JW55
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- $14 - $7030
- Product name: JW55
- CAS: 664993-53-7
- MF: C25H26N2O5
- MW: 434.49
- EINECS:-0
- MDL Number:MFCD03863265
- Synonyms:JW55;N-(4-((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)MethylcarbaMoyl)phenyl)furan-2-carboxaMide;N-[4-[[4-(4-METHOXYPHENYL)OXAN-4-YL]METHYLCARBAMOYL]PHENYL]FURAN-2-CARBOXAMIDE;N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW55 N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW 55, >=98%;N-(4-(((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)carbamoyl)phenyl)furan-2-carboxamid;Tankyrase1/2 Inhibitor IV, JW55
56 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 2x10mg
- 10mM*1mLinDMSO
- 5mg
- 25mg
- 1mg
- 10mg
- 10
- 50
- 10mM(in1mLDMSO)
- 50mg
- 100mg
- 250MG
- 1G
- 1000mg
- 5g
- 5.00g
- EvaluationSample
- 10g
- 10.00g
- Manufactureraablocks
- Product numberAA00FBXB
- Product descriptionJW 55 98%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBXB
- Product descriptionJW 55 ≥98%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBXB
- Product descriptionJW 55 ≥98%
- Packaging50mg
- Price$114
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBXB
- Product descriptionJW 55
- Packaging100mg
- Price$178
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33830
- Product descriptionJW55 98%
- Packaging100MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33830
- Product descriptionJW55 98%
- Packaging250MG
- Price$490
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33830
- Product descriptionJW55 98%
- Packaging1G
- Price$1220
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3754AH
- Product descriptionN-[4-[([[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl]amino)carbonyl]phenyl]-2-furamide
- Packaging5mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3754AH
- Product descriptionN-[4-[([[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl]amino)carbonyl]phenyl]-2-furamide
- Packaging10mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA533890
- Product descriptionJW55 98+%
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA533890
- Product descriptionJW55 98+%
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002076
- Product descriptionJW-55 95.00%
- Packaging10MG
- Price$240.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4529
- Product descriptionJW 55
- Packaging50mg
- Price$250
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4529
- Product descriptionJW 55
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4529
- Product descriptionJW 55
- Packaging10mg
- Price$83
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4529
- Product descriptionJW 55
- Packaging10mM(in1mLDMSO)
- Price$90
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00FBXB | JW 55 98% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00FBXB | JW 55 ≥98% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA00FBXB | JW 55 ≥98% | 50mg | $114 | 2026-05-28 | Buy |
| aablocks | AA00FBXB | JW 55 | 100mg | $178 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33830 | JW55 98% | 100MG | $205 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33830 | JW55 98% | 250MG | $490 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33830 | JW55 98% | 1G | $1220 | 2026-05-27 | Buy |
| AK Scientific | 3754AH | N-[4-[([[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl]amino)carbonyl]phenyl]-2-furamide | 5mg | $115 | 2021-12-16 | Buy |
| AK Scientific | 3754AH | N-[4-[([[4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl]amino)carbonyl]phenyl]-2-furamide | 10mg | $158 | 2021-12-16 | Buy |
| Ambeed | A533890 | JW55 98+% | 10mg | $75 | 2021-12-16 | Buy |
| Ambeed | A533890 | JW55 98+% | 50mg | $190 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002076 | JW-55 95.00% | 10MG | $240.45 | 2021-12-16 | Buy |
| ApexBio Technology | A4529 | JW 55 | 50mg | $250 | 2026-05-06 | Buy |
| ApexBio Technology | A4529 | JW 55 | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | A4529 | JW 55 | 10mg | $83 | 2026-05-06 | Buy |
| ApexBio Technology | A4529 | JW 55 | 10mM(in1mLDMSO) | $90 | 2026-05-06 | Buy |
Properties
Melting point :153-155 °C
Boiling point :572.6±50.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.41±0.70(Predicted)
form :powder
color :white to beige
InChI :1S/C25H26N2O5/c1-30-21-10-6-19(7-11-21)25(12-15-31-16-13-25)17-26-23(28)18-4-8-20(9-5-18)27-24(29)22-3-2-14-32-22/h2-11,14H,12-13,15-17H2,1H3,(H,26,28)(H,27,29)
InChIKey :ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
SMILES :O1C=CC=C1C(NC1=CC=C(C(NCC2(C3=CC=C(OC)C=C3)CCOCC2)=O)C=C1)=O
Boiling point :572.6±50.0 °C(Predicted)
Density :1.235±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.41±0.70(Predicted)
form :powder
color :white to beige
InChI :1S/C25H26N2O5/c1-30-21-10-6-19(7-11-21)25(12-15-31-16-13-25)17-26-23(28)18-4-8-20(9-5-18)27-24(29)22-3-2-14-32-22/h2-11,14H,12-13,15-17H2,1H3,(H,26,28)(H,27,29)
InChIKey :ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
SMILES :O1C=CC=C1C(NC1=CC=C(C(NCC2(C3=CC=C(OC)C=C3)CCOCC2)=O)C=C1)=O
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
JW 55 is an inhibitor of the PARP domain of tankyrases (TNKS) 1 and 2 (IC50s = 1.9 and 0.83 μM, respectively). By inhibiting TNKS1/2, JW 55 stabilizes Axin2 and increases degradation of β-catenin, inhibiting the β-catenin signaling pathway (IC50 = 470 nM). It has been shown to decrease canonical Wnt signaling in SW480 and HCT15 colon carcinoma cell lines and to reduce proliferation of SW480 cells in vitro.Suppliers and manufacturers
Jingmo (Xiamen) Biotechnology Co., Ltd
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
BOC Sciences
Shanghai Topbiochem Technology Co., Ltd
Haoyuan Chemexpress Co., Ltd.
Nanjing Dulai Biotechnology Co., Ltd.
AdooQ BioScience, LLC
CEG Chemical Science&Technology Co., Ltd.
AdooQ Bioscience CHINA