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ChemicalBook >> CAS DataBase List >> G-749

G-749

G-749 price.
  • $34 - $1800
  • Product name: G-749
  • CAS: 1457983-28-6
  • MF: C25H25BrN6O2
  • MW: 521.41
  • EINECS:
  • MDL Number:MFCD28167815
  • Synonyms:G-49;G-749 (Free base);G-749;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one;8-Bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]pyrido[4,3-d]pyrimidin-5(6H)-one G749;G-749, >=98%;8-bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one; Pyrido[4,3-d]pyrimidin-5(6H)-one, 8-bromo-2-[(1-methyl-4-piperidinyl)amino]-4-[(4-phenoxyphenyl)amino]-
Price44 Properties Safety Information Description
44 prices
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Brand
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 25MG
  • 50mg
  • 100MG
  • 250mg
  • 1G
  • ManufacturerACHEMBLOCK
  • Product numberM15645
  • Product descriptionG-749 98%
  • Packaging25MG
  • Price$55
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15645
  • Product descriptionG-749 98%
  • Packaging100MG
  • Price$160
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15645
  • Product descriptionG-749 98%
  • Packaging1G
  • Price$950
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging25mg
  • Price$829
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging1mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging5mg
  • Price$326
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2183AH
  • Product description8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  • Packaging10mg
  • Price$488
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8889
  • Product descriptionG-749
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8889
  • Product descriptionG-749
  • Packaging10mM(in1mLDMSO)
  • Price$88
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8889
  • Product descriptionG-749
  • Packaging5mg
  • Price$122
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8889
  • Product descriptionG-749
  • Packaging1mg
  • Price$50
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-12333
  • Product descriptionDenfivontinib 98.0%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$70
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-12333
  • Product descriptionDenfivontinib 98.0%
  • Packaging5mg
  • Price$61
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12333
  • Product descriptionDenfivontinib 98.0%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$66
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12333
  • Product descriptionDenfivontinib 98.0%
  • Packaging1mg
  • Price$34
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12333
  • Product descriptionDenfivontinib 98.0%
  • Packaging10mg
  • Price$100
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK M15645 G-749 98% 25MG $55 2026-05-27 Buy
ACHEMBLOCK M15645 G-749 98% 100MG $160 2026-05-27 Buy
ACHEMBLOCK M15645 G-749 98% 1G $950 2026-05-27 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 25mg $829 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 1mg $164 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 5mg $326 2021-12-16 Buy
AK Scientific 2183AH 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one 10mg $488 2021-12-16 Buy
ApexBio Technology A8889 G-749 5mg $140 2021-12-16 Buy
ApexBio Technology A8889 G-749 10mM(in1mLDMSO) $88 2026-05-06 Buy
ApexBio Technology A8889 G-749 5mg $122 2026-05-06 Buy
ApexBio Technology A8889 G-749 1mg $50 2026-05-06 Buy
Arctom HY-12333 Denfivontinib 98.0% 10mM*1mLinDMSO(Solution) $70 2026-05-26 Buy
Arctom HY-12333 Denfivontinib 98.0% 5mg $61 2026-05-26 Buy
Arctom HY-12333 Denfivontinib 98.0% 10mM*1mLinDMSO(Solid+Solvent) $66 2026-05-26 Buy
Arctom HY-12333 Denfivontinib 98.0% 1mg $34 2026-05-26 Buy
Arctom HY-12333 Denfivontinib 98.0% 10mg $100 2026-05-26 Buy
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Properties

Density :1.487±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.05 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :8.32±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing lower potency against other tyrosine kinases.

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