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ChemicalBook >> CAS DataBase List >> Exemestane

Exemestane

Exemestane price.
  • $75 - $450
  • Product name: Exemestane
  • CAS: 107868-30-4
  • MF: C20H24O2
  • MW: 296.4
  • EINECS:643-090-2
  • MDL Number:MFCD00866994
  • Synonyms:6-methylenandrosta-1,4-diene-3,17-dione;6-METHYLENEANDROSTA-1,4-DIENE-3,17-DIONE;10,13-dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;EXEMESTANE;FCE-24304;AROMASIN;(8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;Exemestan
10 prices
Selected condition:

Brand

  • Cayman Chemical
  • Sigma-Aldrich

Package

  • y0001747
  • 5mg
  • 10mg
  • y0001756
  • 25mg
  • 50mg
  • 150mg
  • 1g
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging10mg
  • Price$105
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging5mg
  • Price$75
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging25mg
  • Price$244
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15008
  • Product descriptionExemestane ≥95%
  • Packaging50mg
  • Price$450
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1269050
  • Product descriptionExemestane United States Pharmacopeia (USP) Reference Standard
  • Packaging150mg
  • Price$352.8
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0006
  • Product descriptionExemestane ≥98% (HPLC)
  • Packaging25mg
  • Price$423
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR1634
  • Product descriptionExemestane Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1g
  • Price$81.9
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0006
  • Product descriptionExemestane ≥98% (HPLC)
  • Packaging5mg
  • Price$105
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0001747
  • Product descriptionExemestane European Pharmacopoeia (EP) Reference Standard
  • Packagingy0001747
  • Price$179
  • Updated2018-11-23
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0001756
  • Product descriptionExemestane for system suitability European Pharmacopoeia (EP) Reference Standard
  • Packagingy0001756
  • Price$179
  • Updated2018-11-23
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 15008 Exemestane ≥95% 10mg $105 2018-11-13 Buy
Cayman Chemical 15008 Exemestane ≥95% 5mg $75 2018-11-13 Buy
Cayman Chemical 15008 Exemestane ≥95% 25mg $244 2018-11-13 Buy
Cayman Chemical 15008 Exemestane ≥95% 50mg $450 2018-11-13 Buy
Sigma-Aldrich 1269050 Exemestane United States Pharmacopeia (USP) Reference Standard 150mg $352.8 2018-11-20 Buy
Sigma-Aldrich PZ0006 Exemestane ≥98% (HPLC) 25mg $423 2018-11-20 Buy
Sigma-Aldrich PHR1634 Exemestane Pharmaceutical Secondary Standard; Certified Reference Material 1g $81.9 2018-11-20 Buy
Sigma-Aldrich PZ0006 Exemestane ≥98% (HPLC) 5mg $105 2018-11-20 Buy
Sigma-Aldrich Y0001747 Exemestane European Pharmacopoeia (EP) Reference Standard y0001747 $179 2018-11-23 Buy
Sigma-Aldrich Y0001756 Exemestane for system suitability European Pharmacopoeia (EP) Reference Standard y0001756 $179 2018-11-23 Buy

Properties

Melting point: :155.13°C
storage temp.  :Store at -20°C
solubility  :DMSO: ≥20mg/mL
form  :powder
color  :white to off-white
optical activity :[α]/D +250 to +300°, c = 1 in methanol
InChIKey :BFYIZQONLCFLEV-DAELLWKTSA-N
CAS DataBase Reference :107868-30-4(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Exemestane is a third generation, irreversible steroidal aromatase inhibitor (Ki = 10.2 nM; Kinact = 26 nM) that induces aromatase degradation leading to a decrease in estrogen levels in plasma. As an androgen analog, exemestane exhibits androgenic effects and has been shown to decrease total and HDL cholesterol, apo A1, and total triglyceride levels. Marketed under the trade name Aromasin?, exemestane has been used to treat estrogen receptor-positive breast cancers in post-menopausal women.

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