Hexamethylphosphoramide

Melting point :7 °C (lit.)
Boiling point :230-232 °C/740 mmHg (lit.)
Density :1.03 g/mL at 25 °C (lit.)
vapor density :6.18 (vs air)
vapor pressure :0.07 mm Hg ( 25 °C)
refractive index :n20/D 1.459(lit.)
Flash point :222 °F
storage temp. :Inert atmosphere,Room Temperature
solubility :Chloroform (Soluble), Methanol (Slightly)
pka :4.69±0.70(Predicted)
form :liquid
color :Colorless to light yellow liquid
Odor :Spicy odor (no threshold data)
Water Solubility :Miscible
FreezingPoint :7℃
Merck :14,4725
BRN :1099903
Henry's Law Constant :4.9×10² mol/(m³Pa) at 25℃, Duchowicz et al. (2020)
Dielectric constant :30.0（20℃）
Stability :Stable. Incompatible with strong acids, strong oxidizing agents.
InChI :1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3
InChIKey :GNOIPBMMFNIUFM-UHFFFAOYSA-N
SMILES :CN(C)P(=O)(N(C)C)N(C)C
CAS DataBase Reference :680-31-9(CAS DataBase Reference)
IARC :2B (Vol. 15, Sup 7, 71) 1999
NIST Chemistry Reference :N,N,N',N',N",N'-Hexamethylphosphorotriamide(680-31-9)
EPA Substance Registry System :Hexamethylphosphoramide (680-31-9)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger H350 May cause cancer Carcinogenicity Category 1A, 1B Danger
Precautionary statements:	P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P363 Wash contaminated clothing before reuse.