Calpain Inhibitor I
|
- $35 - $1900
- Product name: Calpain Inhibitor I
- CAS: 110044-82-1
- MF: C20H37N3O4
- MW: 383.53
- EINECS:999-999-2
- MDL Number:MFCD00065505
- Synonyms:AC-LEU-LEU-NLE-H (ALDEHYDE);AC-LEU-LEU-NORLEUCINAL;AC-LL-NORLEUCINAL;ac-llnl-cho;Ac-Leu-Leu-Nle-al;Ac-LLnL-CHO, ALLN, MG-101, N-Acetyl-Leu-Leu-Norleu-al, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal;Calpain Inhibitor I,96%;N-Acetyl-L-leucine-L-leucine-L-norleucinal
64 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 1MG
- 5mg
- 10mg
- 2mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in 1mL DMSO)
- 25MG
- 25.00mg
- 50.00mg
- 50mg
- 10mM(in1mLDMSO)
- 100.00mg
- 100MG
- 250MG
- 1g
- ManufacturerACHEMBLOCK
- Product numberY228839
- Product descriptionMG-101 97.00%
- Packaging25MG
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228839
- Product descriptionMG-101 97.00%
- Packaging100MG
- Price$465
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228839
- Product descriptionMG-101 97.00%
- Packaging250MG
- Price$700
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2300AH
- Product descriptionCalpain Inhibitor I
- Packaging5mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging25MG
- Price$750.68
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000008
- Product descriptionCALPAIN INHIBITOR I 95.00%
- Packaging5MG
- Price$665.98
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpain Inhibitor I, ALLN
- Packaging25mg
- Price$182
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpain Inhibitor I, ALLN
- Packaging5mg
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpain Inhibitor I, ALLN
- Packaging10mM(in1mLDMSO)
- Price$66
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2602
- Product descriptionCalpainInhibitorI,ALLN
- Packaging10mM(in 1mL DMSO)
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIC0320
- Product descriptionCalpain inhibitor I
- Packaging5mg
- Price$55
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIC0320
- Product descriptionCalpain inhibitor I
- Packaging25mg
- Price$218
- Updated2026-06-04
- Buy
- ManufacturerArctom
- Product numberHY-18964
- Product descriptionMG-101 98.0%
- Packaging25mg
- Price$181
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18964
- Product descriptionMG-101 98.0%
- Packaging5mg
- Price$57
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-18964
- Product descriptionMG-101 98.0%
- Packaging10mg
- Price$86
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y228839 | MG-101 97.00% | 25MG | $210 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228839 | MG-101 97.00% | 100MG | $465 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228839 | MG-101 97.00% | 250MG | $700 | 2026-05-27 | Buy |
| AK Scientific | 2300AH | Calpain Inhibitor I | 5mg | $164 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 25MG | $750.68 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000008 | CALPAIN INHIBITOR I 95.00% | 5MG | $665.98 | 2021-12-16 | Buy |
| ApexBio Technology | A2602 | Calpain Inhibitor I, ALLN | 25mg | $182 | 2026-05-06 | Buy |
| ApexBio Technology | A2602 | Calpain Inhibitor I, ALLN | 5mg | $61 | 2026-05-06 | Buy |
| ApexBio Technology | A2602 | Calpain Inhibitor I, ALLN | 10mM(in1mLDMSO) | $66 | 2026-05-06 | Buy |
| ApexBio Technology | A2602 | CalpainInhibitorI,ALLN | 10mM(in 1mL DMSO) | $86 | 2021-12-16 | Buy |
| Apolloscientific | BIC0320 | Calpain inhibitor I | 5mg | $55 | 2026-06-04 | Buy |
| Apolloscientific | BIC0320 | Calpain inhibitor I | 25mg | $218 | 2026-06-04 | Buy |
| Arctom | HY-18964 | MG-101 98.0% | 25mg | $181 | 2026-05-26 | Buy |
| Arctom | HY-18964 | MG-101 98.0% | 5mg | $57 | 2026-05-26 | Buy |
| Arctom | HY-18964 | MG-101 98.0% | 10mg | $86 | 2026-05-26 | Buy |
Properties
Melting point :182 °C
Boiling point :510.42°C (rough estimate)
Density :1.1322 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :13.53±0.46(Predicted)
color :white
biological source :synthetic (organic)
Water Solubility :Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.
BRN :7656053
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
InChIKey :FMYKJLXRRQTBOR-BZSNNMDCSA-N
SMILES :[H]C(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
Boiling point :510.42°C (rough estimate)
Density :1.1322 (rough estimate)
refractive index :1.6300 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :13.53±0.46(Predicted)
color :white
biological source :synthetic (organic)
Water Solubility :Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.
BRN :7656053
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
InChIKey :FMYKJLXRRQTBOR-BZSNNMDCSA-N
SMILES :[H]C(=O)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Calpain inhibitor I is a synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). At 10-100 μM calpain inhibitor I dose-dependently prevents the degradation of IκBα and IκBβ by the ubiquitin-proteasome complex, which blocks activation of NFκB and the production of TNF and IL-1β, suggesting a potential therapeutic effect for inflammatory diseases. At 10 μM, calpain inhibitor I can inhibit nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.More related product prices
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
Meryer (Shanghai) Chemical Technology Co., Ltd.
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Thermo Fisher Scientific
Beijing HuaMeiHuLiBiological Chemical
Haoyuan Chemexpress Co., Ltd.