Exemestane manufacturers and suppliers

Exemestane suppliers

Properties

Melting point:: 155.13°C

Boiling point:: 453.7±45.0 °C(Predicted)

Density: 1.13±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: DMSO: ≥20mg/mL

form: powder

color: white to off-white

optical activity: [α]/D +250 to +300°, c = 1 in methanol

InChI: InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChIKey: BFYIZQONLCFLEV-DAELLWKTSA-N

SMILES: C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2=C

CAS DataBase Reference: 107868-30-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS08,GHS09

Signal word: Danger

Hazard statements: H360-H411

Precautionary statements: P201-P202-P273-P280-P308+P313-P391

Hazard Codes: T,N

Risk Statements: 60-61-51

Safety Statements: 53-22-36/37-57

WGK Germany: 3

HS Code: 29372900

Hazardous Substances Data: 107868-30-4(Hazardous Substances Data)

Use

For patients resistant to tamoxifen, 25mg of Exemestane, qd, can achieve an objective efficacy rate of 15-28% and a median continuation period of 69-76 weeks. Exemestane is superior to Megestrol, and it can extend the disease progression time. For patients who have worsened conditions following Megestrol treatment, Exemestane can still achieve an objective efficacy rate of 11-13%. A daily 25mg dose of Exemestane has an objective efficacy rate of 6.6% on patients who have not responded to non-steroidal aromatase inhibitors, and the two drugs are not cross-resistant.

You can find Exemestane suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.