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ChemicalBook >> CAS DataBase List >> Doxorubicin hydrochloride

Doxorubicin hydrochloride

Doxorubicin hydrochloride price.
  • $20 - $2052
  • Product name: Doxorubicin hydrochloride
  • CAS: 25316-40-9
  • MF: C27H29NO11.ClH
  • MW: 579.98
  • EINECS:246-818-3
  • MDL Number:MFCD00077757
  • Synonyms:ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE;DOXORUBICIN HYDROCHLORIDE;HYDROXYDAUNORUBICIN HYDROCHLORIDE
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  • d2975000
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0257-M050
  • Product descriptionDoxorubicin hydrochloride ≥98(HPLC)
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1264
  • Product descriptionAdriblastina 98%
  • Packaging0.1g
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11620
  • Product descriptionDoxorubicinHCl
  • Packaging100mg
  • Price$84
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ64000
  • Product descriptionDoxorubicin hydrochloride
  • Packaging10mg
  • Price$232
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67209
  • Product descriptionDoxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered
  • Packaging1ml
  • Price$475.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ64000
  • Product descriptionDoxorubicin hydrochloride
  • Packaging50mg
  • Price$497
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ67364
  • Product descriptionDoxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered
  • Packaging1ml
  • Price$523
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging50mg
  • Price$20
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging100mg
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging250mg
  • Price$52
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging1g
  • Price$155
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging5g
  • Price$546
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging10g
  • Price$956
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130952
  • Product description(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+%
  • Packaging25g
  • Price$2052
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045717
  • Product descriptionDOXORUBICIN HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$501
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045717
  • Product descriptionDOXORUBICIN HYDROCHLORIDE 95.00%
  • Packaging50MG
  • Price$595
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-D0257-M050 Doxorubicin hydrochloride ≥98(HPLC) 50mg $112 2021-12-16 Buy
AHH API-1264 Adriblastina 98% 0.1g $680 2021-12-16 Buy
AK Scientific J11620 DoxorubicinHCl 100mg $84 2021-12-16 Buy
Alfa Aesar J64000 Doxorubicin hydrochloride 10mg $232 2024-03-01 Buy
Alfa Aesar J67209 Doxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered 1ml $475.65 2024-03-01 Buy
Alfa Aesar J64000 Doxorubicin hydrochloride 50mg $497 2024-03-01 Buy
Alfa Aesar J67364 Doxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered 1ml $523 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 50mg $20 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 100mg $30 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 250mg $52 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 1g $155 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 5g $546 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 10g $956 2021-12-16 Buy
Ambeed A130952 (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 99+% 25g $2052 2021-12-16 Buy
American Custom Chemicals Corporation API0045717 DOXORUBICIN HYDROCHLORIDE 95.00% 5MG $501 2021-12-16 Buy
American Custom Chemicals Corporation API0045717 DOXORUBICIN HYDROCHLORIDE 95.00% 50MG $595 2021-12-16 Buy

Properties

Melting point :216 °C (dec.)(lit.)
alpha :D20 +248±2° (c = 0.1 in methanol)
storage temp. :2-8°C
solubility :Soluble in DMSO at 100 mg/ml; very poorly soluble in ethanol; soluble in water at 10 mg/ml with slight warming.
pka :pKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain)
form :solid
color :orange to dark red
Water Solubility :Soluble in water.
λmax :497nm(H2O)(lit.)
Merck :14,3439
BRN :4229251
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChIKey :MWWSFMDVAYGXBV-RUELKSSGSA-N
CAS DataBase Reference :25316-40-9(CAS DataBase Reference)
EPA Substance Registry System :Doxorubicin hydrochloride (25316-40-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.

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