GS 143
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- $46 - $2660.9
- Product name: GS 143
- CAS: 916232-21-8
- MF: C28H19FN2O4
- MW: 466.46
- EINECS:
- MDL Number:MFCD30182334
- Synonyms:GS 143;4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid;4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation;Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-;GS143, 10 mM in DMSO;IκB Ubiquitination Inhibitor, GS143
30 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Tocris
- TRC
Package
- 003
- 2mg
- 5mg
- 50
- 10mg
- 25mg
- 50mg
- 10
- 100mg
- 200mg
- 250mg
- 0.5g
- 1G
- 001
- 002
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging2mg
- Price$46
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging5mg
- Price$63
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging10mg
- Price$88
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging25mg
- Price$159
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging50mg
- Price$239
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging100mg
- Price$338
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01BDEV
- Product description4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid
- Packaging200mg
- Price$482
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127625
- Product description(E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98%
- Packaging1G
- Price$2095
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127625
- Product description(E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98%
- Packaging100MG
- Price$355
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127625
- Product description(E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98%
- Packaging25MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerBiosynth
- Product numberRLB23221
- Product description4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic acid
- Packaging50mg
- Price$835.5
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberRLB23221
- Product description4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic acid
- Packaging0.5g
- Price$2660.9
- Updated2026-06-05
- Buy
- ManufacturerCayman Chemical
- Product number26138
- Product descriptionGS-143 ≥98%
- Packaging50mg
- Price$740
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number26138
- Product descriptionGS-143 ≥98%
- Packaging25mg
- Price$427
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number26138
- Product descriptionGS-143 ≥98%
- Packaging10mg
- Price$184
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number26138
- Product descriptionGS-143 ≥98%
- Packaging5mg
- Price$117
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 2mg | $46 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 5mg | $63 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 10mg | $88 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 25mg | $159 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 50mg | $239 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 100mg | $338 | 2026-05-29 | Buy |
| aablocks | AA01BDEV | 4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid | 200mg | $482 | 2026-05-29 | Buy |
| ACHEMBLOCK | U127625 | (E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98% | 1G | $2095 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127625 | (E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98% | 100MG | $355 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127625 | (E)-4-(3-benzyl-4-((5-(2-fluorophenyl)furan-2-yl)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 98% | 25MG | $135 | 2026-05-27 | Buy |
| Biosynth | RLB23221 | 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic acid | 50mg | $835.5 | 2026-06-05 | Buy |
| Biosynth | RLB23221 | 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic acid | 0.5g | $2660.9 | 2026-06-05 | Buy |
| Cayman Chemical | 26138 | GS-143 ≥98% | 50mg | $740 | 2026-04-30 | Buy |
| Cayman Chemical | 26138 | GS-143 ≥98% | 25mg | $427 | 2026-04-30 | Buy |
| Cayman Chemical | 26138 | GS-143 ≥98% | 10mg | $184 | 2026-04-30 | Buy |
| Cayman Chemical | 26138 | GS-143 ≥98% | 5mg | $117 | 2026-04-30 | Buy |
Properties
Boiling point :667.9±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF:25.0(Max Conc. mg/mL);53.59(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.43(Max Conc. mM)
DMSO:31.38(Max Conc. mg/mL);67.28(Max Conc. mM) form :A crystalline solid
pka :4.20±0.10(Predicted)
color :Pink to red
SMILES :C1=CC=C(C=C1)CC2=NN(C(=O)C2=CC3=CC=C(O3)C4=CC=CC=C4F)C5=CC=C(C=C5)C(=O)O
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF:25.0(Max Conc. mg/mL);53.59(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.43(Max Conc. mM)
DMSO:31.38(Max Conc. mg/mL);67.28(Max Conc. mM) form :A crystalline solid
pka :4.20±0.10(Predicted)
color :Pink to red
SMILES :C1=CC=C(C=C1)CC2=NN(C(=O)C2=CC3=CC=C(O3)C4=CC=CC=C4F)C5=CC=C(C=C5)C(=O)O
Safety Information
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Description
4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic Acid blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells.More related product prices
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