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ChemicalBook >> CAS DataBase List >> JW 642

JW 642

JW 642 price.
  • $42 - $1363
  • Product name: JW 642
  • CAS: 1416133-89-5
  • MF: C21H20F6N2O3
  • MW: 462.39
  • EINECS:
  • MDL Number:MFCD22987956
  • Synonyms:JW 642;1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(3-phenoxybenzyl)piperazine-1-carboxylate;4-[(3-Phenoxyphenyl)methyl]-1-piperazinecarboxylic acid 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester;JW 642; JW642;1-Piperazinecarboxylic acid, 4-[(3-phenoxyphenyl)methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester;MAGL,inhibit,JW-642,Inhibitor,JW 642,Monoacylglycerol lipase,JW642;JW 642, 10 mM in DMSO
Price53 Properties Safety Information Description
53 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 1mg
  • 50
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95
  • Packaging10mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95
  • Packaging25mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95
  • Packaging50mg
  • Price$115
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95
  • Packaging100mg
  • Price$197
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95%
  • Packaging250mg
  • Price$397
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009C9P
  • Product descriptionJW 642 95%
  • Packaging1g
  • Price$952
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226704
  • Product descriptionJW 642 97.00%
  • Packaging1G
  • Price$1155
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226704
  • Product descriptionJW 642 97.00%
  • Packaging250MG
  • Price$550
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226704
  • Product descriptionJW 642 97.00%
  • Packaging100MG
  • Price$405
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3755AH
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate
  • Packaging5mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3755AH
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate
  • Packaging50mg
  • Price$596
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3755AH
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate
  • Packaging100mg
  • Price$969
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5759
  • Product descriptionJW 642
  • Packaging50mg
  • Price$950
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5759
  • Product descriptionJW642
  • Packaging50mg
  • Price$961
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5759
  • Product descriptionJW 642
  • Packaging5mg
  • Price$154
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5759
  • Product descriptionJW642
  • Packaging5mg
  • Price$156
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009C9P JW 642 95 10mg $47 2026-05-28 Buy
aablocks AA009C9P JW 642 95 25mg $72 2026-05-28 Buy
aablocks AA009C9P JW 642 95 50mg $115 2026-05-28 Buy
aablocks AA009C9P JW 642 95 100mg $197 2026-05-28 Buy
aablocks AA009C9P JW 642 95% 250mg $397 2026-05-28 Buy
aablocks AA009C9P JW 642 95% 1g $952 2026-05-28 Buy
ACHEMBLOCK Y226704 JW 642 97.00% 1G $1155 2026-05-27 Buy
ACHEMBLOCK Y226704 JW 642 97.00% 250MG $550 2026-05-27 Buy
ACHEMBLOCK Y226704 JW 642 97.00% 100MG $405 2026-05-27 Buy
AK Scientific 3755AH 1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate 5mg $162 2021-12-16 Buy
AK Scientific 3755AH 1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate 50mg $596 2021-12-16 Buy
AK Scientific 3755AH 1,1,1,3,3,3-Hexafluoropropan-2-yl4-(3-phenoxybenzyl)piperazine-1-carboxylate 100mg $969 2021-12-16 Buy
ApexBio Technology B5759 JW 642 50mg $950 2026-05-06 Buy
ApexBio Technology B5759 JW642 50mg $961 2021-12-16 Buy
ApexBio Technology B5759 JW 642 5mg $154 2026-05-06 Buy
ApexBio Technology B5759 JW642 5mg $156 2021-12-16 Buy
Next Last

Properties

Melting point :68-70°C
Boiling point :432.9±45.0 °C(Predicted)
Density :1.354±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :6.13±0.10(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to arachidonic acid and glycerol, thus terminating its biological function. JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
JW 642
$33.00
JW 642 CAS:1416133-89-5
ATK CHEMICAL COMPANY LIMITED
Aladdin Scientific BOC Sciences AdooQ BioScience, LLC Cochemical Ltd. LETOPHARM LIMITED SPIRO PHARMA Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.