ChemicalBook >> CAS DataBase List >>Febrifugine
Febrifugine
- CAS No.
- 24159-07-7
- Chemical Name:
- Febrifugine
- Synonyms
- febrifugin;ferifugine;β-dichroine;Febrifugine;Radix Dichroae;(+)-Febrifugine;BETA-Febrifugine;Febrifugine USP/EP/BP;Febrifugine,Isofebrifugine;Febrifugine (6-Desoxyswietenine)
- CBNumber:
- CB11178705
- Molecular Formula:
- C16H19N3O3
- Molecular Weight:
- 301.34
- MDL Number:
- MOL File:
- 24159-07-7.mol
Last updated:2024-07-02 08:54:59
Melting point | 139-140°; mp 154-156° |
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alpha | D25 +6° (c = 0.5 in chloroform); D25 +28° (c = 0.5 in ethanol) |
Density | 1.39 |
storage temp. | 2-8°C |
solubility | DMF: 1.5 mg/ml; DMSO: 3.0 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 2.5 mg/ml |
form | A crystalline solid |
Boiling point | 508.2±60.0 °C(Predicted) |
pka | 14.61±0.40(Predicted) |
color | White to off-white |
CAS DataBase Reference | 24159-07-7 |
FDA UNII | 89UWD0FH2I |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
Toxicity | LD50 orally in white mice: 2.5-3.0 mg/kg (Koepfli, 1949) | |||||||||
NFPA 704 |
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Febrifugine price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 14246 | Febrifugine | 24159-07-7 | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 14246 | Febrifugine | 24159-07-7 | 5mg | $169 | 2024-03-01 | Buy |
Usbiological | 300268 | Febrifugine | 24159-07-7 | 20mg | $665 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CCH0003303 | 3-[3-[3(S)-HYDROXYPIPERIDIN-2(R)-YL]-2-OXOPROPYL]-3,4-DIHYDROQUINAZOLIN-4-ONE 95.00% | 24159-07-7 | 1G | $3854.55 | 2021-12-16 | Buy |
ChemScene | CS-0022587 | Febrifugine | 24159-07-7 | 5mg | $336 | 2021-12-16 | Buy |
Febrifugine Chemical Properties,Uses,Production
Description
Febrifugine is a quinazolinone alkaloid originally isolated from D. febrifuga that has antimalarial activity. It reduces parasitemia and decreases mortality in mice infected with the P. berghei strain NK65 when administered at a dose of 1 mg/kg per day beginning prior to or on the day of infection.
Uses
Febrifugine is a quinazoline alkaloid with significant antimalarial and anticancerous efficacy. Febrifugine is an NRF2 inhibitor, that works with halofuginone for the treatment of chemo- and radio-resistant forms of cancer. Febrifugine analogs also functions as antimalarial, anticancer agents and in the prevention of chicken coccidiosis.
Febrifugine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 119)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29823 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24099 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9640 | 58 |
View Lastest Price from Febrifugine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-10 | Febrifugine
24159-07-7
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
- Febrifugine
24159-07-7
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
24159-07-7(Febrifugine)Related Search:
Febrifugine
β-dichroine
3-(3-(3-Hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one
Febrifugine,Isofebrifugine
3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone
BETA-Febrifugine
febrifugin
4(3H)-Quinazolinone, 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-
Radix Dichroae
Febrifugine (6-Desoxyswietenine)
Febrifugine USP/EP/BP
ferifugine
(+)-Febrifugine
24159-07-7