HELENALIN
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- $160 - $660
- Product name: HELENALIN
- CAS: 6754-13-8
- MF: C15H18O4
- MW: 262.3
- EINECS:
- MDL Number:MFCD01674580
- Synonyms:(3as-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-ethyl-3-methylene ;HELENALIN(SH);HELENALIN;6alpha,8beta-dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oicacid12,8-lactone ;a-dimethyl-3-methyleneazuleno[6,5-b]-furan-2,5-dione ;ambrosa-2,11(13)-dien-12-oicacid,6-alpha,8-beta-dihydroxy-4-oxo-,12,8-lacton ;ambrosa-2,11(13)-dien-12-oicacid,6alpha,8beta-dihydroxy-4-oxo-,12,8-lactone ;azuleno(6,5-b)furan-2,5-dione,3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dim
7 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 0.25mg
- 500μG
- 500ug
- 1mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0435-M001
- Product descriptionHelenalin ≥96%(HPLC)
- Packaging1mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2004CA
- Product descriptionHelenalin
- Packaging1mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17050
- Product descriptionHelenalin ≥98%
- Packaging1mg
- Price$504
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0078850
- Product descriptionHelenalin 98.29%
- Packaging500ug
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0078850
- Product descriptionHelenalin 98.29%
- Packaging1mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number374000
- Product descriptionHelenalin, A. chamissonis ssp. foliosa
- Packaging500μG
- Price$634
- Updated2025-07-31
- Buy
- ManufacturerTRC
- Product numberH230000
- Product descriptionHelenalin
- Packaging0.25mg
- Price$160
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0435-M001 | Helenalin ≥96%(HPLC) | 1mg | $390 | 2021-12-16 | Buy |
| AK Scientific | 2004CA | Helenalin | 1mg | $660 | 2021-12-16 | Buy |
| Cayman Chemical | 17050 | Helenalin ≥98% | 1mg | $504 | 2024-03-01 | Buy |
| ChemScene | CS-0078850 | Helenalin 98.29% | 500ug | $270 | 2021-12-16 | Buy |
| ChemScene | CS-0078850 | Helenalin 98.29% | 1mg | $410 | 2021-12-16 | Buy |
| Sigma-Aldrich | 374000 | Helenalin, A. chamissonis ssp. foliosa | 500μG | $634 | 2025-07-31 | Buy |
| TRC | H230000 | Helenalin | 0.25mg | $160 | 2021-12-16 | Buy |
Properties
Melting point :167-168°
alpha :D25 -102.8° (c = 3.64 in 95% ethanol)
Boiling point :325.55°C (rough estimate)
Density :1.0772 (rough estimate)
refractive index :1.4300 (estimate)
storage temp. :-20°
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
form :White to off-white solid.
pka :13.29±0.60(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
InChIKey :ZVLOPMNVFLSSAA-XEPQRQSNSA-N
SMILES :O1[C@H]2[C@H]([C@@H]([C@]3([C@H]([C@@H](C2)C)C=CC3=O)C)O)C(=C)C1=O
LogP :0.870
alpha :D25 -102.8° (c = 3.64 in 95% ethanol)
Boiling point :325.55°C (rough estimate)
Density :1.0772 (rough estimate)
refractive index :1.4300 (estimate)
storage temp. :-20°
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
form :White to off-white solid.
pka :13.29±0.60(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
InChIKey :ZVLOPMNVFLSSAA-XEPQRQSNSA-N
SMILES :O1[C@H]2[C@H]([C@@H]([C@]3([C@H]([C@@H](C2)C)C=CC3=O)C)O)C(=C)C1=O
LogP :0.870
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-κB at doses from 1 to 20 μM. Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it alkylates these groups on the p65 subunit of NF-κB. It also suppresses the proliferation of cancer cells through multiple mechanisms, including the prevention of signaling through NF-κB. Helenalin has antibacterial and anti-protozoal activities.Related product price
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Suppliers and manufacturers
Career Henan Chemica Co
ANHUI WITOP BIOTECH CO., LTD
Dideu Industries Group Limited
Shanghai Acmec Biochemical Technology Co., Ltd.
SHANGHAI KEAN TECHNOLOGY CO., LTD.
J & K SCIENTIFIC LTD.
Quality Control Solutions Ltd.
Sichuan Wei Keqi Biological Technology Co., Ltd.
