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ChemicalBook >> CAS DataBase List >> Captopril

Captopril

Captopril price.
  • $5 - $3326.4
  • Product name: Captopril
  • CAS: 62571-86-2
  • MF: C9H15NO3S
  • MW: 217.29
  • EINECS:263-607-1
  • MDL Number:MFCD00168073
  • Synonyms:Captopril (200 mg);Captopril Cardiovascular;(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline;3-Mercapto-2-Methylpropanoic acid 1,2-diphenylethylaMine salt (MMPA);CAPTOPRIL(RG);Captopril (Capoten);(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid;Captopril for system suitability
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  • AK Scientific
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  • 1gm:
  • 48Tests
  • 96Tests
  • 250mgs:
  • y0001182
  • c0430000
  • ManufacturerAK Scientific
  • Product numberJ10167
  • Product descriptionCaptopril
  • Packaging25mg
  • Price$19.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH526
  • Product descriptionCaptopril
  • Packaging25g
  • Price$67
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ10167
  • Product descriptionCaptopril
  • Packaging1g
  • Price$69
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ95107
  • Product descriptionCaptopril
  • Packaging100g
  • Price$100
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ63593
  • Product descriptionCaptopril
  • Packaging1g
  • Price$62.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ63593
  • Product descriptionCaptopril
  • Packaging5g
  • Price$147.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ63593
  • Product descriptionCaptopril
  • Packaging25g
  • Price$504.65
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA177871
  • Product description(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177871
  • Product description(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+%
  • Packaging1g
  • Price$15
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177871
  • Product description(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+%
  • Packaging5g
  • Price$32
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA177871
  • Product description(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+%
  • Packaging25g
  • Price$73
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001838
  • Product descriptionCaptopril 95.00%
  • Packaging1G
  • Price$130.2
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001838
  • Product descriptionCaptopril 95.00%
  • Packaging10G
  • Price$1166.55
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001838
  • Product descriptionCaptopril 95.00%
  • Packaging100G
  • Price$3326.4
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4078
  • Product descriptionCaptopril
  • Packaging100mg
  • Price$53
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4078
  • Product descriptionCaptopril
  • Packaging500mg
  • Price$76
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10167 Captopril 25mg $19.8 2021-12-16 Buy
AK Scientific H526 Captopril 25g $67 2021-12-16 Buy
AK Scientific J10167 Captopril 1g $69 2021-12-16 Buy
AK Scientific J95107 Captopril 100g $100 2021-12-16 Buy
Alfa Aesar J63593 Captopril 1g $62.65 2024-03-01 Buy
Alfa Aesar J63593 Captopril 5g $147.65 2024-03-01 Buy
Alfa Aesar J63593 Captopril 25g $504.65 2024-03-01 Buy
Ambeed A177871 (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+% 100mg $5 2021-12-16 Buy
Ambeed A177871 (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+% 1g $15 2021-12-16 Buy
Ambeed A177871 (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+% 5g $32 2021-12-16 Buy
Ambeed A177871 (S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylicacid 99+% 25g $73 2021-12-16 Buy
American Custom Chemicals Corporation API0001838 Captopril 95.00% 1G $130.2 2021-12-16 Buy
American Custom Chemicals Corporation API0001838 Captopril 95.00% 10G $1166.55 2021-12-16 Buy
American Custom Chemicals Corporation API0001838 Captopril 95.00% 100G $3326.4 2021-12-16 Buy
ApexBio Technology A4078 Captopril 100mg $53 2021-12-16 Buy
ApexBio Technology A4078 Captopril 500mg $76 2021-12-16 Buy

Properties

Melting point :104-108 °C (lit.)
Boiling point :427.0±40.0 °C(Predicted)
alpha :-129.5 º (c=1, EtOH)
Density :1.2447 (rough estimate)
refractive index :-127.5 ° (C=1.7, EtOH)
storage temp. :room temp
solubility :H2O: 0.1 g/mL, very slightly hazy, colorless
form :Crystalline Powder
pka :3.7, 9.8(at 25℃)
color :white to off-white
Water Solubility :soluble
Merck :14,1774
BRN :477887
BCS Class :3
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :62571-86-2(CAS DataBase Reference)
NIST Chemistry Reference :Captopril(62571-86-2)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Angiotensin-converting enzyme (ACE) removes the C-terminal dipeptide from angiotensin I to form angiotensin II, a powerful vasoconstrictor. ACE is a key regulator of the renin-angiotensin system and an important drug target for the treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications in diabetes. As the first nonpeptidic ACE inhibitor to be developed (IC50 = 6.3 nM), captopril was discovered based on bradykinin-potentiating peptides isolated from the venom of B. Jararaca, a pit viper native to Brazil. It does not exhibit a domain preference for binding either the C- or N-terminal active sites of the somatic form of ACE, which may account for some of captopril’s negative side effects. Captopril is also a competitive and reversible inhibitor of leukotriene (LTA4) hydrolase, which results in the disruption of LTB4 synthesis at an IC50 value of 14 μM.

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