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ChemicalBook >> CAS DataBase List >> CUR 61414

CUR 61414

CUR 61414 price.
  • $120 - $1880
  • Product name: CUR 61414
  • CAS: 334998-36-6
  • MF: C31H42N4O5
  • MW: 550.69
  • EINECS:
  • MDL Number:MFCD20275055
  • Synonyms:CUR 61414;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-benzamide;N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide;Butanamide, N-[(3S,5S)-1-(1,3-benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-;CUR61414,CUR-61414
11 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number7204CR
  • Product descriptionN-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
  • Packaging5mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5138
  • Product descriptionCUR61414
  • Packaging10mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB20593
  • Product descriptionCUR 61414
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB20593
  • Product descriptionCUR 61414
  • Packaging50mg
  • Price$787.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14931
  • Product descriptionCUR 61414 ≥98%
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14931
  • Product descriptionCUR 61414 ≥98%
  • Packaging10mg
  • Price$228
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0064795
  • Product descriptionCUR61414 >99.0%
  • Packaging10mg
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number8605
  • Product descriptionCUR61414
  • Packaging5mg
  • Price$1880
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC835000
  • Product descriptionCUR61414
  • Packaging5mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number366876
  • Product descriptionCUR-61414
  • Packaging5mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number007123
  • Product descriptionCUR 61414
  • Packaging1mg
  • Price$333
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7204CR N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide 5mg $232 2021-12-16 Buy
ApexBio Technology C5138 CUR61414 10mg $257 2021-12-16 Buy
Biosynth Carbosynth FB20593 CUR 61414 10mg $225 2021-12-16 Buy
Biosynth Carbosynth FB20593 CUR 61414 50mg $787.5 2021-12-16 Buy
Cayman Chemical 14931 CUR 61414 ≥98% 5mg $120 2024-03-01 Buy
Cayman Chemical 14931 CUR 61414 ≥98% 10mg $228 2024-03-01 Buy
ChemScene CS-0064795 CUR61414 >99.0% 10mg $690 2021-12-16 Buy
Medical Isotopes, Inc. 8605 CUR61414 5mg $1880 2021-12-16 Buy
TRC C835000 CUR61414 5mg $340 2021-12-16 Buy
Usbiological 366876 CUR-61414 5mg $322 2021-12-16 Buy
Usbiological 007123 CUR 61414 1mg $333 2021-12-16 Buy

Properties

Melting point :35-40°C
Boiling point :714.1±60.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :DMSO: soluble2mg/mL (clear solution, warmed)
pka :8.42±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

CUR 61414 is a potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM). It binds directly with the pathway activator Smoothened (Ki = 44 nM). CUR 61414 blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in mouse skin.

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