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ChemicalBook >> CAS DataBase List >> JW 618

JW 618

JW 618 price.
  • $53 - $596
  • Product name: JW 618
  • CAS: 1416133-88-4
  • MF: C17H14F6N2O2
  • MW: 392.3
  • EINECS:
  • MDL Number:
  • Synonyms:JW 618;RBZKWMMBPOHSDF-UHFFFAOYSA-N;Carbamic acid, N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester;N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-,2,2,2-trifluoro-1-(trifluoromethyl)ethylester-carbamicacid
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Arctom
  • Cayman Chemical
Package
  • 10mg(127.45mM*200μLinMethylacetate)(Solvent)
  • 10mg
  • 5mg
  • 5mg(127.45mM*100μLinMethylacetate)(Solvent)
  • 25mg
  • 50mg
  • Manufactureraablocks
  • Product numberAA01EOXD
  • Product descriptionJW 618 98%
  • Packaging5mg
  • Price$53
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EOXD
  • Product descriptionJW 618 ≥98%
  • Packaging50mg
  • Price$493
  • Updated2026-05-30
  • Buy
  • ManufacturerAK Scientific
  • Product number0861DV
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate
  • Packaging50mg
  • Price$596
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0861DV
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate
  • Packaging25mg
  • Price$379
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0861DV
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate
  • Packaging5mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0861DV
  • Product description1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate
  • Packaging10mg
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-117722
  • Product descriptionJW 618
  • Packaging10mg(127.45mM*200μLinMethylacetate)(Solvent)
  • Price$227
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-117722
  • Product descriptionJW 618
  • Packaging5mg(127.45mM*100μLinMethylacetate)(Solvent)
  • Price$124
  • Updated2026-05-26
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging50mg
  • Price$448
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging50mg
  • Price$493
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging25mg
  • Price$253
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging25mg
  • Price$279
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging5mg
  • Price$59
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging5mg
  • Price$65
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging10mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11790
  • Product descriptionJW 618 ≥98%
  • Packaging10mg
  • Price$119
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EOXD JW 618 98% 5mg $53 2026-05-30 Buy
aablocks AA01EOXD JW 618 ≥98% 50mg $493 2026-05-30 Buy
AK Scientific 0861DV 1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate 50mg $596 2021-12-16 Buy
AK Scientific 0861DV 1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate 25mg $379 2021-12-16 Buy
AK Scientific 0861DV 1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate 5mg $162 2021-12-16 Buy
AK Scientific 0861DV 1,1,1,3,3,3-Hexafluoropropan-2-ylN-methyl-N-[(3-pyridin-4-ylphenyl)methyl]carbamate 10mg $217 2021-12-16 Buy
Arctom HY-117722 JW 618 10mg(127.45mM*200μLinMethylacetate)(Solvent) $227 2026-05-26 Buy
Arctom HY-117722 JW 618 5mg(127.45mM*100μLinMethylacetate)(Solvent) $124 2026-05-26 Buy
Cayman Chemical 11790 JW 618 ≥98% 50mg $448 2024-03-01 Buy
Cayman Chemical 11790 JW 618 ≥98% 50mg $493 2026-04-30 Buy
Cayman Chemical 11790 JW 618 ≥98% 25mg $253 2024-03-01 Buy
Cayman Chemical 11790 JW 618 ≥98% 25mg $279 2026-04-30 Buy
Cayman Chemical 11790 JW 618 ≥98% 5mg $59 2024-03-01 Buy
Cayman Chemical 11790 JW 618 ≥98% 5mg $65 2026-04-30 Buy
Cayman Chemical 11790 JW 618 ≥98% 10mg $108 2024-03-01 Buy
Cayman Chemical 11790 JW 618 ≥98% 10mg $119 2026-04-30 Buy

Properties

Boiling point :380.0±42.0 °C(Predicted)
Density :1.349±0.06 g/cm3(Predicted)
solubility :DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 16 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
pka :5.17±0.26(Predicted)

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to arachidonic acid and glycerol, thus terminating its biological function. JW 618 is an inhibitor of MAGL that displays IC50 values of 123, 385, and 6.9 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. JW 618 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s all > 50 μM for mouse, rat, and human brain membranes).

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Suppliers and manufacturers

BOC Sciences Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. TargetMol Chemicals Inc. Cayman Chemical Company