GW5074
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- $5 - $2040
- Product name: GW5074
- CAS: 220904-83-6
- MF: C15H8Br2INO2
- MW: 520.94
- EINECS:
- MDL Number:MFCD09971042
- Synonyms:RAF1 KINASE INHIBITOR I;(3Z)-3-[(3,5-DIBROMO-4-HYDROXYPHENYL)METHYLIDENE]-5-IODO-1H-INDOL-2-ONE;5-IODO-3-[(3,5-DIBROMO-4-HYDROXYPHENYL)METHYLENE]-2-INDOLINONE;3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE;3-(3,5-DIBROMO-4-HYDROXYBENZYLIDINE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE;GW5074;2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-;3-(3,5-dibromo-4-hydroxybenzyliden)-5-iodo-1,3-dihydroindol-2-one
68 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 5mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 10mg
- 50
- 20mg
- 10mM(in1mLDMSO)
- 25mg
- 50mg
- 100mg
- 250mg
- 0.5g
- 1G
- 5G
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥97%
- Packaging25mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging50mg
- Price$80
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging100mg
- Price$121
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥97%
- Packaging5mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007PK0
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging250mg
- Price$200
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65712
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging250MG
- Price$230
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65712
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging1G
- Price$490
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65712
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98%
- Packaging5G
- Price$2040
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2453AH
- Product descriptionGW5074
- Packaging1g
- Price$537
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2453AH
- Product descriptionGW5074
- Packaging10mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging250mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging100mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging50mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000120
- Product description3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00%
- Packaging10MG
- Price$702.19
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000120
- Product description3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00%
- Packaging50MG
- Price$1199.42
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥97% | 25mg | $48 | 2026-05-28 | Buy |
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 50mg | $80 | 2026-05-28 | Buy |
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 100mg | $121 | 2026-05-28 | Buy |
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥97% | 5mg | $13 | 2026-05-28 | Buy |
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA007PK0 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 250mg | $200 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65712 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 250MG | $230 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65712 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 1G | $490 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65712 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98% | 5G | $2040 | 2026-05-27 | Buy |
| AK Scientific | 2453AH | GW5074 | 1g | $537 | 2021-12-16 | Buy |
| AK Scientific | 2453AH | GW5074 | 10mg | $193 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 250mg | $208 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 100mg | $125 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 50mg | $84 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000120 | 3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00% | 10MG | $702.19 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000120 | 3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00% | 50MG | $1199.42 | 2021-12-16 | Buy |
Properties
Boiling point :561.4±50.0 °C(Predicted)
Density :2.248±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble
form :solid
pka :5.86±0.25(Predicted)
color :yellow to orange-brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)
InChIKey :LMXYVLFTZRPNRV-XCVCLJGOSA-N
SMILES :N1C2=C(C=C(I)C=C2)C(=CC2=CC(Br)=C(O)C(Br)=C2)C1=O
CAS DataBase Reference :220904-83-6
Density :2.248±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble
form :solid
pka :5.86±0.25(Predicted)
color :yellow to orange-brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChI :InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)
InChIKey :LMXYVLFTZRPNRV-XCVCLJGOSA-N
SMILES :N1C2=C(C=C(I)C=C2)C(=CC2=CC(Br)=C(O)C(Br)=C2)C1=O
CAS DataBase Reference :220904-83-6
Safety Information
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Description
GW-5074 (220904-83-6) is a potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. GW-5074 displays neuroprotective effects in vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.More related product prices
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Suppliers and manufacturers
Tianjin Kailiqi Biotechnology Co., Ltd.
Guizhou Yituo Chemical Technology Co., Ltd
Shanghai Boyle Chemical Co., Ltd.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chembest Research Laboratories Limited
VDM Biochemicals
Jinan Trio PharmaTech Co., Ltd.
ChemShuttle, Inc.
BOC Sciences
Dalian Meilun Biotech Co., Ltd.