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ChemicalBook >> CAS DataBase List >> Gilteritinib

Gilteritinib

Gilteritinib price.
  • $12 - $1500
  • Product name: Gilteritinib
  • CAS: 1254053-43-4
  • MF: C29H44N8O3
  • MW: 552.71
  • EINECS:
  • MDL Number:MFCD28144685
  • Synonyms:ASP-2215;2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-;6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide;6-ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide;Gilteritinib (ASP2215);6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydr;ASP2215(Gilteritinib);Gilteritinib(free base)
Price57 Properties Safety Information Description
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  • aablocks
  • ACHEMBLOCK
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
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  • Matrix Scientific
  • TRC
  • Usbiological
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  • 10mM*1mLinDMSO
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging1mg
  • Price$12
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging2mg
  • Price$16
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging5mg
  • Price$20
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging10mg
  • Price$25
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging50mg
  • Price$33
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging100mg
  • Price$49
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging250mg
  • Price$87
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging100MG
  • Price$55
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging100MG
  • Price$55
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging25MG
  • Price$25
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging25MG
  • Price$25
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging1G
  • Price$230
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging1G
  • Price$230
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging5G
  • Price$780
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging5G
  • Price$780
  • Updated2026-05-27
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  • ManufacturerApexBio Technology
  • Product numberA4691
  • Product descriptionGilteritinib
  • Packaging10mg
  • Price$171
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 1mg $12 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 2mg $16 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 5mg $20 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 10mg $25 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 50mg $33 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 100mg $49 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 250mg $87 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 100MG $55 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 100MG $55 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 25MG $25 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 25MG $25 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 1G $230 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 1G $230 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 5G $780 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 5G $780 2026-05-27 Buy
ApexBio Technology A4691 Gilteritinib 10mg $171 2026-05-06 Buy
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Properties

Melting point :>157°C (dec.)
Boiling point :696.9±55.0 °C(Predicted)
Density :1.242±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (25 mg/ml)
form :solid
pka :14.39±0.50(Predicted)
color :Off-white to pale pink
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :GYQYAJJFPNQOOW-UHFFFAOYSA-N
SMILES :C1(C(N)=O)=NC(CC)=C(NC2CCOCC2)N=C1NC1=CC=C(N2CCC(N3CCN(C)CC3)CC2)C(OC)=C1

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Gilteritinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3; IC50 = 5 nM for the wild-type enzyme). It inhibits mutant forms of FLT3, including FLT3 with the internal tandem duplication mutation (FLT3-ITD), FLT3-ITD expressing the F691L mutation, and FLT3 with various tyrosine kinase domain mutations (FLT3-TKD; IC50s =1.4-1.8, 12.2, and 0.7-2 nM, respectively). Gilteritinib also inhibits Axl and c-Kit with IC50 values of 41 and 102 nM, respectively. It decreases the viability of blast cells isolated from patients with relapsed acute myeloid leukemia (AML) in a concentration-dependent manner. Formulations containing gilteritinib have been used in the treatment of AML.

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Suppliers and manufacturers

shandong perfect biotechnology co.ltd
Gilteritinib
$0.00 /1g
Gilteritinib CAS:1254053-43-4
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Gilteritinib
$0.00 /1g
Gilteritinib CAS:1254053-43-4
Moxin Chemicals
Gilteritinib
$0.00 /10mg
Gilteritinib CAS:1254053-43-4
career henan chemical co
ASP-2215
$1.00 /100g
ASP-2215 CAS:1254053-43-4
TargetMol Chemicals Inc.
Gilteritinib
$34.00 /1mg
Gilteritinib CAS:1254053-43-4
Suzhou ARTK Medchem Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Suzhou Ryan Pharmachem Technology Co.,Ltd.
Xi'an Yutbon Pharmaceutical Technology Co., Ltd