E6005
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- $16 - $1800
- Product name: E6005
- CAS: 947620-48-6
- MF: C26H24N4O5
- MW: 472.49
- EINECS:
- MDL Number:MFCD28502071
- Synonyms:E6005;RVT-501;E 6005: RVT-501;METHYL 4-((3-(6,7-DIMETHOXY-2-(METHYLAMINO)QUINAZOLIN-4-YL)PHENYL)CARBAMOYL)BENZOATE;RVT-501 E6005;methyl 4-[({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}amino)carbonyl]benzoate;CS-2517;E 6005;E-6005
40 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 10mM*1mLinDMSO
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98%
- Packaging1mg
- Price$16
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96%
- Packaging2mg
- Price$18
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98%
- Packaging5mg
- Price$35
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98%
- Packaging25mg
- Price$86
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98%
- Packaging10mg
- Price$51
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96%
- Packaging50mg
- Price$165
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00IIG2
- Product descriptionMethyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96%
- Packaging100mg
- Price$279
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22506
- Product descriptionE-6005 98%
- Packaging250MG
- Price$400
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22506
- Product descriptionE-6005 98%
- Packaging1G
- Price$1005
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberL22506
- Product descriptionE-6005 98%
- Packaging100MG
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1822DC
- Product descriptionMethyl4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)carbamoyl)benzoate
- Packaging5mg
- Price$203
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberXMB62048
- Product descriptionRVT 501
- Packaging100mg
- Price$1383
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberXMB62048
- Product descriptionRVT 501
- Packaging50mg
- Price$993.5
- Updated2026-06-05
- Buy
- ManufacturerCayman Chemical
- Product number30203
- Product descriptionE6005
- Packaging25mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30203
- Product descriptionE6005 ≥98%
- Packaging25mg
- Price$423
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number30203
- Product descriptionE6005 ≥98%
- Packaging10mg
- Price$190
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98% | 1mg | $16 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96% | 2mg | $18 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98% | 5mg | $35 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98% | 25mg | $86 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate 98% | 10mg | $51 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96% | 50mg | $165 | 2026-05-29 | Buy |
| aablocks | AA00IIG2 | Methyl 4-({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}carbamoyl)benzoate ≥96% | 100mg | $279 | 2026-05-29 | Buy |
| ACHEMBLOCK | L22506 | E-6005 98% | 250MG | $400 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22506 | E-6005 98% | 1G | $1005 | 2026-05-27 | Buy |
| ACHEMBLOCK | L22506 | E-6005 98% | 100MG | $200 | 2026-05-27 | Buy |
| AK Scientific | 1822DC | Methyl4-((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)carbamoyl)benzoate | 5mg | $203 | 2021-12-16 | Buy |
| Biosynth | XMB62048 | RVT 501 | 100mg | $1383 | 2026-06-05 | Buy |
| Biosynth | XMB62048 | RVT 501 | 50mg | $993.5 | 2026-06-05 | Buy |
| Cayman Chemical | 30203 | E6005 | 25mg | $384 | 2024-03-01 | Buy |
| Cayman Chemical | 30203 | E6005 ≥98% | 25mg | $423 | 2026-04-30 | Buy |
| Cayman Chemical | 30203 | E6005 ≥98% | 10mg | $190 | 2026-04-30 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:25.0(Max Conc. mg/mL);52.9(Max Conc. mM)
form :A solid
color :Light yellow to yellow
solubility :DMSO:25.0(Max Conc. mg/mL);52.9(Max Conc. mM)
form :A solid
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
E6005 is an inhibitor of phosphodiesterase 4 (PDE4; IC50 = 2.8 nM). It is selective for PDE4 over PDE1, PDE2, PDE3, and PDE5 with only 46.1, 51.6, 69.4, and 57.4% inhibition, respectively, at 30 μM. It inhibits the production of various cytokines in isolated human lymphocytes and monocytes (IC50s = 0.49-3.1 nM). Topical application of E6005 (0.003-0.3%) reduces ear thickness in a mouse model of oxazolone-induced skin inflammation, as well as reduces oxazolone-induced scratching in mice. It reduces the severity of skin lesions in a model of mite-induced atopic dermatitis. Topical application of E6005 (0.03%) also inhibits the production of leukotriene B4 (LTB4; ) in mouse skin, as well as reduces scratching and cutaneous nerve firing induced by the proteinase-activated receptor 2 (PAR2) agonist SLIGRL-NH2 in mice.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
career henan chemical co
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific
