GW5074
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- $5 - $1300
- Product name: GW5074
- CAS: 220904-83-6
- MF: C15H8Br2INO2
- MW: 520.94
- EINECS:
- MDL Number:MFCD09971042
- Synonyms:RAF1 KINASE INHIBITOR I;(3Z)-3-[(3,5-DIBROMO-4-HYDROXYPHENYL)METHYLIDENE]-5-IODO-1H-INDOL-2-ONE;5-IODO-3-[(3,5-DIBROMO-4-HYDROXYPHENYL)METHYLENE]-2-INDOLINONE;3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE;3-(3,5-DIBROMO-4-HYDROXYBENZYLIDINE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE;GW5074;2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-;3-(3,5-dibromo-4-hydroxybenzyliden)-5-iodo-1,3-dihydroindol-2-one
34 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1mg
- 10mg
- 10
- 5mg
- 50
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2453AH
- Product descriptionGW5074
- Packaging10mg
- Price$193
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2453AH
- Product descriptionGW5074
- Packaging1g
- Price$537
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging50mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging100mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA471753
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+%
- Packaging250mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000120
- Product description3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00%
- Packaging10MG
- Price$702.19
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000120
- Product description3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00%
- Packaging50MG
- Price$1199.42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1405
- Product descriptionGW5074
- Packaging250mg
- Price$314
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569076
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569076
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98%
- Packaging250mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS569076
- Product description3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98%
- Packaging1g
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60312
- Product descriptionGW5074 ≥98%
- Packaging20mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1984
- Product descriptionGW5074 99%
- Packaging5mg
- Price$93.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1984
- Product descriptionGW5074 99%
- Packaging25mg
- Price$313.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010368
- Product descriptionGW 5074 ≥98% (mixture of cis and trans)
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010368
- Product descriptionGW 5074 ≥98% (mixture of cis and trans)
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2453AH | GW5074 | 10mg | $193 | 2021-12-16 | Buy |
| AK Scientific | 2453AH | GW5074 | 1g | $537 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 50mg | $84 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 100mg | $125 | 2021-12-16 | Buy |
| Ambeed | A471753 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one 98+% | 250mg | $208 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000120 | 3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00% | 10MG | $702.19 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000120 | 3-(3,5-DIBROMO-4-HYDROXY-BENZYLIDENE)-5-IODO-1,3-DIHYDRO-INDOL-2-ONE 95.00% | 50MG | $1199.42 | 2021-12-16 | Buy |
| ApexBio Technology | B1405 | GW5074 | 250mg | $314 | 2021-12-16 | Buy |
| Arctom | AS569076 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98% | 100mg | $5 | 2021-12-16 | Buy |
| Arctom | AS569076 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98% | 250mg | $7 | 2021-12-16 | Buy |
| Arctom | AS569076 | 3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one ≥98% | 1g | $15 | 2021-12-16 | Buy |
| Arctom | CFN60312 | GW5074 ≥98% | 20mg | $288 | 2021-12-16 | Buy |
| Axon Medchem | Axon1984 | GW5074 99% | 5mg | $93.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon1984 | GW5074 99% | 25mg | $313.5 | 2021-12-16 | Buy |
| Cayman Chemical | 10010368 | GW 5074 ≥98% (mixture of cis and trans) | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 10010368 | GW 5074 ≥98% (mixture of cis and trans) | 5mg | $116 | 2024-03-01 | Buy |
Properties
Boiling point :561.4±50.0 °C(Predicted)
Density :2.248±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble
form :solid
pka :5.86±0.25(Predicted)
color :yellow to orange-brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :LMXYVLFTZRPNRV-XCVCLJGOSA-N
CAS DataBase Reference :220904-83-6
Density :2.248±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble
form :solid
pka :5.86±0.25(Predicted)
color :yellow to orange-brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :LMXYVLFTZRPNRV-XCVCLJGOSA-N
CAS DataBase Reference :220904-83-6
Safety Information
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Description
GW-5074 (220904-83-6) is a potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. GW-5074 displays neuroprotective effects in vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Dideu Industries Group Limited
Finetech Industry Limited
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
![(3Z)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one](https://img.chemicalbook.com/ProductImageEN/2019-12/small/6fe7ce67-2ff7-463f-8bd4-313145366791.png){kind=small}