CUR 61414
- $120 - $1880
- Product name: CUR 61414
- CAS: 334998-36-6
- MF: C31H42N4O5
- MW: 550.69
- EINECS:
- MDL Number:MFCD20275055
- Synonyms:CUR 61414;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-benzamide;N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;Butanamide, N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-;CUR61414,CUR-61414
11 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number7204CR
- Product descriptionN-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
- Packaging5mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5138
- Product descriptionCUR61414
- Packaging10mg
- Price$257
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB20593
- Product descriptionCUR 61414
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB20593
- Product descriptionCUR 61414
- Packaging50mg
- Price$787.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14931
- Product descriptionCUR 61414 ≥98%
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14931
- Product descriptionCUR 61414 ≥98%
- Packaging10mg
- Price$228
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0064795
- Product descriptionCUR61414 >99.0%
- Packaging10mg
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number8605
- Product descriptionCUR61414
- Packaging5mg
- Price$1880
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC835000
- Product descriptionCUR61414
- Packaging5mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number366876
- Product descriptionCUR-61414
- Packaging5mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number007123
- Product descriptionCUR 61414
- Packaging1mg
- Price$333
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 7204CR | N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide | 5mg | $232 | 2021-12-16 | Buy |
ApexBio Technology | C5138 | CUR61414 | 10mg | $257 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB20593 | CUR 61414 | 10mg | $225 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB20593 | CUR 61414 | 50mg | $787.5 | 2021-12-16 | Buy |
Cayman Chemical | 14931 | CUR 61414 ≥98% | 5mg | $120 | 2024-03-01 | Buy |
Cayman Chemical | 14931 | CUR 61414 ≥98% | 10mg | $228 | 2024-03-01 | Buy |
ChemScene | CS-0064795 | CUR61414 >99.0% | 10mg | $690 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 8605 | CUR61414 | 5mg | $1880 | 2021-12-16 | Buy |
TRC | C835000 | CUR61414 | 5mg | $340 | 2021-12-16 | Buy |
Usbiological | 366876 | CUR-61414 | 5mg | $322 | 2021-12-16 | Buy |
Usbiological | 007123 | CUR 61414 | 1mg | $333 | 2021-12-16 | Buy |
Properties
Melting point :35-40°C
Boiling point :714.1±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble2mg/mL (clear solution, warmed)
pka :8.42±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Boiling point :714.1±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble2mg/mL (clear solution, warmed)
pka :8.42±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
CUR 61414 is a potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM). It binds directly with the pathway activator Smoothened (Ki = 44 nM). CUR 61414 blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in mouse skin.Related product price
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