KIGAMICIN C
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- $255 - $1133
- Product name: KIGAMICIN C
- CAS: 680571-51-1
- MF: C41H47NO16
- MW: 809.81
- EINECS:
- MDL Number:MFCD09954098
- Synonyms:KIGAMICIN C;Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
6 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
- Usbiological
Package
- 500ug
- 500μg
- 0.5MG
- 2.5mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0003487
- Product descriptionKIGAMICIN C 95.00%
- Packaging0.5MG
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19445
- Product descriptionKigamicin C ≥98%
- Packaging500μg
- Price$303
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19445
- Product descriptionKigamicin C ≥98%
- Packaging2.5mg
- Price$1133
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberK570508
- Product descriptionKigamicinC
- Packaging500μg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberK1765-25
- Product descriptionKigamicin C
- Packaging500ug
- Price$523
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number453048
- Product descriptionKigamicin C
- Packaging500μg
- Price$573
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | PXT0003487 | KIGAMICIN C 95.00% | 0.5MG | $425 | 2021-12-16 | Buy |
| Cayman Chemical | 19445 | Kigamicin C ≥98% | 500μg | $303 | 2024-03-01 | Buy |
| Cayman Chemical | 19445 | Kigamicin C ≥98% | 2.5mg | $1133 | 2024-03-01 | Buy |
| TRC | K570508 | KigamicinC | 500μg | $255 | 2021-12-16 | Buy |
| Usbiological | K1765-25 | Kigamicin C | 500ug | $523 | 2021-12-16 | Buy |
| Usbiological | 453048 | Kigamicin C | 500μg | $573 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :Yellow powder.
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :Yellow powder.
Safety Information
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Description
Kigamicins are natural antitumor antibiotics that selectively kill pancreatic cancer PANC-1 cells only under nutrient-starved conditions. They also show antimicrobial activity against Gram-positive bacteria, including methicillin-resistant S. aureus. Kigamicin C inhibits PANC-1 cell survival in nutrient-deprived media at a 100-fold lower concentration than that required for cells maintained in nutrient-rich media. A related compound, kigamicin D, is active in vivo, suppressing the tumor growth of several pancreatic cancer cell lines in nude mice. It blocks the activation of Akt induced in PANC-1 cells placed in nutrient-deprived media. Kigamicin can also induce necrosis in human myeloma cells, but not normal lymphocytes, maintained in nutrient-rich media (CC50 = 100 nM).Related product price
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