Dimethylenastron
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- $9 - $900
- Product name: Dimethylenastron
- CAS: 863774-58-7
- MF: C16H18N2O2S
- MW: 302.39
- EINECS:
- MDL Number:MFCD09264157
- Synonyms:Dimethylenastron;2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone;Eg5 Inhibitor III(Dimethylenastron);Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem;Dimethylenastron - Eg5 inhibitor III;Eg5 Inhibitor III;enastron;5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-
31 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Axon Medchem
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 50
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number9354CS
- Product descriptionDimethylenastron
- Packaging25mg
- Price$564
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging1mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging5mg
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging10mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging50mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging100mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging250mg
- Price$87
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA187476
- Product descriptionDimethylenastron 98+%
- Packaging1g
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002504
- Product descriptionDIMETHYLENASTRON 95.00%
- Packaging10MG
- Price$278.25
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2439
- Product descriptionDimethylenastron-Eg5inhibitorIII 98%
- Packaging10mg
- Price$115.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2439
- Product descriptionDimethylenastron-Eg5inhibitorIII 98%
- Packaging50mg
- Price$445.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22357
- Product descriptionDimethylenastron ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22357
- Product descriptionDimethylenastron ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22357
- Product descriptionDimethylenastron ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22357
- Product descriptionDimethylenastron ≥98%
- Packaging25mg
- Price$420
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM255393
- Product description4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one 98%
- Packaging100mg
- Price$628
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9354CS | Dimethylenastron | 25mg | $564 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 1mg | $9 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 5mg | $15 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 10mg | $20 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 50mg | $34 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 100mg | $44 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 250mg | $87 | 2021-12-16 | Buy |
| Ambeed | A187476 | Dimethylenastron 98+% | 1g | $218 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002504 | DIMETHYLENASTRON 95.00% | 10MG | $278.25 | 2021-12-16 | Buy |
| Axon Medchem | Axon2439 | Dimethylenastron-Eg5inhibitorIII 98% | 10mg | $115.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon2439 | Dimethylenastron-Eg5inhibitorIII 98% | 50mg | $445.5 | 2021-12-16 | Buy |
| Cayman Chemical | 22357 | Dimethylenastron ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22357 | Dimethylenastron ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 22357 | Dimethylenastron ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 22357 | Dimethylenastron ≥98% | 25mg | $420 | 2024-03-01 | Buy |
| Chemenu | CM255393 | 4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,7,8-hexahydroquinazolin-5(6H)-one 98% | 100mg | $628 | 2021-12-16 | Buy |
Properties
Boiling point :475.6±55.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.59±0.10(Predicted)
form :powder
color :white to beige
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :9.59±0.10(Predicted)
form :powder
color :white to beige
Safety Information
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Description
Eg5 Inhibitor III, Dimethylenastron is a cell-permeable quinazoline-thione compound that acts as a strong, specific, and reversible inhibitor of the microtubule-stimulated ATPase activity of the mitotic motor, Eg5. Eg5 Inhibitor III, Dimethylenastron shows little effect on the ATPase activity of kinesin-1, -4, -7 and -10. The compound also inhibits bipolar spindle formation in both HeLa cells and in Xenopus egg extracts and induces cell cycle arrest (~1 μM). Eg5 Inhibitor III, Dimethylenastron is shown to induce mitotic arrest, apoptosis and upregulate Hsp70 in human multiple myeloma cells.More related product prices
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