Cepharanthine
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- $5 - $1144
- Product name: Cepharanthine
- CAS: 481-49-2
- MF: C37H38N2O6
- MW: 606.71
- EINECS:228-085-1
- MDL Number:MFCD00210482
- Synonyms:1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-;CEPHARANTHINE;OXYACANTHAN,6',12'-DIMETHOXY-2,2'-DIMETHYL-6,7-(METHYLLENEBIS (OXY))-;o-methylcepharanoline ;6',12'-DIMETHOXY-2,2'-DIMETHYL-6,7-(METHYLENEBIS(OXY)OXYACANTHAN);CEPHARANTHINE95%,98%;CEPHARANTHINE: OXYACANTHAN,6'',12''-DIMETHOXY-2,2''-DIMETHY1-6,7-(METHYLLENEBIS (OXY))-,;[methylenebis(oxy)]-
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 5mg
- 10mM*1mLinDMSO(Solution)
- 20mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 500ug
- 2.5mg
- 10mg
- 1mlx10mM(inDMSO)
- 25mg
- 50mg
- 100mg
- 500MG
- 10mM(in1mLDMSO)
- 250mg
- 10mM(in 1mL DMSO)
- 1g
- 10g
- 1 mg
- ManufacturerAK Scientific
- Product numberJ54406
- Product descriptionCepharanthine
- Packaging100mg
- Price$43
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging100mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging50mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging250mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA508305
- Product descriptionCepharanthine 97%
- Packaging1g
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging100MG
- Price$583.21
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging500MG
- Price$681.69
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001933
- Product descriptionCEPHARANTHINE 95.00%
- Packaging1G
- Price$975.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2771
- Product descriptionCepharanthine
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2771
- Product descriptionCepharanthine
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberN2771
- Product descriptionCepharanthine
- Packaging20mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N6972
- Product descriptionCepharanthine 99.87%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$55
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberAS024273
- Product descriptionCepharanthine 97%
- Packaging1g
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-N6972R
- Product descriptionCepharanthine (Standard) 98%
- Packaging5mg
- Price$47
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6972
- Product descriptionCepharanthine 99.87%
- Packaging50mg
- Price$53
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J54406 | Cepharanthine | 100mg | $43 | 2021-12-16 | Buy |
| Ambeed | A508305 | Cepharanthine 97% | 100mg | $15 | 2021-12-16 | Buy |
| Ambeed | A508305 | Cepharanthine 97% | 10mg | $5 | 2021-12-16 | Buy |
| Ambeed | A508305 | Cepharanthine 97% | 50mg | $8 | 2021-12-16 | Buy |
| Ambeed | A508305 | Cepharanthine 97% | 250mg | $23 | 2021-12-16 | Buy |
| Ambeed | A508305 | Cepharanthine 97% | 1g | $57 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 100MG | $583.21 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 500MG | $681.69 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001933 | CEPHARANTHINE 95.00% | 1G | $975.45 | 2021-12-16 | Buy |
| ApexBio Technology | N2771 | Cepharanthine | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | N2771 | Cepharanthine | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | N2771 | Cepharanthine | 20mg | $55 | 2026-05-06 | Buy |
| Arctom | HY-N6972 | Cepharanthine 99.87% | 10mM*1mLinDMSO(Solid+Solvent) | $55 | 2026-05-26 | Buy |
| Arctom | AS024273 | Cepharanthine 97% | 1g | $56 | 2021-12-16 | Buy |
| Arctom | HY-N6972R | Cepharanthine (Standard) 98% | 5mg | $47 | 2026-05-26 | Buy |
| Arctom | HY-N6972 | Cepharanthine 99.87% | 50mg | $53 | 2026-05-26 | Buy |
Properties
Melting point :145-155°
alpha :D20 +277° (c = 2 in chloroform)
Boiling point :654.03°C (rough estimate)
Density :1.1761 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO (35 mg/mL) or ethanol (20 mg/mL)
form :solid
pka :7.61±0.20(Predicted)
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Major Application :metabolomics
vitamins, nutraceuticals, and natural products InChIKey :YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES :C1CC2C=C3OCOC3=C3OC4C(OC)=CC5CCN(C)[C@]([H])(CC6=CC(=C(OC)C=C6)OC6C=CC(C[C@@]([H])(C=23)N1C)=CC=6)C=5C=4
alpha :D20 +277° (c = 2 in chloroform)
Boiling point :654.03°C (rough estimate)
Density :1.1761 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Soluble in DMSO (35 mg/mL) or ethanol (20 mg/mL)
form :solid
pka :7.61±0.20(Predicted)
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Major Application :metabolomics
vitamins, nutraceuticals, and natural products InChIKey :YVPXVXANRNDGTA-WDYNHAJCSA-N
SMILES :C1CC2C=C3OCOC3=C3OC4C(OC)=CC5CCN(C)[C@]([H])(CC6=CC(=C(OC)C=C6)OC6C=CC(C[C@@]([H])(C=23)N1C)=CC=6)C=5C=4
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes. It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models. Cepharanthine can decrease LPS-stimulated expression of TNF-α, IL-6, and IL-1β in macrophages and prevent the activation of NF-κB, ERK, JNK, and p38 MAPK. It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.Related product price
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Dimethyl sulfide
$17-43575.2 -
Dimethyl ether
$75-649 -
Dimethyl carbonate
$5-1610
Suppliers and manufacturers
Shaanxi Xianhe Biotech Co., Ltd
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Hefei Hangang Pharmaceutical Technology Co., Ltd.
Hefei TNJ Chemical Industry Co.,Ltd.
AFINE CHEMICALS LIMITED
Finetech Industry Limited
Cepharanthine
CAS:481-49-2
