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ChemicalBook >> CAS DataBase List >> DDD85646

DDD85646

DDD85646 price.
  • $98 - $1950
  • Product name: DDD85646
  • CAS: 1215010-55-1
  • MF: C21H24Cl2N6O2S
  • MW: 495.43
  • EINECS:
  • MDL Number:
  • Synonyms:DDD85646;DDD 85646 (DDD85646);Benzenesulfonamide, 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-;DDD85646 Hydrochloride;African trypanosomiasis,N-myristoyltransferase,inhibit,DDD85646,Inhibitor,trypanosoma brucei,DNA/RNA Synthesis,NMT,Parasite;2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide;2,6-dichloro-4-[2-(piperazin-1-yl)pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzene-1-sulfonamide;DDD85646, 10 mM in DMSO
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 2.5mg
  • 1mL(10mMinDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98
  • Packaging1mg
  • Price$98
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98%byHPLC
  • Packaging5mg
  • Price$242
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98
  • Packaging10mg
  • Price$357
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98
  • Packaging25mg
  • Price$590
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98
  • Packaging50mg
  • Price$812
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPKK
  • Product description2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98
  • Packaging100mg
  • Price$1108
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203201
  • Product descriptionDDD85646 98.00%
  • Packaging1G
  • Price$1650
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203201
  • Product descriptionDDD85646 98.00%
  • Packaging100MG
  • Price$660
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203201
  • Product descriptionDDD85646 98.00%
  • Packaging25MG
  • Price$220
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2777DF
  • Product description2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide
  • Packaging1mg
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2777DF
  • Product description2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide
  • Packaging5mg
  • Price$553
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2055
  • Product descriptionDDD85646
  • Packaging5mg
  • Price$342
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2055
  • Product descriptionDDD85646
  • Packaging10mg
  • Price$531
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2055
  • Product descriptionDDD85646
  • Packaging1mg
  • Price$108
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA2055
  • Product descriptionDDD85646
  • Packaging1mL(10mMinDMSO)
  • Price$376
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberQYB01055
  • Product descriptionDDD85646
  • Packaging25mg
  • Price$421.75
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98 1mg $98 2026-05-30 Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98%byHPLC 5mg $242 2026-05-30 Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98 10mg $357 2026-05-30 Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98 25mg $590 2026-05-30 Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98 50mg $812 2026-05-30 Buy
aablocks AA01EPKK 2,6-Dichloro-4-(2-(Piperazin-1-Yl)Pyridin-4-Yl)-N-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Benzenesulfonamide 98 100mg $1108 2026-05-30 Buy
ACHEMBLOCK X203201 DDD85646 98.00% 1G $1650 2026-05-27 Buy
ACHEMBLOCK X203201 DDD85646 98.00% 100MG $660 2026-05-27 Buy
ACHEMBLOCK X203201 DDD85646 98.00% 25MG $220 2026-05-27 Buy
AK Scientific 2777DF 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide 1mg $206 2021-12-16 Buy
AK Scientific 2777DF 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide 5mg $553 2021-12-16 Buy
ApexBio Technology BA2055 DDD85646 5mg $342 2026-05-06 Buy
ApexBio Technology BA2055 DDD85646 10mg $531 2026-05-06 Buy
ApexBio Technology BA2055 DDD85646 1mg $108 2026-05-06 Buy
ApexBio Technology BA2055 DDD85646 1mL(10mMinDMSO) $376 2026-05-06 Buy
Biosynth QYB01055 DDD85646 25mg $421.75 2026-06-04 Buy
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Properties

Melting point :>215°C (dec.)
Boiling point :684.3±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
form :Solid
pka :7.04±0.50(Predicted)
color :Off-White to Yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. T. brucei is the parasite responsible for human African trypanosomiasis (HAT), also known as African sleeping sickness, and is transmitted through the tsetse fly. DDD85646 administration in mice (12.5 mg/kg for four days) ameliorated T. brucei in an acute mouse model of HAT. It less potently inhibits growth of T. cruzi (EC50 = 6.9 μM).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
DDD85646
$97.00
DDD85646 CAS:1215010-55-1
Shanghai Lollane Biological Technology Co.,Ltd. Shanghai Beckham Medical Technology Co., Ltd Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Shanghai Chaolan Chemical Technology Center Shanghai Hongye Biotechnology Co. Ltd BOC Sciences Shanghai Dongyang Biotechnology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd.