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ChemicalBook >> CAS DataBase List >> G-749

G-749

$50 - $1800
Product name: G-749
CAS: 1457983-28-6
MF: C25H25BrN6O2
MW: 521.41
EINECS:
MDL Number:MFCD28167815
Synonyms:G-49;G-749 (Free base);G-749;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one G749;G-749, >=98%;8-bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one; Pyrido[4,3-d]pyrimidin-5(6H)-one, 8-bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]-

Price19 Properties Safety Information Description

19 prices

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AK Scientific
ApexBio Technology
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

Package

1mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAK Scientific
Product number2183AH
Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging1mg
Price$164
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2183AH
Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging5mg
Price$326
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2183AH
Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging10mg
Price$488
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2183AH
Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging25mg
Price$829
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA8889
Product descriptionG-749
Packaging5mg
Price$140
Updated2021-12-16
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ManufacturerCayman Chemical
Product number22139
Product descriptionG-749 ≥98%
Packaging1mg
Price$61
Updated2024-03-01
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ManufacturerCayman Chemical
Product number22139
Product descriptionG-749 ≥98%
Packaging5mg
Price$207
Updated2024-03-01
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ManufacturerCayman Chemical
Product number22139
Product descriptionG-749 ≥98%
Packaging10mg
Price$351
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number22139
Product descriptionG-749 ≥98%
Packaging25mg
Price$656
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-3343
Product descriptionG-749 98.43%
Packaging1mg
Price$50
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-3343
Product descriptionG-749 98.43%
Packaging5mg
Price$95
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-3343
Product descriptionG-749 98.43%
Packaging10mg
Price$165
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-3343
Product descriptionG-749 98.43%
Packaging25mg
Price$375
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-3343
Product descriptionG-749 98.43%
Packaging50mg
Price$638
Updated2021-12-16
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ManufacturerCrysdot
Product numberCD31003419
Product descriptionG-749 98+%
Packaging5mg
Price$196
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7792
Product descriptionG-749 >98%
Packaging100mg
Price$500
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	2183AH	8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one	1mg	$164	2021-12-16	Buy
AK Scientific	2183AH	8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one	5mg	$326	2021-12-16	Buy
AK Scientific	2183AH	8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one	10mg	$488	2021-12-16	Buy
AK Scientific	2183AH	8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one	25mg	$829	2021-12-16	Buy
ApexBio Technology	A8889	G-749	5mg	$140	2021-12-16	Buy
Cayman Chemical	22139	G-749 ≥98%	1mg	$61	2024-03-01	Buy
Cayman Chemical	22139	G-749 ≥98%	5mg	$207	2024-03-01	Buy
Cayman Chemical	22139	G-749 ≥98%	10mg	$351	2024-03-01	Buy
Cayman Chemical	22139	G-749 ≥98%	25mg	$656	2024-03-01	Buy
ChemScene	CS-3343	G-749 98.43%	1mg	$50	2021-12-16	Buy
ChemScene	CS-3343	G-749 98.43%	5mg	$95	2021-12-16	Buy
ChemScene	CS-3343	G-749 98.43%	10mg	$165	2021-12-16	Buy
ChemScene	CS-3343	G-749 98.43%	25mg	$375	2021-12-16	Buy
ChemScene	CS-3343	G-749 98.43%	50mg	$638	2021-12-16	Buy
Crysdot	CD31003419	G-749 98+%	5mg	$196	2021-12-16	Buy
DC Chemicals	DC7792	G-749 >98%	100mg	$500	2021-12-16	Buy

Next Last

Properties

Density :1.487±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :8.32±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.

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G-749

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