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ChemicalBook >> CAS DataBase List >> GSK484

GSK484

GSK484 price.
  • $37 - $3200
  • Product name: GSK484
  • CAS: 1652591-81-5
  • MF: C27H32ClN5O3
  • MW: 510.04
  • EINECS:
  • MDL Number:
  • Synonyms:GSK484;GSK484 (hydrochloride);CS-2265;PAD4 inhibitor GS484;GSK484 HCl;((3S,4R)-3-amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride;AOB6992;GTPL8577
57 prices
Selected condition:
Brand
  • ACHEMBLOCK
  • AK Scientific
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Synthonix
  • TRC
Package
  • 500μg
  • 1mg
  • 1g
  • 50mg
  • 250mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solution)
  • 5mg
  • 10mg
  • 25MG
  • 100MG
  • 10mM(1mLinDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • ManufacturerACHEMBLOCK
  • Product numberS88563
  • Product descriptionGSK484 98%
  • Packaging25MG
  • Price$180
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS88563
  • Product descriptionGSK484 98%
  • Packaging100MG
  • Price$510
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5686
  • Product descriptionGSK484
  • Packaging100mg
  • Price$2663
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging25mg
  • Price$718
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging5mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0052
  • Product descriptionGSK484 98%
  • Packaging10mg
  • Price$370
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging10mM(1mLinDMSO)
  • Price$283
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging10mM(1mLinDMSO)
  • Price$283
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging5mg
  • Price$294
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$329
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$329
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging10mg
  • Price$503
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging5mg
  • Price$216
  • Updated2026-05-25
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging5mg
  • Price$216
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-100514
  • Product descriptionGSK484 hydrochloride 99.48%
  • Packaging25mg
  • Price$855
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S7803
  • Product descriptionGSK484 HCl 99.98%
  • Packaging25mg
  • Price$653
  • Updated2026-05-25
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK S88563 GSK484 98% 25MG $180 2026-05-25 Buy
ACHEMBLOCK S88563 GSK484 98% 100MG $510 2026-05-25 Buy
AK Scientific SYN5686 GSK484 100mg $2663 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 25mg $718 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 5mg $254 2021-12-16 Buy
Apolloscientific BISN0052 GSK484 98% 10mg $370 2021-12-16 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 10mM(1mLinDMSO) $283 2026-05-25 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 10mM(1mLinDMSO) $283 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 5mg $294 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 10mM*1mLinDMSO(Solid+Solvent) $329 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 10mM*1mLinDMSO(Solution) $329 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 10mg $503 2026-05-26 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 5mg $216 2026-05-25 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 5mg $216 2026-05-26 Buy
Arctom HY-100514 GSK484 hydrochloride 99.48% 25mg $855 2026-05-26 Buy
Arctom SLK-S7803 GSK484 HCl 99.98% 25mg $653 2026-05-25 Buy

Properties

storage temp. :2-8°C
solubility :DMSO:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
Ethanol:25.0(Max Conc. mg/mL);49.01(Max Conc. mM)
PBS buffer (pH 7.2):5.0(Max Conc. mg/mL);9.8(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);58.82(Max Conc. mM) form :powder
color :white to beige
Water Solubility :H2O: 2mg/mL, clear (warmed)
InChIKey :MULKOGJHUZTANI-JEGYXLSDNA-N
SMILES :C(C1CC1)N1C2=CC=CC=C2C=C1C1=NC2=CC(C(N3CC[C@@H](O)[C@@H](N)C3)=O)=CC(OC)=C2N1C.Cl |&1:22,24,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GSK484 is a reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils. It exhibits favorable pharmacokinetic profiles in mouse and rat. See the Structural Genomics Consortium (SGC) website for more information.