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ChemicalBook >> CAS DataBase List >> Epothilone A

Epothilone A

Epothilone A price.
  • $49 - $4469.3
  • Product name: Epothilone A
  • CAS: 152044-53-6
  • MF: C26H39NO6S
  • MW: 493.66
  • EINECS:
  • MDL Number:MFCD26960884
  • Synonyms:4,17-Dioxabicyclo14.1.0heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12-tetramethyl-3-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (1S,3S,7S,10R,11S,12S,16R)-;Epothilone-S;(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione;Epothile;4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione,7,11-dihydroxy-8,8,10,12-tetraMethyl-3- [(1E)-1-Methy;Ixabepilone Impurity 5 (Epothilone A);(1S,3S,7S,10R,11S,12S,16R,E)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-(1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione;(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione Epothilone A
Price48 Properties Safety Information Description
48 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 0.1MG
  • 1mg
  • 10mM(in 1mL DMSO)
  • 10μg
  • 100ug
  • 10mM(in1mLDMSO)
  • 1mlx10mM(inDMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1000mg
  • 1g
  • Manufactureraablocks
  • Product numberAA006UH3
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • Packaging10mg
  • Price$77
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006UH3
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • Packaging25mg
  • Price$135
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006UH3
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • Packaging50mg
  • Price$195
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006UH3
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • Packaging5mg
  • Price$55
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA006UH3
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione ≥95%
  • Packaging1mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7523
  • Product descriptionEpothiloneA
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA408460
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98%
  • Packaging50mg
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA408460
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98%
  • Packaging100mg
  • Price$457
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA408460
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98%
  • Packaging10mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA408460
  • Product description(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000872
  • Product descriptionEPOTHILONE A 95.00%
  • Packaging0.1MG
  • Price$742.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000872
  • Product descriptionEPOTHILONE A 95.00%
  • Packaging1MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1623
  • Product descriptionEpothilone A
  • Packaging100mg
  • Price$375
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1623
  • Product descriptionEpothilone A
  • Packaging200mg
  • Price$455
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1623
  • Product descriptionEpothilone A
  • Packaging50mg
  • Price$251
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1623
  • Product descriptionEpothiloneA
  • Packaging10mM(in 1mL DMSO)
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA006UH3 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 10mg $77 2026-05-28 Buy
aablocks AA006UH3 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 25mg $135 2026-05-28 Buy
aablocks AA006UH3 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 50mg $195 2026-05-28 Buy
aablocks AA006UH3 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 5mg $55 2026-05-28 Buy
aablocks AA006UH3 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione ≥95% 1mg $49 2026-05-28 Buy
AK Scientific X7523 EpothiloneA 10mg $336 2021-12-16 Buy
Ambeed A408460 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98% 50mg $306 2021-12-16 Buy
Ambeed A408460 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98% 100mg $457 2021-12-16 Buy
Ambeed A408460 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98% 10mg $155 2021-12-16 Buy
Ambeed A408460 (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione 98% 5mg $120 2021-12-16 Buy
American Custom Chemicals Corporation INB0000872 EPOTHILONE A 95.00% 0.1MG $742.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0000872 EPOTHILONE A 95.00% 1MG $2194.5 2021-12-16 Buy
ApexBio Technology A1623 Epothilone A 100mg $375 2026-05-06 Buy
ApexBio Technology A1623 Epothilone A 200mg $455 2026-05-06 Buy
ApexBio Technology A1623 Epothilone A 50mg $251 2026-05-06 Buy
ApexBio Technology A1623 EpothiloneA 10mM(in 1mL DMSO) $160 2021-12-16 Buy
Next Last

Properties

Melting point :95℃
alpha :D21 -47.1° (c = 1.0 in methanol)
Boiling point :683.3±55.0 °C(Predicted)
Density :1.143
storage temp. :-20°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
pka :13.57±0.70(Predicted)
form :solid
color :White to Off-White
Stability :Stable under recommended storage conditions., Stable Under Recommended Storage C
InChIKey :HESCAJZNRMSMJG-KKQRBIROSA-N
SMILES :[C@]12([H])[C@]([H])(O1)CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O[C@H](/C(/C)=C/C1=CSC(C)=N1)C2

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Epothilone A (Epo A) is a biologically active macrolide produced from the fermentation of the soil bacteria S. cellulosum that was discovered as a potent antimicrotubule agent. In competition assays, epo A binds to β-tubulin with a similar order of magnitude as the binding of paclitaxel to β-tubulin (IC50s = 2.3 and 3.6 μM, respectively). Epo A is cytotoxic to human T-24 bladder carcinoma cells (IC50 = 0.05 μM in vitro) but has poor pharmacological properties and is 2-fold less potent in stabilizing microtubules compared to epothilone B .

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Suppliers and manufacturers

Hubei wei shi reagent group ltd., company Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited Adamas Reagent, Ltd. LGM Pharma Chemsky (shanghai) International Co.,Ltd Jinan Trio PharmaTech Co., Ltd. Hunan Hui Bai Shi Biotechnology Co., Ltd. Dalian Meilun Biotech Co., Ltd.