KU-0063794
|
- $23 - $2839
- Product name: KU-0063794
- CAS: 938440-64-3
- MF: C25H31N5O4
- MW: 465.55
- EINECS:
- MDL Number:MFCD11977741
- Synonyms:BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol KU-0063794
65 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 2mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 10
- 10.00mg
- 20mg
- 25mg
- 10mM(in 1mL DMSO)
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250mg
- 1g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00GRS1
- Product descriptionrel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98%
- Packaging1mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRS1
- Product descriptionrel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98%
- Packaging5mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRS1
- Product descriptionrel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98
- Packaging25mg
- Price$126
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRS1
- Product descriptionrel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98
- Packaging50mg
- Price$207
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRS1
- Product descriptionrel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98
- Packaging100mg
- Price$366
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212313
- Product descriptionKU-0063794 97%
- Packaging100MG
- Price$515
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212313
- Product descriptionKU-0063794 97%
- Packaging50MG
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M005
- Product descriptionKU-0063794 ≥95%
- Packaging5mg
- Price$97
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M010
- Product descriptionKU-0063794 ≥95%
- Packaging10mg
- Price$162
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M001
- Product descriptionKU-0063794 ≥95%
- Packaging1mg
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M050
- Product descriptionKU-0063794 ≥95%
- Packaging50mg
- Price$486
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M100
- Product descriptionKU-0063794 ≥95%
- Packaging100mg
- Price$702
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1050
- Product descriptionKU 0063794
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1050
- Product descriptionKU 0063794
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000836
- Product descriptionKU 0063794 95.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000836
- Product descriptionKU 0063794 95.00%
- Packaging50MG
- Price$1155
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GRS1 | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98% | 1mg | $23 | 2026-05-28 | Buy |
| aablocks | AA00GRS1 | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98% | 5mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00GRS1 | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98 | 25mg | $126 | 2026-05-28 | Buy |
| aablocks | AA00GRS1 | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98 | 50mg | $207 | 2026-05-28 | Buy |
| aablocks | AA00GRS1 | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol 98 | 100mg | $366 | 2026-05-28 | Buy |
| ACHEMBLOCK | X212313 | KU-0063794 97% | 100MG | $515 | 2026-05-27 | Buy |
| ACHEMBLOCK | X212313 | KU-0063794 97% | 50MG | $280 | 2026-05-27 | Buy |
| Adipogen Life Sciences | SYN-1050-M005 | KU-0063794 ≥95% | 5mg | $97 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M010 | KU-0063794 ≥95% | 10mg | $162 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M001 | KU-0063794 ≥95% | 1mg | $76 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M050 | KU-0063794 ≥95% | 50mg | $486 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M100 | KU-0063794 ≥95% | 100mg | $702 | 2026-05-06 | Buy |
| AK Scientific | SYN1050 | KU 0063794 | 50mg | $470 | 2021-12-16 | Buy |
| AK Scientific | SYN1050 | KU 0063794 | 5mg | $110 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000836 | KU 0063794 95.00% | 10MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000836 | KU 0063794 95.00% | 50MG | $1155 | 2021-12-16 | Buy |
Properties
Boiling point :694.3±65.0 °C(Predicted)
Density :1.248
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
form :powder
pka :14.20±0.10(Predicted)
color :white to beige
InChIKey :RFSMUFRPPYDYRD-CALCHBBNSA-N
SMILES :COc1ccc(cc1CO)-c2ccc3c(nc(nc3n2)N4C[C@H](C)O[C@H](C)C4)N5CCOCC5
Density :1.248
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
form :powder
pka :14.20±0.10(Predicted)
color :white to beige
InChIKey :RFSMUFRPPYDYRD-CALCHBBNSA-N
SMILES :COc1ccc(cc1CO)-c2ccc3c(nc(nc3n2)N4C[C@H](C)O[C@H](C)C4)N5CCOCC5
Safety Information
| Symbol(GHS): |
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||||
| Hazard statements: |
|
||||||||||||||||
| Precautionary statements: |
|
Description
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-0063794 is a cell-permeable, selective dual inhibitor of mTORC1 and mTORC2 (IC50 = 10 nM). It does not affect the activity of 76 other protein kinases or seven lipid kinases, including PI3Ks. Ku-0063794 inhibits cell growth by inducing G1-cell cycle arrest and autophagy, but not apoptosis, and inhibits tumor growth in a xenograft model of renal cell carcinoma (8 mg/kg for 46 days).More related product prices
Rapamycin Erlotinib hydrochloride 1222998-36-8 MK-2206 2HCl AZD-8055 EverolimusRelated product price
-
Rapamycin
$9-6160 -
Erlotinib hydrochloride
$5-3498.6 -
1222998-36-8
$28-4500
Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chembest Research Laboratories Limited
Shangchem Co., Ltd.
VDM Biochemicals
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Shanghai civi chemical technology co.,Ltd
Beijing HuaMeiHuLiBiological Chemical
NCE Biomedical Co.,Ltd.