KN-62
|
- $28 - $2245.7
- Product name: KN-62
- CAS: 127191-97-3
- MF: C38H35N5O6S2
- MW: 721.84
- EINECS:
- MDL Number:MFCD00083180
- Synonyms:1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-*N-M ETHYL-L-TYR;KN-62 97%;KN-62, 99+%;4-((2S)-2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenylisoquinolinesulfonicacid;1-(N,O-Bis-[5-isoquinolinesulfonyl]-N-methyl-L-tyrosyl)-4-phenylpiperazine, (S)-5-Isoquinolinesulfonic Acid 4-(2-[(5-Isoquinolinylsulfonyl)methylamino]- 3-oxo-3-[4-phenyl-1-piperazinyl]propyl)phenyl Ester,;5-Isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester;(s)-5-isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester;(1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-N-METHYL-L-TYROSYL)4-PHENYLPIPERAZINE) KN 62
42 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Synthonix
- Thermo Scientific Chemicals
- Tocris
- Usbiological
Package
- .5mg
- 10mg
- 100mg
- 250mg
- 1g
- 0.5 mg
- 1
- 10mM(in 1mL DMSO)
- 1unit
- 25mg
- 50mg
- EvaluationSample
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- ManufacturerAK Scientific
- Product numberY0221
- Product descriptionKN-62
- Packaging50mg
- Price$1097
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging25mg
- Price$236
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging1mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging10mM(in1mLDMSO)
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8180
- Product descriptionKN-62
- Packaging10mM(in 1mL DMSO)
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146104
- Product descriptionKN-62 >98%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146104
- Product descriptionKN-62 >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146104
- Product descriptionKN-62 >98%
- Packaging1g
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13318
- Product descriptionKN-62 ≥98%
- Packaging25mg
- Price$403
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13318
- Product descriptionKN-62 ≥98%
- Packaging25mg
- Price$444
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0221 | KN-62 | 50mg | $1097 | 2021-12-16 | Buy |
| ApexBio Technology | A8180 | KN-62 | 25mg | $236 | 2026-05-06 | Buy |
| ApexBio Technology | A8180 | KN-62 | 25mg | $240 | 2021-12-16 | Buy |
| ApexBio Technology | A8180 | KN-62 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8180 | KN-62 | EvaluationSample | $30 | 2026-05-06 | Buy |
| ApexBio Technology | A8180 | KN-62 | 1mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A8180 | KN-62 | 1mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | A8180 | KN-62 | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A8180 | KN-62 | 5mg | $70 | 2026-05-06 | Buy |
| ApexBio Technology | A8180 | KN-62 | 10mM(in1mLDMSO) | $110 | 2026-05-06 | Buy |
| ApexBio Technology | A8180 | KN-62 | 10mM(in 1mL DMSO) | $125 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146104 | KN-62 >98% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146104 | KN-62 >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146104 | KN-62 >98% | 1g | $2245.7 | 2021-12-16 | Buy |
| Cayman Chemical | 13318 | KN-62 ≥98% | 25mg | $403 | 2024-03-01 | Buy |
| Cayman Chemical | 13318 | KN-62 ≥98% | 25mg | $444 | 2026-04-30 | Buy |
Properties
Melting point :92-94°C
Boiling point :964.7±75.0 °C(Predicted)
Density :1.388
storage temp. :-20°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
pka :4.07±0.13(Predicted)
form :solid
color :white
biological source :synthetic (organic)
InChIKey :RJVLFQBBRSMWHX-DHUJRADRSA-N
SMILES :O=S(OC1=CC=C(C[C@@H](C(N2CCN(C3=CC=CC=C3)CC2)=O)N(C)S(C4=CC=CC5=C4C=CN=C5)(=O)=O)C=C1)(C6=CC=CC7=C6C=CN=C7)=O
CAS DataBase Reference :127191-97-3(CAS DataBase Reference)
Boiling point :964.7±75.0 °C(Predicted)
Density :1.388
storage temp. :-20°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
pka :4.07±0.13(Predicted)
form :solid
color :white
biological source :synthetic (organic)
InChIKey :RJVLFQBBRSMWHX-DHUJRADRSA-N
SMILES :O=S(OC1=CC=C(C[C@@H](C(N2CCN(C3=CC=CC=C3)CC2)=O)N(C)S(C4=CC=CC5=C4C=CN=C5)(=O)=O)C=C1)(C6=CC=CC7=C6C=CN=C7)=O
CAS DataBase Reference :127191-97-3(CAS DataBase Reference)
Safety Information
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Description
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII; IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 μM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).More related product prices
27655-40-9 4-Methyl-1-piperazineethanamine N-Aminoethylpiperazine 1-Acetylpiperazine KN-62Related product price
- 27655-40-9
$13.43-1617 - 1-(3-PHENYLPROPYL)PIPERAZINE
$168 - 1-ACETYL-4-METHYLPIPERAZINE HYDROCHLORIDE
$53-672
