Isradipine
|
- $35 - $1732.5
- Product name: Isradipine
- CAS: 75695-93-1
- MF: C19H21N3O5
- MW: 371.39
- EINECS:630-420-5
- MDL Number:MFCD00153820
- Synonyms:PN-200-110;Presca;Prescal;4-(4-Benzofurazanyl)-2，6-dimethyl-1，4-dihydro-3，5-pyridinedicarboxylic acid methyl 1-methylethyl ester;4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic [chemical name] acid methyl 1-methylethyl ester;Dynacrine;Iomir;Rebfiden
57 prices
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Brand
- AccelPharmtech
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 5mg
- y0000366
- 2mg
- 25mg
- 50mg
- 10
- 50
- 10MG
- 100MG
- 0.1g
- 250MG
- 10mM(in1mLDMSO)
- 200mg
- 1G
- 5G
- 10G
- 125 mg
- ManufacturerAccelPharmtech
- Product numberAT4812
- Product descriptionIsradipine 98%
- Packaging5G
- Price$270
- Updated2026-05-21
- Buy
- ManufacturerAccelPharmtech
- Product numberAT4812
- Product descriptionIsradipine 98%
- Packaging10G
- Price$420
- Updated2026-05-21
- Buy
- ManufacturerAHH
- Product numberAPI-1593
- Product descriptionIsradipine 98%
- Packaging0.1g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1593
- Product descriptionIsradipine 97%
- Packaging0.1g
- Price$300
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberK297
- Product descriptionIsradipine
- Packaging5mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003052
- Product descriptionISRADIPINE 95.00%
- Packaging5MG
- Price$445
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003052
- Product descriptionISRADIPINE 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003052
- Product descriptionISRADIPINE 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8453
- Product descriptionIsradipine(Dynacirc)
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8453
- Product descriptionIsradipine (Dynacirc)
- Packaging10mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8453
- Product descriptionIsradipine (Dynacirc)
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8453
- Product descriptionIsradipine (Dynacirc)
- Packaging25mg
- Price$121
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8453
- Product descriptionIsradipine (Dynacirc)
- Packaging50mg
- Price$209
- Updated2026-05-06
- Buy
- ManufacturerAvaChem
- Product number6444
- Product descriptionIsradipine 98%
- Packaging50mg
- Price$256
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6444
- Product descriptionIsradipine 98%
- Packaging10mg
- Price$64
- Updated2026-05-22
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3501
- Product descriptionIsradipine
- Packaging10mg
- Price$66
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | AT4812 | Isradipine 98% | 5G | $270 | 2026-05-21 | Buy |
| AccelPharmtech | AT4812 | Isradipine 98% | 10G | $420 | 2026-05-21 | Buy |
| AHH | API-1593 | Isradipine 98% | 0.1g | $300 | 2021-12-16 | Buy |
| AHH | API-1593 | Isradipine 97% | 0.1g | $300 | 2026-05-26 | Buy |
| AK Scientific | K297 | Isradipine | 5mg | $35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003052 | ISRADIPINE 95.00% | 5MG | $445 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003052 | ISRADIPINE 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003052 | ISRADIPINE 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
| ApexBio Technology | A8453 | Isradipine(Dynacirc) | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A8453 | Isradipine (Dynacirc) | 10mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A8453 | Isradipine (Dynacirc) | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | A8453 | Isradipine (Dynacirc) | 25mg | $121 | 2026-05-06 | Buy |
| ApexBio Technology | A8453 | Isradipine (Dynacirc) | 50mg | $209 | 2026-05-06 | Buy |
| AvaChem | 6444 | Isradipine 98% | 50mg | $256 | 2026-05-22 | Buy |
| AvaChem | 6444 | Isradipine 98% | 10mg | $64 | 2026-05-22 | Buy |
| Axon Medchem | Axon3501 | Isradipine | 10mg | $66 | 2026-05-19 | Buy |
Properties
Melting point :166-1680C
Boiling point :501.9±60.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~26 mg/mL
form :solid
pka :2.56±0.70(Predicted)
color :yellow
Merck :14,5240
BCS Class :2/4
Stability :Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
InChIKey :HMJIYCCIJYRONP-UHFFFAOYSA-N
SMILES :C1(C)NC(C)=C(C(OC(C)C)=O)C(C2C3C(C=CC=2)=NON=3)C=1C(OC)=O
CAS DataBase Reference :75695-93-1(CAS DataBase Reference)
NIST Chemistry Reference :Isradipine(75695-93-1)
Boiling point :501.9±60.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~26 mg/mL
form :solid
pka :2.56±0.70(Predicted)
color :yellow
Merck :14,5240
BCS Class :2/4
Stability :Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
InChIKey :HMJIYCCIJYRONP-UHFFFAOYSA-N
SMILES :C1(C)NC(C)=C(C(OC(C)C)=O)C(C2C3C(C=CC=2)=NON=3)C=1C(OC)=O
CAS DataBase Reference :75695-93-1(CAS DataBase Reference)
NIST Chemistry Reference :Isradipine(75695-93-1)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Isradipine is a selective L-type calcium channel blocker with long-acting antihypertensive activity. It demonstrates an EC50 value of 1.4 nM for relaxation of depolarization-induced contractions of rabbit aorta and an EC25 value of 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria. By suppressing calcium influx into the cytoplasm and Cav1.2 expression, isradipine has been shown to attenuate β-amyloid oligomer toxicity in an in vitro model of Alzheimer’s disease.Related product price
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