Gemfibrozil
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- $5 - $2055.9
- Product name: Gemfibrozil
- CAS: 25812-30-0
- MF: C15H22O3
- MW: 250.33
- EINECS:247-280-2
- MDL Number:MFCD00079335
- Synonyms:PENTANOIC ACID, 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYL-;5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID;5-(2,5-DIMETHYL-PHENOXY)-2,2-DIMETHYL-PENTANOIC ACID;2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID;2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID;GEMFIBROZIL;Gemcitabine intermediates;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
50 prices
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Brand
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Aronis compounds
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 100μg
- 500μg
- 50μg
- 10mM(in 1mL DMSO)
- 50mg
- y0000513
- 1mg
- y0000514
- 100mg
- 200mg
- 250mg
- 500mg
- 1G
- 5g
- 10g
- 25g
- 50g
- 100g
- 250g
- 500g
- 1000g
- ManufacturerAHH
- Product numberAPI-1649
- Product descriptionGemfibrozil 98%
- Packaging1000g
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH900
- Product descriptionGemfibrozil
- Packaging25g
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging5g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging10g
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging25g
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging100g
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA640007
- Product descriptionGemfibrozil 98%
- Packaging500g
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002816
- Product descriptionGemfibrozil 95.00%
- Packaging1G
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002816
- Product descriptionGemfibrozil 95.00%
- Packaging10G
- Price$2055.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1947
- Product descriptionGemfibrozil
- Packaging100mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1947
- Product descriptionGemfibrozil
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1947
- Product descriptionGemfibrozil
- Packaging500mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAronis compounds
- Product numberBBC/228
- Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoicacid
- Packaging1g
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb593446
- Product descriptionGemfibrozil
- Packaging50μg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134440
- Product descriptionGemfibrozil (Lopid) >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1649 | Gemfibrozil 98% | 1000g | $490 | 2021-12-16 | Buy |
| AK Scientific | H900 | Gemfibrozil | 25g | $70 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 100mg | $5 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 5g | $6 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 10g | $11 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 25g | $26 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 100g | $74 | 2021-12-16 | Buy |
| Ambeed | A640007 | Gemfibrozil 98% | 500g | $263 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002816 | Gemfibrozil 95.00% | 1G | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002816 | Gemfibrozil 95.00% | 10G | $2055.9 | 2021-12-16 | Buy |
| ApexBio Technology | B1947 | Gemfibrozil | 100mg | $42 | 2021-12-16 | Buy |
| ApexBio Technology | B1947 | Gemfibrozil | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B1947 | Gemfibrozil | 500mg | $86 | 2021-12-16 | Buy |
| Aronis compounds | BBC/228 | 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoicacid | 1g | $35 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb593446 | Gemfibrozil | 50μg | $425 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb134440 | Gemfibrozil (Lopid) >99% | 100mg | $510 | 2021-12-16 | Buy |
Properties
Melting point :61-63°C
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Gemfibrozil is a fibrate that activates peroxisome proliferator-activator α (PPARα, EC50 = 193 μM) with 100% efficacy. It also activates PPARγ (EC50 = 148 μM), but with only 79% efficacy. Presumably through its effects on PPARα, gemfibrozil lowers triglycerides and increases high density lipoprotein cholesterol levels and is used in the context of atherogenic dyslipidemia. Gemfibrozil strongly binds liver fatty acid-binding protein (Ki = 1.8 μM). Phase II metabolites of gemfibrozil inhibit certain cytochrome P450 isoforms, increasing drug-drug interaction risks.More related product prices
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Suppliers and manufacturers
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