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ChemicalBook >> CAS DataBase List >> Gilteritinib

Gilteritinib

Gilteritinib price.
  • $12 - $1815
  • Product name: Gilteritinib
  • CAS: 1254053-43-4
  • MF: C29H44N8O3
  • MW: 552.71
  • EINECS:
  • MDL Number:MFCD28144685
  • Synonyms:2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-;6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide;6-ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide;Gilteritinib (ASP2215);6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydr;ASP2215(Gilteritinib);Gilteritinib(free base);CS-2849
Price52 Properties Safety Information Description
52 prices
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  • aablocks
  • ACHEMBLOCK
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
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  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO
  • 1mg
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  • 100.00mg
  • 200mg
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  • 250mg
  • 1.00g
  • 1G
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging1mg
  • Price$12
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging2mg
  • Price$16
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging5mg
  • Price$20
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging10mg
  • Price$25
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging50mg
  • Price$33
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging100mg
  • Price$49
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000NJX
  • Product description6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97%
  • Packaging250mg
  • Price$87
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging100MG
  • Price$55
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging25MG
  • Price$25
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging1G
  • Price$230
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13966
  • Product descriptionGilteritinib 98%
  • Packaging5G
  • Price$780
  • Updated2026-05-27
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  • ManufacturerApexBio Technology
  • Product numberA4691
  • Product descriptionGilteritinib
  • Packaging10mg
  • Price$171
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA4691
  • Product descriptionGilteritinib
  • Packaging5mg
  • Price$107
  • Updated2026-05-06
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  • ManufacturerArctom
  • Product numberHY-12432
  • Product descriptionGilteritinib 99.84%
  • Packaging5mg
  • Price$95
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-12432
  • Product descriptionGilteritinib 99.84%
  • Packaging10mg
  • Price$143
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-12432R
  • Product descriptionGilteritinib (Standard) 99.60%
  • Packaging5mg
  • Price$190
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 1mg $12 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 2mg $16 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 5mg $20 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 10mg $25 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 50mg $33 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 100mg $49 2026-05-25 Buy
aablocks AA000NJX 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide 97% 250mg $87 2026-05-25 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 100MG $55 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 25MG $25 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 1G $230 2026-05-27 Buy
ACHEMBLOCK L13966 Gilteritinib 98% 5G $780 2026-05-27 Buy
ApexBio Technology A4691 Gilteritinib 10mg $171 2026-05-06 Buy
ApexBio Technology A4691 Gilteritinib 5mg $107 2026-05-06 Buy
Arctom HY-12432 Gilteritinib 99.84% 5mg $95 2026-05-26 Buy
Arctom HY-12432 Gilteritinib 99.84% 10mg $143 2026-05-26 Buy
Arctom HY-12432R Gilteritinib (Standard) 99.60% 5mg $190 2026-05-26 Buy
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Properties

Melting point :>157°C (dec.)
Boiling point :696.9±55.0 °C(Predicted)
Density :1.242±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (25 mg/ml)
form :solid
pka :14.39±0.50(Predicted)
color :Off-white to pale pink
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :GYQYAJJFPNQOOW-UHFFFAOYSA-N
SMILES :C1(C(N)=O)=NC(CC)=C(NC2CCOCC2)N=C1NC1=CC=C(N2CCC(N3CCN(C)CC3)CC2)C(OC)=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Gilteritinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3; IC50 = 5 nM for the wild-type enzyme). It inhibits mutant forms of FLT3, including FLT3 with the internal tandem duplication mutation (FLT3-ITD), FLT3-ITD expressing the F691L mutation, and FLT3 with various tyrosine kinase domain mutations (FLT3-TKD; IC50s =1.4-1.8, 12.2, and 0.7-2 nM, respectively). Gilteritinib also inhibits Axl and c-Kit with IC50 values of 41 and 102 nM, respectively. It decreases the viability of blast cells isolated from patients with relapsed acute myeloid leukemia (AML) in a concentration-dependent manner. Formulations containing gilteritinib have been used in the treatment of AML.

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Suppliers and manufacturers

Shanghai Famo Bio-chemical Technology Company Ltd. Anqing Benro pharmachem Technology Co.,Ltd. Adamas Reagent, Ltd. Suzhou Ryan Pharmaceutical Technology Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai Hope Chem Co., Ltd.， Haoyuan Chemexpress Co., Ltd. Guangzhou Isun Pharmaceutical Co., Ltd AdooQ BioScience, LLC TargetMol Chemicals Inc.