Calpain Inhibitor I
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- $31 - $1900
- Product name: Calpain Inhibitor I
- CAS: 110044-82-1
- MF: C20H37N3O4
- MW: 383.53
- EINECS:999-999-2
- MDL Number:MFCD00065505
- Synonyms:AC-LEU-LEU-NLE-H (ALDEHYDE);AC-LEU-LEU-NORLEUCINAL;AC-LL-NORLEUCINAL;ac-llnl-cho;Ac-Leu-Leu-Nle-al;Ac-LLnL-CHO, ALLN, MG-101, N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal;Calpain Inhibitor I,96%;N-Acetyl-L-leucine-L-leucine-L-norleucinal
39 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1MG
- 2mg
- 5mg
- 10mM(in 1mL DMSO)
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2300AH
- Product descriptionCalpain Inhibitor I
- Packaging5mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61766
- Product descriptionCalpain Inhibitor I, 95+%
- Packaging5mg
- Price$91.8
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging5MG
- Price$665.98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging25MG
- Price$750.68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpainInhibitorI,ALLN
- Packaging10mM(in 1mL DMSO)
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpainInhibitorI,ALLN
- Packaging25mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIC0320
- Product descriptionCalpain inhibitor I
- Packaging5mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIC0320
- Product descriptionCalpain inhibitor I
- Packaging25mg
- Price$161
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC29614
- Product descriptionCalpain inhibitor I
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC29614
- Product descriptionCalpain inhibitor I
- Packaging25mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC29614
- Product descriptionCalpain inhibitor I
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC29614
- Product descriptionCalpain inhibitor I
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC29614
- Product descriptionCalpain inhibitor I
- Packaging250mg
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14921
- Product descriptionCalpain Inhibitor I ≥95%
- Packaging1mg
- Price$31
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14921
- Product descriptionCalpain Inhibitor I ≥95%
- Packaging5mg
- Price$61
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2300AH | Calpain Inhibitor I | 5mg | $164 | 2021-12-16 | Buy |
| Alfa Aesar | J61766 | Calpain Inhibitor I, 95+% | 5mg | $91.8 | 2023-06-20 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 5MG | $665.98 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 25MG | $750.68 | 2021-12-16 | Buy |
| ApexBio Technology | A2602 | CalpainInhibitorI,ALLN | 10mM(in 1mL DMSO) | $86 | 2021-12-16 | Buy |
| ApexBio Technology | A2602 | CalpainInhibitorI,ALLN | 25mg | $165 | 2021-12-16 | Buy |
| Apolloscientific | BIC0320 | Calpain inhibitor I | 5mg | $54 | 2021-12-16 | Buy |
| Apolloscientific | BIC0320 | Calpain inhibitor I | 25mg | $161 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC29614 | Calpain inhibitor I | 10mg | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC29614 | Calpain inhibitor I | 25mg | $325 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC29614 | Calpain inhibitor I | 50mg | $450 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC29614 | Calpain inhibitor I | 100mg | $700 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC29614 | Calpain inhibitor I | 250mg | $1400 | 2021-12-16 | Buy |
| Cayman Chemical | 14921 | Calpain Inhibitor I ≥95% | 1mg | $31 | 2024-03-01 | Buy |
| Cayman Chemical | 14921 | Calpain Inhibitor I ≥95% | 5mg | $61 | 2024-03-01 | Buy |
Properties
Melting point :182 °C
Boiling point :510.42°C (rough estimate)
Density :1.1322 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :13.53±0.46(Predicted)
color :white
Water Solubility :Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.
BRN :7656053
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Boiling point :510.42°C (rough estimate)
Density :1.1322 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :13.53±0.46(Predicted)
color :white
Water Solubility :Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.
BRN :7656053
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
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Description
Calpain inhibitor I is a synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). At 10-100 μM calpain inhibitor I dose-dependently prevents the degradation of IκBα and IκBβ by the ubiquitin-proteasome complex, which blocks activation of NFκB and the production of TNF and IL-1β, suggesting a potential therapeutic effect for inflammatory diseases. At 10 μM, calpain inhibitor I can inhibit nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.More related product prices
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