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ChemicalBook >> CAS DataBase List >> Febrifugine

Febrifugine

Febrifugine price.
  • $37 - $3854.55
  • Product name: Febrifugine
  • CAS: 24159-07-7
  • MF: C16H19N3O3
  • MW: 301.34
  • EINECS:
  • MDL Number:
  • Synonyms:Febrifugine;β-dichroine;3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one;Febrifugine,Isofebrifugine;3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone;BETA-Febrifugine;febrifugin;4(3H)-Quinazolinone, 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Usbiological
Package
  • 1mg
  • 5MG
  • 10mg
  • 20mg
  • 100mg
  • 250mg
  • 1G
  • ManufacturerAK Scientific
  • Product number1749AB
  • Product description3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0003303
  • Product description3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE 95.00%
  • Packaging5MG
  • Price$500.92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0003303
  • Product description3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE 95.00%
  • Packaging1G
  • Price$3854.55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN92302
  • Product descriptionFebrifugine
  • Packaging20mg
  • Price$488
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS006892
  • Product descriptionFebrifugine
  • Packaging100mg
  • Price$846
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS006892
  • Product descriptionFebrifugine
  • Packaging250mg
  • Price$1268
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1782
  • Product descriptionFebrifugine
  • Packaging5mg
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb104700
  • Product descriptionFebrifugine >98%,Standard References Grade
  • Packaging10mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14246
  • Product descriptionFebrifugine
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14246
  • Product descriptionFebrifugine
  • Packaging5mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0022587
  • Product descriptionFebrifugine
  • Packaging5mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0022587
  • Product descriptionFebrifugine
  • Packaging10mg
  • Price$571
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDCC-078
  • Product descriptionFebrifugine >98%,StandardReferencesGrade
  • Packaging10mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number300268
  • Product descriptionFebrifugine
  • Packaging20mg
  • Price$665
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1749AB 3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one 1mg $139 2021-12-16 Buy
American Custom Chemicals Corporation CCH0003303 3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE 95.00% 5MG $500.92 2021-12-16 Buy
American Custom Chemicals Corporation CCH0003303 3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE 95.00% 1G $3854.55 2021-12-16 Buy
Arctom CFN92302 Febrifugine 20mg $488 2021-12-16 Buy
Arctom AS006892 Febrifugine 100mg $846 2021-12-16 Buy
Arctom AS006892 Febrifugine 250mg $1268 2021-12-16 Buy
AvaChem 1782 Febrifugine 5mg $690 2021-12-16 Buy
Biorbyt Ltd orb104700 Febrifugine >98%,Standard References Grade 10mg $615.4 2021-12-16 Buy
Cayman Chemical 14246 Febrifugine 1mg $37 2024-03-01 Buy
Cayman Chemical 14246 Febrifugine 5mg $169 2024-03-01 Buy
ChemScene CS-0022587 Febrifugine 5mg $336 2021-12-16 Buy
ChemScene CS-0022587 Febrifugine 10mg $571 2021-12-16 Buy
DC Chemicals DCC-078 Febrifugine >98%,StandardReferencesGrade 10mg $400 2021-12-16 Buy
Usbiological 300268 Febrifugine 20mg $665 2021-12-16 Buy

Properties

Melting point :139-140°; mp 154-156°
alpha :D25 +6° (c = 0.5 in chloroform); D25 +28° (c = 0.5 in ethanol)
Density :1.39
storage temp. :2-8°C
solubility :DMF: 1.5 mg/ml; DMSO: 3.0 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 2.5 mg/ml
form :A crystalline solid
Boiling point :508.2±60.0 °C(Predicted)
pka :14.61±0.40(Predicted)
color :White to off-white
InChI :InChI=1S/C16H19N3O3/c20-11(8-14-15(21)6-3-7-17-14)9-19-10-18-13-5-2-1-4-12(13)16(19)22/h1-2,4-5,10,14-15,17,21H,3,6-9H2/t14-,15+/m1/s1
InChIKey :FWVHWDSCPKXMDB-CABCVRRESA-N
SMILES :N1C2=C(C=CC=C2)C(=O)N(CC(=O)C[C@@H]2[C@@H](O)CCCN2)C=1
CAS DataBase Reference :24159-07-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Febrifugine is a quinazolinone alkaloid originally isolated from D. febrifuga that has antimalarial activity. It reduces parasitemia and decreases mortality in mice infected with the P. berghei strain NK65 when administered at a dose of 1 mg/kg per day beginning prior to or on the day of infection.

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