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ChemicalBook >> CAS DataBase List >> GW441756

GW441756

$12 - $2841
Product name: GW441756
CAS: 504433-23-2
MF: C17H13N3O
MW: 275.31
EINECS:
MDL Number:MFCD08703104
Synonyms:1,3-DIHYDRO-3-[(1-METHYL-1H-INDOL-3-YL)METHYLENE]-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE;GW 441756;2H-Pyrrolo[3,2-b]pyridin-2-one, 1,3-dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-;(Z)-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;-3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3,2-b]pyridin-2(3H)-one;3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one;3-[(1-METHYLINDOL-3-YL)METHYLIDENE]-1H-PYRROLO[3,2-B]PYRIDIN-2-ONE;HYDROCHLORIDE;GW 441756; GW-441756

Price55 Properties Safety Information Description

55 prices

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Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Tocris
TRC

Package

250mg
500mg
1000mg
10mM(1mLinDMSO)
50.00g
50
100.00g
10
250.00g
1mg
10mM(in 1mL DMSO)
5mg
10mg
25MG
50mg
100MG
1G
10mM(in1mLDMSO)

Manufactureraablocks
Product numberAA006Z5M
Product descriptionGW441756 98%
Packaging1mg
Price$12
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA006Z5M
Product descriptionGW441756 98%
Packaging5mg
Price$22
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA006Z5M
Product descriptionGW441756 98%
Packaging10mg
Price$31
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberO33829
Product descriptionGW441756 98%
Packaging5MG
Price$30
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33829
Product descriptionGW441756 98%
Packaging25MG
Price$75
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33829
Product descriptionGW441756 98%
Packaging100MG
Price$235
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberO33829
Product descriptionGW441756 98%
Packaging1G
Price$935
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1044-M050
Product descriptionGW-441756 ≥95%
Packaging50mg
Price$491
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1044-M010
Product descriptionGW-441756 ≥95%
Packaging10mg
Price$124
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1044-M005
Product descriptionGW-441756 ≥95%
Packaging5mg
Price$108
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1044-M001
Product descriptionGW-441756 ≥95%
Packaging1mg
Price$65
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product number2452AH
Product descriptionGW441756
Packaging25mg
Price$184
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberSYN1044
Product descriptionGW441756
Packaging5mg
Price$120
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2452AH
Product descriptionGW441756
Packaging100mg
Price$363
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberSYN1044
Product descriptionGW441756
Packaging50mg
Price$475
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000638
Product descriptionGW-441756 95.00%
Packaging5MG
Price$719.95
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA006Z5M	GW441756 98%	1mg	$12	2026-05-28	Buy
aablocks	AA006Z5M	GW441756 98%	5mg	$22	2026-05-28	Buy
aablocks	AA006Z5M	GW441756 98%	10mg	$31	2026-05-28	Buy
ACHEMBLOCK	O33829	GW441756 98%	5MG	$30	2026-05-27	Buy
ACHEMBLOCK	O33829	GW441756 98%	25MG	$75	2026-05-27	Buy
ACHEMBLOCK	O33829	GW441756 98%	100MG	$235	2026-05-27	Buy
ACHEMBLOCK	O33829	GW441756 98%	1G	$935	2026-05-27	Buy
Adipogen Life Sciences	SYN-1044-M050	GW-441756 ≥95%	50mg	$491	2026-05-06	Buy
Adipogen Life Sciences	SYN-1044-M010	GW-441756 ≥95%	10mg	$124	2026-05-06	Buy
Adipogen Life Sciences	SYN-1044-M005	GW-441756 ≥95%	5mg	$108	2026-05-06	Buy
Adipogen Life Sciences	SYN-1044-M001	GW-441756 ≥95%	1mg	$65	2026-05-06	Buy
AK Scientific	2452AH	GW441756	25mg	$184	2021-12-16	Buy
AK Scientific	SYN1044	GW441756	5mg	$120	2021-12-16	Buy
AK Scientific	2452AH	GW441756	100mg	$363	2021-12-16	Buy
AK Scientific	SYN1044	GW441756	50mg	$475	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000638	GW-441756 95.00%	5MG	$719.95	2021-12-16	Buy

Next Last

Properties

Boiling point :568.0±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 5 mg/ml).
pka :11.04±0.20(Predicted)
form :solid
color :Orange
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The high affinity nerve growth factor (NGF) receptor, also known as NGF tyrosine kinase receptor A (TrkA), is involved in the development and maturation of the nervous system. Aberrant expression is associated with certain forms of cancer and congenital insensitivity to pain with anhidrosis. GW 441756 is a potent inhibitor of TrkA (IC50 = 2 nM). It displays >100-fold selectivity over a panel of related kinases. GW 441756 has been used to clarify the role of TrkA in regulating gene expression in neuroblastoma cells and, more recently, in amyloid-β protein precursor cleavage in neuroglioma cells.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. VDM Biochemicals Jinan Trio PharmaTech Co., Ltd. China Langchem Inc. Dalian Meilun Biotech Co., Ltd. Jinan Bond Chemical Technology Co., Ltd. Haoyuan Chemexpress Co., Ltd. SYN|thesis med chem P/L Shanghai Aladdin Bio-Chem Technology Co.,LTD

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GW441756

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