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ChemicalBook >> CAS DataBase List >> Cepharanthine

Cepharanthine

Cepharanthine price.
  • $5 - $975.45
  • Product name: Cepharanthine
  • CAS: 481-49-2
  • MF: C37H38N2O6
  • MW: 606.71
  • EINECS:228-085-1
  • MDL Number:MFCD00210482
  • Synonyms:1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-;Cepharanthine, >=98%;CEPHARANTHINE;OXYACANTHAN,6',12'-DIMETHOXY-2,2'-DIMETHYL-6,7-(METHYLLENEBIS (OXY))-;o-methylcepharanoline ;6',12'-DIMETHOXY-2,2'-DIMETHYL-6,7-(METHYLENEBIS(OXY)OXYACANTHAN);CEPHARANTHINE95%,98%;CEPHARANTHINE: OXYACANTHAN,6'',12''-DIMETHOXY-2,2''-DIMETHY1-6,7-(METHYLLENEBIS (OXY))-,
37 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500MG
  • 1g
  • 10g
  • ManufacturerAK Scientific
  • Product numberJ54406
  • Product descriptionCepharanthine
  • Packaging100mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA508305
  • Product descriptionCepharanthine 97%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA508305
  • Product descriptionCepharanthine 97%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA508305
  • Product descriptionCepharanthine 97%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA508305
  • Product descriptionCepharanthine 97%
  • Packaging250mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA508305
  • Product descriptionCepharanthine 97%
  • Packaging1g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001933
  • Product descriptionCEPHARANTHINE 95.00%
  • Packaging100MG
  • Price$583.21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001933
  • Product descriptionCEPHARANTHINE 95.00%
  • Packaging500MG
  • Price$681.69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001933
  • Product descriptionCEPHARANTHINE 95.00%
  • Packaging1G
  • Price$975.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2771
  • Product descriptionCepharanthine
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2771
  • Product descriptionCepharanthine
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024273
  • Product descriptionCepharanthine 97%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024273
  • Product descriptionCepharanthine 97%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024273
  • Product descriptionCepharanthine 97%
  • Packaging250mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS024273
  • Product descriptionCepharanthine 97%
  • Packaging1g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1897
  • Product descriptionCepharanthine
  • Packaging10mg
  • Price$29
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J54406 Cepharanthine 100mg $43 2021-12-16 Buy
Ambeed A508305 Cepharanthine 97% 10mg $5 2021-12-16 Buy
Ambeed A508305 Cepharanthine 97% 50mg $8 2021-12-16 Buy
Ambeed A508305 Cepharanthine 97% 100mg $15 2021-12-16 Buy
Ambeed A508305 Cepharanthine 97% 250mg $23 2021-12-16 Buy
Ambeed A508305 Cepharanthine 97% 1g $57 2021-12-16 Buy
American Custom Chemicals Corporation API0001933 CEPHARANTHINE 95.00% 100MG $583.21 2021-12-16 Buy
American Custom Chemicals Corporation API0001933 CEPHARANTHINE 95.00% 500MG $681.69 2021-12-16 Buy
American Custom Chemicals Corporation API0001933 CEPHARANTHINE 95.00% 1G $975.45 2021-12-16 Buy
ApexBio Technology N2771 Cepharanthine 20mg $40 2021-12-16 Buy
ApexBio Technology N2771 Cepharanthine 10mM(in 1mL DMSO) $60 2021-12-16 Buy
Arctom AS024273 Cepharanthine 97% 50mg $8 2021-12-16 Buy
Arctom AS024273 Cepharanthine 97% 100mg $15 2021-12-16 Buy
Arctom AS024273 Cepharanthine 97% 250mg $23 2021-12-16 Buy
Arctom AS024273 Cepharanthine 97% 1g $56 2021-12-16 Buy
AvaChem 1897 Cepharanthine 10mg $29 2021-12-16 Buy

Properties

Melting point :145-155°
alpha :D20 +277° (c = 2 in chloroform)
Boiling point :654.03°C (rough estimate)
Density :1.1761 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO (35 mg/mL) or ethanol (20 mg/mL)
form :solid
pka :7.61±0.20(Predicted)
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES :C1CC2C=C3OCOC3=C3OC4C(OC)=CC5CCN(C)[C@]([H])(CC6=CC(=C(OC)C=C6)OC6C=CC(C[C@@]([H])(C=23)N1C)=CC=6)C=5C=4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes. It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models. Cepharanthine can decrease LPS-stimulated expression of TNF-α, IL-6, and IL-1β in macrophages and prevent the activation of NF-κB, ERK, JNK, and p38 MAPK. It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.

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