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ChemicalBook >> CAS DataBase List >> GANAXOLONE

GANAXOLONE

GANAXOLONE price.
  • $32 - $1138.78
  • Product name: GANAXOLONE
  • CAS: 38398-32-2
  • MF: C22H36O2
  • MW: 332.52
  • EINECS:
  • MDL Number:MFCD09971088
  • Synonyms:3α-hydroxy-3β-methyl-5α-pregnan-20-one;(3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one;1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone;(3α,5α)-3-Hydroxy-3-methylpregnan-20-one;1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone;Pregnan-20-one, 3-hydroxy-3-methyl-, (3α,5α)-;Fampridine Impurity 80;5α-PREGNAN-3β-METHYL-3α-OL-20-ONE
15 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5MG
  • 10MG
  • 25mg
  • 50MG
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008418
  • Product descriptionGANAXOLONE 95.00%
  • Packaging5MG
  • Price$502
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008418
  • Product descriptionGANAXOLONE 95.00%
  • Packaging10MG
  • Price$685.21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008418
  • Product descriptionGANAXOLONE 95.00%
  • Packaging50MG
  • Price$1138.78
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7092
  • Product descriptionGanaxolone
  • Packaging10mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7092
  • Product descriptionGanaxolone
  • Packaging50mg
  • Price$975
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20919
  • Product descriptionGanaxolone ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20919
  • Product descriptionGanaxolone ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20919
  • Product descriptionGanaxolone ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20919
  • Product descriptionGanaxolone ≥98%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD13014187
  • Product description1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone 97%
  • Packaging1g
  • Price$738
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD13014187
  • Product description1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone 97%
  • Packaging250mg
  • Price$297
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number70380
  • Product descriptionGanaxolone
  • Packaging250mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG7795
  • Product descriptionGanaxolone solid
  • Packaging25mg
  • Price$677
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG7795
  • Product descriptionGanaxolone solid
  • Packaging5mg
  • Price$196
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberG235005
  • Product descriptionGanaxolone
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008418 GANAXOLONE 95.00% 5MG $502 2021-12-16 Buy
American Custom Chemicals Corporation API0008418 GANAXOLONE 95.00% 10MG $685.21 2021-12-16 Buy
American Custom Chemicals Corporation API0008418 GANAXOLONE 95.00% 50MG $1138.78 2021-12-16 Buy
ApexBio Technology B7092 Ganaxolone 10mg $234 2021-12-16 Buy
ApexBio Technology B7092 Ganaxolone 50mg $975 2021-12-16 Buy
Cayman Chemical 20919 Ganaxolone ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 20919 Ganaxolone ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 20919 Ganaxolone ≥98% 10mg $153 2024-03-01 Buy
Cayman Chemical 20919 Ganaxolone ≥98% 25mg $343 2024-03-01 Buy
Crysdot CD13014187 1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone 97% 1g $738 2021-12-16 Buy
Crysdot CD13014187 1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone 97% 250mg $297 2021-12-16 Buy
Medical Isotopes, Inc. 70380 Ganaxolone 250mg $650 2021-12-16 Buy
Sigma-Aldrich G7795 Ganaxolone solid 25mg $677 2024-03-01 Buy
Sigma-Aldrich G7795 Ganaxolone solid 5mg $196 2024-03-01 Buy
TRC G235005 Ganaxolone 5mg $80 2021-12-16 Buy

Properties

Melting point :190-192°
alpha :D +103°
Boiling point :434.8±18.0 °C(Predicted)
Density :1.036±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~4.2 mg/mL
form :solid
pka :15.18±0.70(Predicted)
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ganaxolone is a synthetic neurosteroid which functions as a stereoselective modulator of GABAA receptors. Studies indicate that ganaxolone enhances GABA-evoked chloride currents in Xenopus oocytes. It is known that the compound modulates GABAA receptors by inhibiting GABAA receptor-chloride channel ligand binding and enhancing ligand binding at the benzodiazepine site. Alternatively, ganaxolone increases serotonergic neuron firing in rats after 3 to 7 days. Studies conducted on animal seizure models demonstrate that ganaxolone displays anticonvulsant effects. Furthermore, ganaxolone suppresses seizures in mice induced by maximal electroshock (ED50 of 29.7 mg/kg i.p.).

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