CP-547632
|
- $27 - $6683
- Product name: CP-547632
- CAS: 252003-65-9
- MF: C20H24BrF2N5O3S
- MW: 532.4
- EINECS:200-258-5
- MDL Number:MFCD07772279
- Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
38 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 500μg
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250.00mg
- 250mg
- 500MG
- 1g
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging1mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging5mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging10mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging25mg
- Price$128
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging50mg
- Price$158
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QST
- Product descriptionCP 547,632 95%
- Packaging1g
- Price$2552
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226011
- Product descriptionCP-547632 97.00%
- Packaging100MG
- Price$550
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226011
- Product descriptionCP-547632 97.00%
- Packaging50MG
- Price$255
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX5494
- Product description3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide
- Packaging250mg
- Price$6683
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging25mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging50mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005167
- Product descriptionCP-547632 95.00%
- Packaging500MG
- Price$4966.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1662
- Product descriptionCP 547632
- Packaging25mg
- Price$396
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1662
- Product descriptionCP 547632
- Packaging2mg
- Price$77
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002QST | CP 547,632 95% | 1mg | $27 | 2026-05-28 | Buy |
| aablocks | AA002QST | CP 547,632 95% | 5mg | $49 | 2026-05-28 | Buy |
| aablocks | AA002QST | CP 547,632 95% | 10mg | $63 | 2026-05-28 | Buy |
| aablocks | AA002QST | CP 547,632 95% | 25mg | $128 | 2026-05-28 | Buy |
| aablocks | AA002QST | CP 547,632 95% | 50mg | $158 | 2026-05-28 | Buy |
| aablocks | AA002QST | CP 547,632 95% | 1g | $2552 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y226011 | CP-547632 97.00% | 100MG | $550 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226011 | CP-547632 97.00% | 50MG | $255 | 2026-05-27 | Buy |
| AK Scientific | X5494 | 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide | 250mg | $6683 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 5mg | $105 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 10mg | $137 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 25mg | $179 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 50mg | $284 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005167 | CP-547632 95.00% | 500MG | $4966.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon1662 | CP 547632 | 25mg | $396 | 2026-05-19 | Buy |
| Axon Medchem | Axon1662 | CP 547632 | 2mg | $77 | 2026-05-19 | Buy |
Properties
Boiling point :548.6±50.0 °C(Predicted)
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
InChIKey :HXHAJRMTJXHJJZ-UHFFFAOYSA-N
SMILES :S1C(NC(NCCCCN2CCCC2)=O)=C(C(N)=O)C(OCC2=C(F)C=C(Br)C=C2F)=N1
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
InChIKey :HXHAJRMTJXHJJZ-UHFFFAOYSA-N
SMILES :S1C(NC(NCCCCN2CCCC2)=O)=C(C(N)=O)C(OCC2=C(F)C=C(Br)C=C2F)=N1
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.Related product price
-
PENTAFLUOROBENZYL BROMIDE
$10-2506.47 -
942655-44-9
$35-2188 -
343787-29-1
$16-2691.1
Suppliers and manufacturers
Shaanxi Dideu New Materials Co. Ltd
CONIER CHEM AND PHARMA LIMITED
BOC Sciences
Amadis Chemical Company Limited
Chembest Research Laboratories Limited
Guangzhou Isun Pharmaceutical Co., Ltd
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
CP-547632
CAS:252003-65-9




