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ChemicalBook >> CAS DataBase List >> HJC0197

HJC0197

HJC0197 price.
  • $11 - $2302
  • Product name: HJC0197
  • CAS: 1383539-73-8
  • MF: C19H21N3OS
  • MW: 339.45
  • EINECS:
  • MDL Number:MFCD27966183
  • Synonyms:HJC0197;5-Pyrimidinecarbonitrile, 4-cyclopentyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-;HJC 0197 (HJC0197);HJC0197,cAMP-signaling,activation,GEF,cellular,Ras,inhibit,HJC-0197,HJC 0197,phosphorylation,processes,Inhibitor;6-Cyclopentyl-2-((2,5-dimethylbenzyl)thio)-4-oxo-1,4-dihydropyrimidine-5-carbonitrile;HJC0197, 10 mM in DMSO
Price30 Properties Safety Information Description
30 prices
Selected condition：
Brand
  • aablocks
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50.00mg
  • 50mg
  • 100.00mg
  • 100mg
  • 250.00mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 ≥98%
  • Packaging10mg
  • Price$41
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 ≥98%
  • Packaging25mg
  • Price$88
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 ≥98%
  • Packaging2mg
  • Price$11
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 ≥98%
  • Packaging5mg
  • Price$23
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 99%
  • Packaging50mg
  • Price$125
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EPCG
  • Product descriptionHJC0197 99%
  • Packaging100mg
  • Price$212
  • Updated2026-05-30
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002135
  • Product description4-CYCLOPENTYL-2-(2,5-DIMETHYLBENZYLSULFANYL)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBONITRILE 95.00%
  • Packaging5MG
  • Price$495.22
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3387
  • Product descriptionHJC0197
  • Packaging10mg
  • Price$249
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3387
  • Product descriptionHJC0197
  • Packaging5mg
  • Price$155
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S0837
  • Product descriptionHJC0197 99.98%
  • Packaging5mg
  • Price$378
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S0837
  • Product descriptionHJC0197 99.98%
  • Packaging25mg
  • Price$1140
  • Updated2026-05-26
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3326
  • Product descriptionHJC0197
  • Packaging25mg
  • Price$330
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3326
  • Product descriptionHJC0197
  • Packaging5mg
  • Price$99
  • Updated2026-05-19
  • Buy
  • ManufacturerBiosynth
  • Product numberIFC53973
  • Product descriptionHJC0197
  • Packaging50mg
  • Price$1439.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberIFC53973
  • Product descriptionHJC0197
  • Packaging25mg
  • Price$1034.5
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberIFC53973
  • Product descriptionHJC0197
  • Packaging100mg
  • Price$2302
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EPCG HJC0197 ≥98% 10mg $41 2026-05-30 Buy
aablocks AA01EPCG HJC0197 ≥98% 25mg $88 2026-05-30 Buy
aablocks AA01EPCG HJC0197 ≥98% 2mg $11 2026-05-30 Buy
aablocks AA01EPCG HJC0197 ≥98% 5mg $23 2026-05-30 Buy
aablocks AA01EPCG HJC0197 99% 50mg $125 2026-05-30 Buy
aablocks AA01EPCG HJC0197 99% 100mg $212 2026-05-30 Buy
American Custom Chemicals Corporation INB0002135 4-CYCLOPENTYL-2-(2,5-DIMETHYLBENZYLSULFANYL)-6-OXO-1,6-DIHYDROPYRIMIDINE-5-CARBONITRILE 95.00% 5MG $495.22 2021-12-16 Buy
ApexBio Technology C3387 HJC0197 10mg $249 2026-05-06 Buy
ApexBio Technology C3387 HJC0197 5mg $155 2026-05-06 Buy
Arctom SLK-S0837 HJC0197 99.98% 5mg $378 2026-05-26 Buy
Arctom SLK-S0837 HJC0197 99.98% 25mg $1140 2026-05-26 Buy
Axon Medchem Axon3326 HJC0197 25mg $330 2026-05-19 Buy
Axon Medchem Axon3326 HJC0197 5mg $99 2026-05-19 Buy
Biosynth IFC53973 HJC0197 50mg $1439.5 2026-06-04 Buy
Biosynth IFC53973 HJC0197 25mg $1034.5 2026-06-04 Buy
Biosynth IFC53973 HJC0197 100mg $2302 2026-06-04 Buy
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Properties

solubility :DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.2 mg/ml; DMSO: 5 mg/ml
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). HJC0197 is a cell-permeable inhibitor of Epac1 and Epac2 (IC50 = 5.9 μM for Epac2). It inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM, but has no effect on cAMP-induced type I and II PKA activity at this concentration. Pretreatment of HEK293 cells expressing either Epac1 or Epac2 with 10 μM HJC0197 completely blocks Epac-mediated phosphorylation of Akt. HJC0197 has been used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
HJC0197
$49.00
HJC0197 CAS:1383539-73-8
BOC Sciences Shanghai Lollane Biological Technology Co.,Ltd. Shanghai Beckham Medical Technology Co., Ltd Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai SuperLan Chemcial Technique Centre Henan Alfa Chemical Co., Ltd InvivoChem