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ChemicalBook >> CAS DataBase List >> HO-2 (human recombinant)

HO-2 (human recombinant)

HO-2 (human recombinant) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 50μg
  • ManufacturerCayman Chemical
  • Product number22732
  • Product descriptionHO-2 (human recombinant)
  • Packaging50μg
  • Price$242
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 22732 HO-2 (human recombinant) 50μg $242 2024-03-01 Buy

Properties


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Description

Heme oxygenase-2 (HO-2) is a constitutively active heme oxygenase encoded by the HMOX2 gene. It is a membrane-bound enzyme that catalyzes the cleavage of heme to give carbon monoxide (CO), ferrous ions (Fe2+), and biliverdin, with biliverdin being further processed into bilirubin. HO-2 is found in neurons, testes, and endothelial and smooth muscle cells from cerebral vessels. HO-2 protects against apoptotic neuronal cell death in models of ischemic injury and oxidative stress. It also acts as an oxygen sensor to inhibit systemic vascular reactivity and reduce cell death in response to hypoxia.