20H24BrF2N5O3S
  • MW: 532.4
  • EINECS:200-258-5
  • MDL Number:MFCD07772279
  • Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
Price38 Properties Safety Information Description
38 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250.00mg
  • 250mg
  • 500MG
  • 1g
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging1mg
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging5mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging10mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging25mg
  • Price$128
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging50mg
  • Price$158
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging1g
  • Price$2552
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226011
  • Product descriptionCP-547632 97.00%
  • Packaging100MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226011
  • Product descriptionCP-547632 97.00%
  • Packaging50MG
  • Price$255
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5494
  • Product description3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide
  • Packaging250mg
  • Price$6683
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging50mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging10mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging25mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005167
  • Product descriptionCP-547632 95.00%
  • Packaging500MG
  • Price$4966.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1662
  • Product descriptionCP 547632
  • Packaging2mg
  • Price$77
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1662
  • Product descriptionCP 547632
  • Packaging5mg
  • Price$121
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002QST CP 547,632 95% 1mg $27 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 5mg $49 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 10mg $63 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 25mg $128 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 50mg $158 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 1g $2552 2026-05-28 Buy
ACHEMBLOCK Y226011 CP-547632 97.00% 100MG $550 2026-05-27 Buy
ACHEMBLOCK Y226011 CP-547632 97.00% 50MG $255 2026-05-27 Buy
AK Scientific X5494 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide 250mg $6683 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 50mg $284 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 10mg $137 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 25mg $179 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 5mg $105 2021-12-16 Buy
American Custom Chemicals Corporation API0005167 CP-547632 95.00% 500MG $4966.5 2021-12-16 Buy
Axon Medchem Axon1662 CP 547632 2mg $77 2026-05-19 Buy
Axon Medchem Axon1662 CP 547632 5mg $121 2026-05-19 Buy
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Properties

Boiling point :548.6±50.0 °C(Predicted)
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
InChIKey :HXHAJRMTJXHJJZ-UHFFFAOYSA-N
SMILES :S1C(NC(NCCCCN2CCCC2)=O)=C(C(N)=O)C(OCC2=C(F)C=C(Br)C=C2F)=N1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.

Description

CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.

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Suppliers and manufacturers

Hangzhou FuRun Pharmaceutical Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited China Kouting Group Limited China Nobel Chem Co., Limited Guangzhou Isun Pharmaceutical Co., Ltd AdooQ BioScience, LLC Tianjin Anhao Biological Technology Co., Ltd. Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Shanghai Tombiopharma Chemical Co. Ltd.