HELLEBRIN
|
- $50 - $503.35
- Product name: HELLEBRIN
- CAS: 13289-18-4
- MF: C36H52O15
- MW: 724.79
- EINECS:236-303-1
- MDL Number:MFCD03265649
- Synonyms:HELLEBORUS SP;HELLEBRIN;HELLEBRIN, HELLEBORUS SP;14-dihydroxy-19-oxo--mannopyranosyl)oxy)- ;5-beta-bufa-20,22-dienolide,3-beta-((6-deoxy-4-o-beta-d-glucopyranosyl-alpha-l ;hellebrigenin-gluco-rhamnosid ;hellebrigeninglucorhamnoside ;3β-[(4-O-β-D-Glucopyranosyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-bufa-20,22-dienolide
5 prices
Selected condition：
Brand
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 1mg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0475-M001
- Product descriptionHellebrin ≥99%(HPLCandUVAbsorbance)
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0475-M005
- Product descriptionHellebrin ≥99%(HPLCandUVAbsorbance)
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001856
- Product descriptionHELLEBRIN 95.00%
- Packaging5MG
- Price$503.35
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21442
- Product descriptionHellebrin ≥99%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21442
- Product descriptionHellebrin ≥99%
- Packaging5mg
- Price$238
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0475-M001 | Hellebrin ≥99%(HPLCandUVAbsorbance) | 1mg | $50 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0475-M005 | Hellebrin ≥99%(HPLCandUVAbsorbance) | 5mg | $200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001856 | HELLEBRIN 95.00% | 5MG | $503.35 | 2021-12-16 | Buy |
| Cayman Chemical | 21442 | Hellebrin ≥99% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 21442 | Hellebrin ≥99% | 5mg | $238 | 2024-03-01 | Buy |
Properties
Melting point :283-284°
alpha :D20 -23.4° (50% methanol)
Boiling point :635.25°C (rough estimate)
Density :1.1881 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :Store at -20°C, protect from light
solubility :Water:4.0(Max Conc. mg/mL);5.52(Max Conc. mM)
pka :12.89±0.70(Predicted)
form :White to off-white solid.
alpha :D20 -23.4° (50% methanol)
Boiling point :635.25°C (rough estimate)
Density :1.1881 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :Store at -20°C, protect from light
solubility :Water:4.0(Max Conc. mg/mL);5.52(Max Conc. mM)
pka :12.89±0.70(Predicted)
form :White to off-white solid.
Safety Information
| Symbol(GHS): |
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Hellebrin is a cardiotonic glycoside which presents a bufadienolide-steroid structure. Besides ouabain, from the class of cardenolides hellebrin is the second unique water soluble cardiotonic glycoside. Extremely potent inhibitor of Na+/K+-ATPase (sodium pump) blocking the active efflux of Na+ and reuptake of K+ of this membrane enzyme. Shows a positive inotropic effect by increasing the intracellular Ca2+ concentration. Hellebrin is a strong immunosuppressor inhibiting T cell activity with much higher potency than cortisol or cyclosporin A Induces caspase-dependent apoptosis.More related product prices
