CUR 61414
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- $90 - $7645
- Product name: CUR 61414
- CAS: 334998-36-6
- MF: C31H42N4O5
- MW: 550.69
- EINECS:
- MDL Number:MFCD20275055
- Synonyms:CUR 61414;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-benzamide;N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;Butanamide, N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-;CUR61414,CUR-61414;CUR 61414, Hedgehog signaling pathway antagonist;CUR61414, 10 mM in DMSO
39 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 25MG
- 50mg
- 250mg
- 500mg
- 10mM*1mLinDMSO(Solution)
- 2mg
- 10mg
- 100MG
- 5mg
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerACHEMBLOCK
- Product numberY226621
- Product descriptionCUR61414 97.00%
- Packaging25MG
- Price$435
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226621
- Product descriptionCUR61414 97.00%
- Packaging100MG
- Price$980
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number7204CR
- Product descriptionN-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
- Packaging5mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5138
- Product descriptionCUR 61414
- Packaging10mg
- Price$316
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5138
- Product descriptionCUR 61414
- Packaging5mg
- Price$192
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging10mg
- Price$209
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$151
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging10mM*1mLinDMSO(Solution)
- Price$158
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging5mg
- Price$131
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging25mg
- Price$418
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging100mg
- Price$941
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-113965
- Product descriptionCUR61414 99.04%
- Packaging50mg
- Price$627
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6237
- Product descriptionCUR61414 98%
- Packaging25mg
- Price$360
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6237
- Product descriptionCUR61414 98%
- Packaging5mg
- Price$90
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberFB20593
- Product descriptionCUR 61414
- Packaging10mg
- Price$337.4
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFB20593
- Product descriptionCUR 61414
- Packaging50mg
- Price$1180.5
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y226621 | CUR61414 97.00% | 25MG | $435 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226621 | CUR61414 97.00% | 100MG | $980 | 2026-05-27 | Buy |
| AK Scientific | 7204CR | N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide | 5mg | $232 | 2021-12-16 | Buy |
| ApexBio Technology | C5138 | CUR 61414 | 10mg | $316 | 2026-05-06 | Buy |
| ApexBio Technology | C5138 | CUR 61414 | 5mg | $192 | 2026-05-06 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 10mg | $209 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 10mM*1mLinDMSO(Solid+Solvent) | $151 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 10mM*1mLinDMSO(Solution) | $158 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 5mg | $131 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 25mg | $418 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 100mg | $941 | 2026-05-26 | Buy |
| Arctom | HY-113965 | CUR61414 99.04% | 50mg | $627 | 2026-05-26 | Buy |
| AvaChem | 6237 | CUR61414 98% | 25mg | $360 | 2026-05-22 | Buy |
| AvaChem | 6237 | CUR61414 98% | 5mg | $90 | 2026-05-22 | Buy |
| Biosynth | FB20593 | CUR 61414 | 10mg | $337.4 | 2026-06-04 | Buy |
| Biosynth | FB20593 | CUR 61414 | 50mg | $1180.5 | 2026-06-04 | Buy |
Properties
Melting point :35-40°C
Boiling point :714.1±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble2mg/mL (clear solution, warmed)
pka :8.42±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Boiling point :714.1±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble2mg/mL (clear solution, warmed)
pka :8.42±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
CUR 61414 is a potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM). It binds directly with the pathway activator Smoothened (Ki = 44 nM). CUR 61414 blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in mouse skin.Related product price
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
Chemsky（shanghai）International Co.,Ltd.
Shanghai TaoSu Biochemical Technology Co., Ltd.
Shanghai Rechem science Co., Ltd.
Shanghai Han-Xiang Chemical Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.
BOC Sciences
TargetMol Chemicals Inc.
VladaChem GmbH
Jinan ponder chemical co. LTD