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ChemicalBook >> CAS DataBase List >> CP-547632

CP-547632

CP-547632 price.
  • $27 - $6683
  • Product name: CP-547632
  • CAS: 252003-65-9
  • MF: C20H24BrF2N5O3S
  • MW: 532.4
  • EINECS:200-258-5
  • MDL Number:MFCD07772279
  • Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
38 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250.00mg
  • 250mg
  • 500MG
  • 1g
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging1mg
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging5mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging10mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging25mg
  • Price$128
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging50mg
  • Price$158
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002QST
  • Product descriptionCP 547,632 95%
  • Packaging1g
  • Price$2552
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226011
  • Product descriptionCP-547632 97.00%
  • Packaging100MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226011
  • Product descriptionCP-547632 97.00%
  • Packaging50MG
  • Price$255
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5494
  • Product description3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide
  • Packaging250mg
  • Price$6683
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging10mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging25mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA867793
  • Product descriptionCp-547632 95%
  • Packaging50mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005167
  • Product descriptionCP-547632 95.00%
  • Packaging500MG
  • Price$4966.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1662
  • Product descriptionCP 547632
  • Packaging25mg
  • Price$396
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1662
  • Product descriptionCP 547632
  • Packaging2mg
  • Price$77
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002QST CP 547,632 95% 1mg $27 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 5mg $49 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 10mg $63 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 25mg $128 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 50mg $158 2026-05-28 Buy
aablocks AA002QST CP 547,632 95% 1g $2552 2026-05-28 Buy
ACHEMBLOCK Y226011 CP-547632 97.00% 100MG $550 2026-05-27 Buy
ACHEMBLOCK Y226011 CP-547632 97.00% 50MG $255 2026-05-27 Buy
AK Scientific X5494 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide 250mg $6683 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 5mg $105 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 10mg $137 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 25mg $179 2021-12-16 Buy
Ambeed A867793 Cp-547632 95% 50mg $284 2021-12-16 Buy
American Custom Chemicals Corporation API0005167 CP-547632 95.00% 500MG $4966.5 2021-12-16 Buy
Axon Medchem Axon1662 CP 547632 25mg $396 2026-05-19 Buy
Axon Medchem Axon1662 CP 547632 2mg $77 2026-05-19 Buy

Properties

Boiling point :548.6±50.0 °C(Predicted)
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
InChIKey :HXHAJRMTJXHJJZ-UHFFFAOYSA-N
SMILES :S1C(NC(NCCCCN2CCCC2)=O)=C(C(N)=O)C(OCC2=C(F)C=C(Br)C=C2F)=N1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.

Description

CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.

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