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ChemicalBook >> CAS DataBase List >> G-749

G-749

G-749 price.
  • $50 - $1800
  • Product name: G-749
  • CAS: 1457983-28-6
  • MF: C25H25BrN6O2
  • MW: 521.41
  • EINECS:
  • MDL Number:MFCD28167815
  • Synonyms:G-49;G-749 (Free base);G-749;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one G749;G-749, >=98%;8-bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one; Pyrido[4,3-d]pyrimidin-5(6H)-one, 8-bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]-
19 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging25mg
  • Price$829
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging10mg
  • Price$488
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging5mg
  • Price$326
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging1mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8889
  • Product descriptionG-749
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22139
  • Product descriptionG-749 ≥98%
  • Packaging1mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22139
  • Product descriptionG-749 ≥98%
  • Packaging5mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22139
  • Product descriptionG-749 ≥98%
  • Packaging10mg
  • Price$351
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22139
  • Product descriptionG-749 ≥98%
  • Packaging25mg
  • Price$656
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3343
  • Product descriptionG-749 98.43%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3343
  • Product descriptionG-749 98.43%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3343
  • Product descriptionG-749 98.43%
  • Packaging10mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3343
  • Product descriptionG-749 98.43%
  • Packaging25mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3343
  • Product descriptionG-749 98.43%
  • Packaging50mg
  • Price$638
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003419
  • Product descriptionG-749 98+%
  • Packaging5mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7792
  • Product descriptionG-749 >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 25mg $829 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 10mg $488 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 5mg $326 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 1mg $164 2021-12-16 Buy
ApexBio Technology A8889 G-749 5mg $140 2021-12-16 Buy
Cayman Chemical 22139 G-749 ≥98% 1mg $61 2024-03-01 Buy
Cayman Chemical 22139 G-749 ≥98% 5mg $207 2024-03-01 Buy
Cayman Chemical 22139 G-749 ≥98% 10mg $351 2024-03-01 Buy
Cayman Chemical 22139 G-749 ≥98% 25mg $656 2024-03-01 Buy
ChemScene CS-3343 G-749 98.43% 1mg $50 2021-12-16 Buy
ChemScene CS-3343 G-749 98.43% 5mg $95 2021-12-16 Buy
ChemScene CS-3343 G-749 98.43% 10mg $165 2021-12-16 Buy
ChemScene CS-3343 G-749 98.43% 25mg $375 2021-12-16 Buy
ChemScene CS-3343 G-749 98.43% 50mg $638 2021-12-16 Buy
Crysdot CD31003419 G-749 98+% 5mg $196 2021-12-16 Buy
DC Chemicals DC7792 G-749 >98% 100mg $500 2021-12-16 Buy

Properties

Density :1.487±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :8.32±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.

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