Dihydromethysticin
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- $31 - $3508
- Product name: Dihydromethysticin
- CAS: 19902-91-1
- MF: C15H16O5
- MW: 276.28
- EINECS:
- MDL Number:MFCD00221731
- Synonyms:6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s) ;6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on ;7,8-dihydromethysticin ;DIHYDROMETHYLSTICIN;7,8-DIHYDROMETHYLSTICIN;5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one;6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one;2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[3,4-(methylenedioxy)phenethyl]-, (S)-
52 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 20mg
- 10mM*1mLinDMSO(Solution)
- 2.5mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 500mg
- 1000mg
- 1mL(10mMinDMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- Manufactureraablocks
- Product numberAA002BTE
- Product description(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98%
- Packaging1mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002BTE
- Product description(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98%
- Packaging5mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002BTE
- Product description(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98%
- Packaging10mg
- Price$98
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002BTE
- Product description(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98%
- Packaging25mg
- Price$186
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002BTE
- Product description(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98%
- Packaging50mg
- Price$316
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106572
- Product descriptionDihydromethysticin 98.00%
- Packaging50MG
- Price$385
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106572
- Product descriptionDihydromethysticin 98.00%
- Packaging100MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX1123
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$363
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000233
- Product description(+)-DIHYDROMETHYSTICIN 95.00%
- Packaging5MG
- Price$933.26
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHBL0000233
- Product description(+)-DIHYDROMETHYSTICIN 95.00%
- Packaging10MG
- Price$1279.46
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA7247
- Product descriptionDihydromethysticin
- Packaging10mg
- Price$378
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA7247
- Product descriptionDihydromethysticin
- Packaging5mg
- Price$225
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA7247
- Product descriptionDihydromethysticin
- Packaging1mL(10mMinDMSO)
- Price$273
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA7247
- Product descriptionDihydromethysticin
- Packaging1mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N0921
- Product descriptionDihydromethysticin 99.94%
- Packaging1mg
- Price$76
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0921
- Product descriptionDihydromethysticin 99.94%
- Packaging10mM*1mLinDMSO(Solution)
- Price$193
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002BTE | (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98% | 1mg | $31 | 2026-05-28 | Buy |
| aablocks | AA002BTE | (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98% | 5mg | $62 | 2026-05-28 | Buy |
| aablocks | AA002BTE | (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98% | 10mg | $98 | 2026-05-28 | Buy |
| aablocks | AA002BTE | (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98% | 25mg | $186 | 2026-05-28 | Buy |
| aablocks | AA002BTE | (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one 98% | 50mg | $316 | 2026-05-28 | Buy |
| ACHEMBLOCK | U106572 | Dihydromethysticin 98.00% | 50MG | $385 | 2026-05-27 | Buy |
| ACHEMBLOCK | U106572 | Dihydromethysticin 98.00% | 100MG | $650 | 2026-05-27 | Buy |
| AK Scientific | X1123 | Dihydromethysticin | 5mg | $363 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000233 | (+)-DIHYDROMETHYSTICIN 95.00% | 5MG | $933.26 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000233 | (+)-DIHYDROMETHYSTICIN 95.00% | 10MG | $1279.46 | 2021-12-16 | Buy |
| ApexBio Technology | BA7247 | Dihydromethysticin | 10mg | $378 | 2026-05-06 | Buy |
| ApexBio Technology | BA7247 | Dihydromethysticin | 5mg | $225 | 2026-05-06 | Buy |
| ApexBio Technology | BA7247 | Dihydromethysticin | 1mL(10mMinDMSO) | $273 | 2026-05-06 | Buy |
| ApexBio Technology | BA7247 | Dihydromethysticin | 1mg | $90 | 2026-05-06 | Buy |
| Arctom | HY-N0921 | Dihydromethysticin 99.94% | 1mg | $76 | 2026-05-26 | Buy |
| Arctom | HY-N0921 | Dihydromethysticin 99.94% | 10mM*1mLinDMSO(Solution) | $193 | 2026-05-26 | Buy |
Properties
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
Major Application :food and beverages
InChI :InChI=1S/C15H16O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h3,5-6,8,11H,2,4,7,9H2,1H3/t11-/m0/s1
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
SMILES :C1(=O)O[C@@H](CCC2=CC=C3OCOC3=C2)CC(OC)=C1
LogP :1.810 (est)
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
Major Application :food and beverages
InChI :InChI=1S/C15H16O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h3,5-6,8,11H,2,4,7,9H2,1H3/t11-/m0/s1
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
SMILES :C1(=O)O[C@@H](CCC2=CC=C3OCOC3=C2)CC(OC)=C1
LogP :1.810 (est)
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.Related product price
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