Fatostatin A
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- $41 - $1207
- Product name: Fatostatin A
- CAS: 298197-04-3
- MF: C18H19BrN2S
- MW: 375.33
- EINECS:
- MDL Number:MFCD00760867
- Synonyms:Fatostatin A;4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine MonohydrobroMide;Fatostatin A HydrobroMide;2-(2-propylpyridin-4-yl)-4-p-tolylthiazole hydrobromide;25B11 hydrobromide;4-[4-(4-methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide;Fatostatin hydrobromide;Fatostatin
79 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 25.00mg
- 10mM*1mLinDMSO
- 10
- 50.00mg
- 100.00mg
- 200mg
- 250mg
- 50
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1g
- 100mg
- 10mM(1mLinDMSO)
- ManufacturerAK Scientific
- Product number3250CJ
- Product description2-(2-Propylpyridin-4-yl)-4-(p-tolyl)thiazolehydrobromide
- Packaging100mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging100mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging5mg
- Price$41
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging10mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging25mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging50mg
- Price$101
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124858
- Product descriptionFatostatin hydrobromide 98+%
- Packaging1g
- Price$1148
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009805
- Product descriptionFATOSTATIN A HYDROBROMIDE 95.00%
- Packaging5MG
- Price$502.54
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5599
- Product descriptionFatostatinA
- Packaging10mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5599
- Product descriptionFatostatin A
- Packaging10mg
- Price$63
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5599
- Product descriptionFatostatin A
- Packaging50mg
- Price$196
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberSLK-S8284
- Product descriptionFatostatin (125B11) HBr 99.71%
- Packaging10mg
- Price$140
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14452A
- Product descriptionFatostatinhydrobromide 99.52%
- Packaging25mg
- Price$152
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8284
- Product descriptionFatostatin (125B11) HBr 99.71%
- Packaging10mM(1mLinDMSO)
- Price$188
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14452A
- Product descriptionFatostatinhydrobromide 99.52%
- Packaging50mg
- Price$257
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberSLK-S8284
- Product descriptionFatostatin (125B11) HBr 99.71%
- Packaging50mg
- Price$352
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3250CJ | 2-(2-Propylpyridin-4-yl)-4-(p-tolyl)thiazolehydrobromide | 100mg | $242 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 100mg | $135 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 5mg | $41 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 10mg | $56 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 25mg | $78 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 50mg | $101 | 2021-12-16 | Buy |
| Ambeed | A124858 | Fatostatin hydrobromide 98+% | 1g | $1148 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009805 | FATOSTATIN A HYDROBROMIDE 95.00% | 5MG | $502.54 | 2021-12-16 | Buy |
| ApexBio Technology | B5599 | FatostatinA | 10mg | $63 | 2021-12-16 | Buy |
| ApexBio Technology | B5599 | Fatostatin A | 10mg | $63 | 2026-05-06 | Buy |
| ApexBio Technology | B5599 | Fatostatin A | 50mg | $196 | 2026-05-06 | Buy |
| Arctom | SLK-S8284 | Fatostatin (125B11) HBr 99.71% | 10mg | $140 | 2026-05-26 | Buy |
| Arctom | HY-14452A | Fatostatinhydrobromide 99.52% | 25mg | $152 | 2026-05-26 | Buy |
| Arctom | SLK-S8284 | Fatostatin (125B11) HBr 99.71% | 10mM(1mLinDMSO) | $188 | 2026-05-26 | Buy |
| Arctom | HY-14452A | Fatostatinhydrobromide 99.52% | 50mg | $257 | 2026-05-26 | Buy |
| Arctom | SLK-S8284 | Fatostatin (125B11) HBr 99.71% | 50mg | $352 | 2026-05-26 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
color :light yellow to yellow
InChI :1S/C18H18N2S.BrH/c1-3-4-16-11-15(9-10-19-16)18-20-17(12-21-18)14-7-5-13(2)6-8-14;/h5-12H,3-4H2,1-2H3;1H
InChIKey :RJCFNQZVFUMORB-UHFFFAOYSA-N
SMILES :[s]1c(nc(c1)c3ccc(cc3)C)c2cc(ncc2)CCC.Br
solubility :DMSO: ≥10mg/mL
form :powder
color :light yellow to yellow
InChI :1S/C18H18N2S.BrH/c1-3-4-16-11-15(9-10-19-16)18-20-17(12-21-18)14-7-5-13(2)6-8-14;/h5-12H,3-4H2,1-2H3;1H
InChIKey :RJCFNQZVFUMORB-UHFFFAOYSA-N
SMILES :[s]1c(nc(c1)c3ccc(cc3)C)c2cc(ncc2)CCC.Br
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Sterol regulatory element binding proteins (SREBPs) are transcription factors that have pivotal roles in lipogenesis and fat metabolism. The activation of SREBPs requires escort to the Golgi by SREBP cleavage-activating protein (SCAP) followed by proteolytic release of SREBP from the Golgi. Fatostatin is an inhibitor of SREBP activation, preventing SCAP-mediated escort of either SREBP-1 or SREBP-2 to the Golgi (IC50 = 5.6 μM). This blocks constitutive SREBP-mediated gene expression in the human prostate cancer cell line DU145. Fatostatin prevents insulin-induced adipogenesis of 3T3-L1 cells as well as growth induced by insulin-like growth factor 1 in DU145 cells (IC50 = 0.1 μM). Through its actions on SCAP/SREBP-1, it inhibits high glucose-induced upregulation of TGF-β in primary rat mesangial cells. This compound also alters lipid metabolism in vivo, reducing hepatic fat accumulation in ob/ob mice.Related product price
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